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11.
Dohnal Vlastislav Gennaro Claudio Savino Pasquale Zezula Pavel 《Multimedia Tools and Applications》2003,21(1):9-33
In order to speedup retrieval in large collections of data, index structures partition the data into subsets so that query requests can be evaluated without examining the entire collection. As the complexity of modern data types grows, metric spaces have become a popular paradigm for similarity retrieval. We propose a new index structure, called D-Index, that combines a novel clustering technique and the pivot-based distance searching strategy to speed up execution of similarity range and nearest neighbor queries for large files with objects stored in disk memories. We have qualitatively analyzed D-Index and verified its properties on actual implementation. We have also compared D-Index with other index structures and demonstrated its superiority on several real-life data sets. Contrary to tree organizations, the D-Index structure is suitable for dynamic environments with a high rate of delete/insert operations. 相似文献
12.
The multimedia multicasting problem 总被引:4,自引:0,他引:4
This paper explores the problems associated with the multicasting of continuous media to support multimedia group applications.
The interaction between multicasting and the delivery of multiple time-correlated continuous-media streams with real-time
delay requirements poses various new and interesting problems in research on communication protocols and architectures. We
describe these problems, and identify where the opportunities are for effective solutions, all in the context of providing
an overview of the current state of research in multimedia multicasting. The issues we discuss include quality of service,
resource reservations, routing, error and traffic control, heterogeneity, and the use of hierarchical coding and open-loop
control techniques. 相似文献
13.
Approximate similarity retrieval with M-trees 总被引:4,自引:0,他引:4
Pavel Zezula Pasquale Savino Giuseppe Amato Fausto Rabitti 《The VLDB Journal The International Journal on Very Large Data Bases》1998,7(4):275-293
Motivated by the urgent need to improve the efficiency of similarity queries, approximate similarity retrieval is investigated
in the environment of a metric tree index called the M-tree. Three different approximation techniques are proposed, which
show how to forsake query precision for improved performance. Measures are defined that can quantify the improvements in performance
efficiency and the quality of approximations. The proposed approximation techniques are then tested on various synthetic and
real-life files. The evidence obtained from the experiments confirms our hypothesis that a high-quality approximated similarity
search can be performed at a much lower cost than that needed to obtain the exact results. The proposed approximation techniques
are scalable and appear to be independent of the metric used. Extensions of these techniques to the environments of other
similarity search indexes are also discussed.
Received July 7, 1998 / Accepted October 13, 1998 相似文献
14.
This paper presents a novel approach for the integration of a set of eXtensible Markup Language (XML) Schemas. The proposed approach is specialized for XML, almost automatic, semantic and “light”. Further, an original peculiarity is that it is parametric w.r.t. a “severity” level against which the integration task is performed. The paper describes the approach in all details, illustrates various theoretical results, presents the experiments we have performed for testing it and, finally, compares it with various related approaches already proposed in the literature. 相似文献
15.
16.
Chiara Trincianti Vincenzo Meleca Edoardo La Porta Maurizio Bruschi Giovanni Candiano Andrea Garbarino Xhuliana Kajana Alberto Preda Francesca Lugani Gian Marco Ghiggeri Andrea Angeletti Pasquale Esposito Enrico Verrina 《International journal of molecular sciences》2022,23(10)
Peritoneal dialysis (PD) represents the dialysis modality of choice for pediatric patients with end-stage kidney disease. Indeed, compared with hemodialysis (HD), it offers many advantages, including more flexibility, reduction of the risk of hospital-acquired infections, preservation of residual kidney function, and a better quality of life. However, despite these positive aspects, PD may be associated with several long-term complications that may impair both patient’s general health and PD adequacy. In this view, chronic inflammation, caused by different factors, has a detrimental impact on the structure and function of the peritoneal membrane, leading to sclerosis and consequent PD failure both in adults and children. Although several studies investigated the complex pathogenic pathways underlying peritoneal membrane alterations, these processes remain still to explore. Understanding these mechanisms may provide novel approaches to improve the clinical outcome of pediatric PD patients through the identification of subjects at high risk of complications and the implementation of personalized interventions. In this review, we discuss the main experimental and clinical experiences exploring the potentiality of the proteomic analysis of peritoneal fluids and extracellular vesicles as a source of novel biomarkers in pediatric peritoneal dialysis. 相似文献
17.
Pasquale Avella 《Computers & Operations Research》2012,39(7):1625-1632
The p-median problem (PMP) consists of locating p facilities (medians) in order to minimize the sum of distances from each client to the nearest facility. The interest in the large-scale PMP arises from applications in cluster analysis, where a set of patterns has to be partitioned into subsets (clusters) on the base of similarity.In this paper we introduce a new heuristic for large-scale PMP instances, based on Lagrangean relaxation. It consists of three main components: subgradient column generation, combining subgradient optimization with column generation; a “core” heuristic, which computes an upper bound by solving a reduced problem defined by a subset of the original variables chosen on a base of Lagrangean reduced costs; and an aggregation procedure that defines reduced size instances by aggregating together clients with the facilities. Computational results show that the proposed heuristic is able to compute good quality lower and upper bounds for instances up to 90,000 clients and potential facilities. 相似文献
18.
19.
Andrea Cerciello Pasquale Del Gaudio Marco Cantarini Rita P. Aquino 《Drug development and industrial pharmacy》2016,42(12):2063-2069
Context: Ketoprofen lysinate (KL) is one of the most widely used non-steroidal anti-inflammatory drugs in the symptomatic treatment of some chronic inflammatory diseases. Compared to ketoprofen, KL shows better pharmacokinetics and tolerability. However, due to its short half-life of 1–2?h, a multiple dose regimen is required for oral administration. Thus, the present work deals with its encapsulation in a hydrogel-based system by prilling in order to prolong its activity.Objective: In this paper, we propose alginate and pectin as carriers and release tailoring agent for the development of hydrogel-based beads for KL retarded and sustained release.Materials and methods: Beads were produced by a Nisco Encapsulator® using alginate or pectin. Operative variables were optimized to produce beads with desired morphology and size. Solid state properties were analyzed by SEM and DSC. Drug release performance was studied by Pharmacopeia pH-change assay to simulate gastrointestinal environment.Results and discussion: Prilling technique was successfully used to encapsulate high soluble drugs as KL in polysaccharides-based hydrogels. Pectin proved to be a proper polymer able to encapsulate ketoprofen lysine salt. Formulation (F8) showed good morphological properties and size, high drug content (15.6%) and encapsulation efficiency (93.5%) and promising drug release profiles. Hosting F8 in an acid-resistant capsule (DR®caps) a delivery platform has been developed to control KL release in a delayed (90?min lag time) and prolonged way (270?min complete release).Conclusion: The platform may be proposed as potentially useful in the oral administration of NSAIDs in chronic inflammatory diseases affected by circadian rhythm. 相似文献
20.
Francesco Merola Simonetta Grilli Sara Coppola Veronica Vespini Sergio De Nicola Pasquale Maddalena Cosimo Carfagna Pietro Ferraro 《Advanced functional materials》2012,22(15):3267-3272
Investigation on the behavior of nematic liquid crystals on functionalized polar dielectric crystal substrates is accomplished. Very interesting effects can be observed in maneuvering liquid crystal droplets on the substrate surface, driven by electric fields generated by pyroelectric effect. Reversible drops fragmentation and self‐assembling in different configurations can be achieved. The dynamics of the observed phenomena is studied and the repeatability of the process is full assessed. 相似文献