Maryam Khalid Rizvi;Roshina Rabail;Seemal Munir;Muhammad Waleed Rizvi;Gholamreza Abdi;Rana Muhammad Aadil; 《Food Science & Nutrition》2024,12(9):6226-6241

Delayed conceiving is a failure of a female to attain clinical pregnancy within a year without the use of contraception or any precautionary measure. The females of reproductive age (20–49 years) are the sufferers, that is, about 1.5 million or 10% of couples globally are facing this issue. Delayed conception can be caused by several reasons including diet, lifestyle, and genetic and clinical problems. Deficiencies or overconsumption of any nutrient may also cause delayed conception in females. Dietary deficits such as iron, iodine, zinc, folate, and vitamin D reduce the ovarian reserve. Heavy metals such as copper, manganese, lead, and cadmium also have an impact on fertility. Overconsumption of fast foods and nonhome-made foods increases the likelihood of infertility by 2–3. Smoking, physical activity, age, polycystic ovary syndrome (PCOS), obesity, and depression have all been considered lifestyle and clinical factors. If women have a sedentary lifestyle, too much exercise or obesity both contribute to infertility. In clinical factors, type 1 diabetes, insulin resistance, and hypertension mainly cause infertility. Our focus in this review is on the studies probe that how these variables contributed to delayed conception and how it can be controlled to help combat infertility. Prevention from delayed conception involves consuming a healthy and balanced diet that contains essential nutrients engaging in physical activity and abstaining from smoking, PCOS, and medical issues.  相似文献   

    

Mahabub Alam;Animesh Sarkar;A. S. M. Sayem;Rahul Biswas;M. M. Mahdi Hasan; 《Food Science & Nutrition》2024,12(11):9371-9378

Heat-resistant molds (HRM) pose a significant threat to food industries due to their ability to survive in high temperatures (pasteurization range) and grow in a variety of environments. To understand how inhibiting variables affect HRM growth, this study evaluated the impact of high sugar concentration (50–60°Brix), low pH (3.5–4.5), and temperature (5–15) on the time (tv) to develop detectable colonies (colony diameter = 2 mm) of three HRM strains (Byssochlamys nivea, Byssochlamys fulva, Neosartorya fischeri) isolated from mixed fruit products. The study found that all HRM strains had relatively short periods of time to develop detectable colonies at 50°Brix, while no visible growth was observed at 60°Brix. Byssochlamys nivea was found to be the most susceptible to low temperatures, requiring up to 43 days to develop detectable colonies at 10°C and unable to grow at colder temperatures. The tv varied from 6 to 27 days based on pH and isolates. HRM's resistance to high sugar concentrations and ability to grow in cold environments pose a threat to the microbiological safety of fruit products. The evaluated data were fitted to several statistical distribution models to support further research on the quantitative microbiological risk in processed fruit products. This study provides valuable insights into how inhibiting variables affect HRM growth and can inform efforts to minimize their impact on fruit-based product quality and safety.  相似文献   

    

Kübra Demir;Rana Turgut;Selcen Şentürk;Handan Işıklar;Elif Günalan; 《Food Science & Nutrition》2024,12(12):9951-9973

Understanding the molecular signaling pathways of colorectal cancer (CRC) can be accepted as the first step in treatment strategy. Permanent mTOR signaling activation stimulates the CRC process via various biological processes. It supplies the survival of CRC stem cells, tumorigenesis, morbidity, and decreased response to drugs in CRC pathogenesis. Therefore, inhibition of the mTOR signaling by numerous bioactive components may be effective against CRC. The study aims to discuss the therapeutic capacity of various polyphenols, terpenoids, and alkaloids on CRC via the PI3K/Akt/mTOR pathway. The potential molecular effects of bioactive compounds on the mTOR pathway's upstream and downstream targets are examined. Each bioactive component causes various physiological processes, such as triggering free radical production, disruption of mitochondrial membrane potential, cell cycle arrest, inhibition of CRC stem cell migration, and suppression of glycolysis through mTOR signaling inhibition. As a result, carcinogenesis is inhibited by inducing apoptosis and autophagy. However, it should be noted that studies are primarily in vitro dose-dependent treatment researchers. This study raises awareness about the role of phenolic compounds in treating CRC, contributing to their future use as anticancer agents. These bioactive compounds have the potential to be developed into food supplementation to prevent and treat various cancer types including CRC. This review has the potential to lead to further development of clinical studies. In the future, mTOR inhibition by applying several bioactive agents using advanced drug delivery systems may contribute to CRC treatment with 3D cell culture and in vivo clinical studies.  相似文献   

    

Won-Chun Oh  Yin Liu  Kwang Youn Cho  Md Rokon Ud Dowla Biswas 《Fullerenes, Nanotubes and Carbon Nanostructures》2020,28(11):945-958

Abstract

Polyaniline/Bismuth Vanadate/Graphene Oxide (PANI-BiVO₄-GO) or BGPA composite was prepared by sonochemical deposition of bismuth vanadate-graphene oxide (BiVO₄) nanoparticles on the surface of polyaniline (PANI). The best photocatalytic degradation performance was obtained by 5wt% BGPA composites for MB, RhB, and SO dyes, which is approximately 4 times higher than that of 1% BGPA. Meanwhile, the photocatalytic stability of BiVO₄ was significantly improved by introducing PANI into the PANI-BiVO₄-GO composite. The dramatic promotion of the photocatalytic degradation performance and the photocatalytic stability can be attributed to the formation of a heterojunction free electron between PANI and BiVO₄-GO. The existence of those extra free electrons can dramatically enhance the efficiency of the photogenerated electrons, which accelerate the transfer of photogenerated holes from BiVO₄-GO to PANI, and therefore inhibit the self-oxidation of BiVO₄.  相似文献   

    

Xu Liu  Philip Zimny  Yuning Zhang  Ankit Rana  Roland Nagel  Walter Reisner  William B. Dunbar 《Small (Weinheim an der Bergstrasse, Germany)》2020,16(3)

Solid‐state nanopores are a single‐molecule technique that can provide access to biomolecular information that is otherwise masked by ensemble averaging. A promising application uses pores and barcoding chemistries to map molecular motifs along single DNA molecules. Despite recent research breakthroughs, however, it remains challenging to overcome molecular noise to fully exploit single‐molecule data. Here, an active control technique termed “flossing” that uses a dual nanopore device is presented to trap a proteintagged DNA molecule and up to 100's of back‐and‐forth electrical scans of the molecule are performed in a few seconds. The protein motifs bound to 48.5 kb λ‐DNA are used as detectable features for active triggering of the bidirectional control. Molecular noise is suppressed by averaging the multiscan data to produce averaged intertag distance estimates that are comparable to their known values. Since nanopore feature‐mapping applications require DNA linearization when passing through the pore, a key advantage of flossing is that trans‐pore linearization is increased to >98% by the second scan, compared to 35% for single nanopore passage of the same set of molecules. In concert with barcoding methods, the dual‐pore flossing technique could enable genome mapping and structural variation applications, or mapping loci of epigenetic relevance.  相似文献   

    

Fionn Davitt  Hugh G. Manning  Fred Robinson  Samantha L. Hawken  Subhajit Biswas  Nikolay Petkov  Maart van Druenen  John J. Boland  Gillian Reid  Justin D. Holmes 《Advanced Materials Interfaces》2020,7(16)

Here the controlled growth of SnSe nanowires by a liquid injection chemical vapor deposition (CVD) method employing a distorted octahedral [SnCl₄{ⁿBuSe(CH₂)₃SeⁿBu}] single‐source diselenoether precursor is reported. CVD with this single‐source precursor allows morphological and compositional control of the SnSe_x nanostructures formed, including the transformation of SnSe₂ nanoflakes into SnSe nanowires and again to SnSe nanoflakes with increasing growth temperature. Significantly, highly crystalline SnSe nanowires with an orthorhombic Pnma 62 crystal structure can be controllably synthesized in two growth directions, either <011> or <100>. The ability to tune the growth direction of SnSe will have important implications for devices constructed using these nanocrystals. The SnSe nanowires with a <011> growth direction display a reversible polarity‐dependent memory switching ability, not previously reported for nanoscale SnSe. A resistive switching on/off ratio of 10³ without the use of a current compliance limit is seen, illustrating the potential use of SnSe nanowires for low‐power nonvolatile memory applications.  相似文献   

    

Nilesh K. Tiwari  Abhishek Sharma  Surya P. Singh  M. Jaleel Akhtar  Animesh Biswas 《国际射频与微波计算机辅助工程杂志》2020,30(2)

The purpose of this article is to provide a comprehensive investigation on the resonance phenomenon of microstrip line coupled complementary split‐ring resonator (CSRR) with different orientation and relative size. It is shown that when the relative size of the CSRR is smaller than the host line, the CSRR with its slit oriented orthogonal to the line axis will not excite effectively and show weak resonance behavior. However, when the slit is positioned along the line axis, the cross‐polarization effect comes into play, which excites the CSRR through the mixed coupling. To ensure the correctness, several numerical simulations are carried out for different substrate height and relative permittivity. Finally, a prototype is fabricated and measured for the experimental validation.  相似文献   

    

Huansheng Ning  Jun Wang  Lingfeng Mao  Qingjuan Li  Rana Sadaf Anwar 《Digital Communications & Networks》2020,6(3):377-388

Over the past few years, Radio Frequency IDentification (RFID) has stridden significantly due to its adoption in many business and daily life activities. RFID empowers end-to-end and item-by-item visibility, letting the customers or decision-makers effectively trail the personnel and resources for improved management. Significant research and development in this area have transformed the inexpensive, miniaturized technology of RFIDs without chip inside. Chipless Radio Frequency IDentification (CRFID) is a unique wireless technology based on radar principle to sense, identify, and track the objects. CRFIDs are simplified and miniaturized tags of traditional RFID, which can widely be used in small and cheap objects/applications in our daily life. This paper reviews the definition, principle, and most recent development in CRFIDs. Based on the reported researches, the ElectroMagnetic Spectrum (EMS) method is typical, which has been concerned by many RFID researchers. Therefore, this paper reviews different types of EMS CRFID tag and classifies these tags based on structure design emphasizing their significant geometries in comparison with performance parameters. Antenna and coding methods of the EMS CRFID are also elaborated, contrasting the tag capacity and coding performance. Finally, we briefly summarize the challenges and limitations in this emerging field and look forward to the prospects of future CRFID.  相似文献   

    

Aditi Chatterjee  Jayabrata Biswas  Kiranmoy Das 《International Journal of Communication Systems》2020,33(9)

In recent years, Internet of Things (IoT) devices are used for remote health monitoring. For remotely monitoring a patient, only the health information at different time points are not sufficient; predicted values of biomarkers (for some future time points) are also important. In this article, we propose a powerful statistical model for an efficient dynamic patient monitoring using wireless sensor nodes through Bayesian Learning (BL). We consider the setting where a set of correlated biomarkers are measured from a patient through wireless sensors, but the sensors only report the ordinal outcomes (say, good, fair, high, or very high) to the sink based on some prefixed thresholds. The challenge is to use the ordinal outcomes for monitoring and predicting the health status of the patient under consideration. We propose a linear mixed model where interbiomarker correlations and intrabiomarker dependence are modeled simultaneously. The estimated and the predicted values of the biomarkers are transferred over the internet so that health care providers and the family members of the patient can remotely monitor the patient. Extensive simulation studies are performed to assess practical usefulness of our proposed joint model, and the performance of the proposed joint model is compared to that of some other traditional models used in the literature.  相似文献   

    

E.M.Awad  M.A.Rana  Mushtaq Abed Al-Jubbori 《核技术(英文版)》2020,(12):41-49

Systematic CR-39 bulk etching experiments were conducted over a wide range of concentrations (2-30 N) of NaOH-based etchant. Critical analysis and a deep discus...  相似文献