全文获取类型
收费全文 | 1664篇 |
免费 | 12篇 |
专业分类
电工技术 | 12篇 |
化学工业 | 53篇 |
机械仪表 | 15篇 |
建筑科学 | 15篇 |
能源动力 | 3篇 |
轻工业 | 45篇 |
石油天然气 | 2篇 |
无线电 | 24篇 |
一般工业技术 | 24篇 |
冶金工业 | 1429篇 |
原子能技术 | 2篇 |
自动化技术 | 52篇 |
出版年
2019年 | 3篇 |
2017年 | 11篇 |
2016年 | 5篇 |
2013年 | 10篇 |
2012年 | 7篇 |
2011年 | 6篇 |
2010年 | 7篇 |
2009年 | 7篇 |
2008年 | 18篇 |
2007年 | 13篇 |
2006年 | 9篇 |
2005年 | 6篇 |
2004年 | 12篇 |
2003年 | 6篇 |
2002年 | 6篇 |
2001年 | 9篇 |
2000年 | 7篇 |
1999年 | 43篇 |
1998年 | 436篇 |
1997年 | 256篇 |
1996年 | 146篇 |
1995年 | 96篇 |
1994年 | 70篇 |
1993年 | 103篇 |
1992年 | 10篇 |
1991年 | 30篇 |
1990年 | 29篇 |
1989年 | 19篇 |
1988年 | 21篇 |
1987年 | 24篇 |
1986年 | 13篇 |
1985年 | 13篇 |
1984年 | 4篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 10篇 |
1980年 | 12篇 |
1979年 | 4篇 |
1978年 | 5篇 |
1977年 | 35篇 |
1976年 | 89篇 |
1975年 | 5篇 |
1973年 | 4篇 |
1971年 | 3篇 |
1970年 | 6篇 |
1963年 | 3篇 |
1962年 | 2篇 |
1961年 | 2篇 |
1959年 | 3篇 |
1955年 | 3篇 |
排序方式: 共有1676条查询结果,搜索用时 15 毫秒
131.
This case describes ventricular proarrhythmia as a result of a synchronized internal atrial defibrillation shock in a 29-year-old man with Ebstein's anomaly referred for radiofrequency ablation of a right posterior accessory pathway. During the electrophysiologic study, atrial fibrillation was induced and 3/3 msec shocks of various strengths were delivered between two decapolar defibrillation catheters in the coronary sinus and right atrial appendage. A 2.0-J biphasic shock synchronized to an R wave after a short-long-short ventricular cycle length pattern with a preshock coupling interval of 245 msec induced ventricular fibrillation, which was externally defibrillated with 200 J. This observation has implications for the development of implantable atrial defibrillators. 相似文献
132.
J Moawad JF McKinsey CW Wyble HS Bassiouny LB Schwartz BL Gewertz 《Canadian Metallurgical Quarterly》1997,132(6):613-8; discussion 618-9
133.
Previously, we demonstrated elevated cortisol production/release in response to the administration of the serotonin precursor, L-5-hydroxytryptophan (L-5-HTP) in untreated patients with obstructive sleep apnea (OSA). We hypothesized that if this elevated cortisol response to L-5-HTP was related to OSA, this finding would not be present in OSA patients treated with nasal continuous positive airway pressure (nCPAP). Eleven OSA patients treated for at least 1 month with nCPAP were studied. On two different days, we measured blood cortisol level every 15 min for 4 h following the ingestion of L-5-HTP, 0.4 mg/kg, or placebo, both given with carbidopa, a peripheral tryptophan decarboxylase inhibitor, used to prevent peripheral L-5-HTP metabolism before brain absorption. For a given subject, the cortisol response was calculated as the difference between the area under the curve of the L-5-HTP and placebo responses. In the nCPAP-treated OSA patients, this net cortisol response, 577 +/- 240 min.micrograms/dL, was less than the value found in the previously studied untreated OSA group, 1,198 +/- 227 min.micrograms/dL (p < 0.05) and not different from the previously studied nonapneic control group, 469 +/- 154 min.micrograms/dL. From these results, we speculate that nCPAP treatment reverses the elevated cortisol response to serotonergic stimulation seen in untreated OSA patients. 相似文献
134.
We investigated the extent of induction in sublingual salivary gland cells apoptosis and tumor necrosis factor-alpha (TNF-alpha) expression with chronic ethanol ingestion. The experiments were conducted on rats pair-fed for 8 weeks with alcohol-containing and control liquid diet. The animals were killed, their sublingual glands dissected, and the glandular tissue used for quantization of TNF-alpha expression and the assays of acinar cells apoptosis employing sandwich enzyme immunoassay for histone-associated DNA fragments. The mean value for TNF-alpha in sublingual gland of the control group was 22.3 pg/mg of protein and showed a 1.6-fold increase in the chronic ethanol diet group to 36.5 pg/mg of protein. In comparison with the controls, the sublingual gland of the chronic ethanol diet group also exhibited a 3.4-fold enhancement in acinar cell apoptosis. These findings suggest that chronic ethanol ingestion causes the enhancement in TNF-alpha expression and leads to the induction in salivary gland acinar cells apoptosis. Thus, the diminished secretion of saliva in alcoholics may be a direct result of increased salivary gland apoptosis. 相似文献
135.
136.
BL Johnson 《Canadian Metallurgical Quarterly》1995,31(1):2415-2428
Uncontrolled hazardous waste sites are major environmental and public health concerns in the United States and elsewhere. The identification and remediation of and public health responses to these sites are mandated by the U.S. federal Superfund statute. Since its enactment into law in 1980, approximately 40,000 uncontrolled waste sites have been identified in the United States. Approximately 1,300 of these sites constitute the current national Superfund priority list of sites for remediation. Results from analyses are described that characterize the priority hazardous substances released from Superfund sites and the extent of hazard posed to residential communities. Findings from the United States' experience in responding to uncontrolled waste sites are relevant to other countries as they address similar environmental and public health concerns. 相似文献
137.
138.
139.
Breast conservation and prolonged chemotherapy for locally advanced breast cancer: the University of Michigan experience 总被引:1,自引:0,他引:1
SD Merajver BL Weber R Cody D Zhang M Strawderman KA Calzone V LeClaire A Levin J Irani M Halvie D August M Wicha A Lichter LJ Pierce 《Canadian Metallurgical Quarterly》1997,15(8):2873-2881
PURPOSE: To determine whether breast conservation and prolonged neoadjuvant chemotherapy have efficacy in locally advanced breast cancer (LABC), as measured by survival and rate of breast conservation. MATERIALS AND METHODS: Eighty-nine patients with stage III disease were enrolled at the University of Michigan (UM) onto a prospective nonrandomized trial. Patients received nine 21-day cycles of neoadjuvant chemohormonal therapy that consisted of doxorubicin 30 mg/m2 and cyclophosphamide 750 mg/m2 intravenously on day 1, conjugated estrogens 0.625 mg orally twice daily on days 6 to 8, methotrexate 40 mg/m2 and fluorouracil 500 mg/m2 intravenously on day 8, and tamoxifen 10 mg orally twice daily on days 9 to 14. Patients with a negative biopsy received radiation only, while those with residual disease underwent mastectomy and postoperative radiotherapy. Eight more cycles of chemohormonal therapy were administered after local-regional therapy. RESULTS: The clinical response rate to neoadjuvant therapy was 97%, 28% of patients had a complete pathologic response evaluated at biopsy. Five-year overall and disease-free survival probabilities were 54% and 44%, respectively. The median disease-free survival time was 2.4 years. The 5-year actuarial rates of local-regional control with local failure as only first failure were 82% and 78% following radiotherapy, and mastectomy and radiotherapy, respectively (P = .99). CONCLUSION: Prolonged neoadjuvant chemohormonal therapy and biopsy-driven local therapy have efficacy in LABC, with 28% of patients being candidates for breast conservation and a 5-year overall survival rate of 54%. 相似文献
140.