全文获取类型
收费全文 | 564篇 |
免费 | 15篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 18篇 |
化学工业 | 93篇 |
金属工艺 | 17篇 |
机械仪表 | 18篇 |
建筑科学 | 9篇 |
能源动力 | 26篇 |
轻工业 | 44篇 |
水利工程 | 2篇 |
石油天然气 | 2篇 |
无线电 | 50篇 |
一般工业技术 | 109篇 |
冶金工业 | 145篇 |
原子能技术 | 9篇 |
自动化技术 | 38篇 |
出版年
2023年 | 3篇 |
2022年 | 6篇 |
2021年 | 8篇 |
2020年 | 5篇 |
2019年 | 3篇 |
2018年 | 13篇 |
2017年 | 13篇 |
2016年 | 14篇 |
2015年 | 7篇 |
2014年 | 3篇 |
2013年 | 29篇 |
2012年 | 12篇 |
2011年 | 24篇 |
2010年 | 17篇 |
2009年 | 22篇 |
2008年 | 23篇 |
2007年 | 18篇 |
2006年 | 14篇 |
2005年 | 20篇 |
2004年 | 17篇 |
2003年 | 12篇 |
2002年 | 8篇 |
2001年 | 6篇 |
2000年 | 14篇 |
1999年 | 12篇 |
1998年 | 60篇 |
1997年 | 32篇 |
1996年 | 19篇 |
1995年 | 10篇 |
1994年 | 10篇 |
1993年 | 11篇 |
1992年 | 4篇 |
1991年 | 4篇 |
1990年 | 11篇 |
1989年 | 7篇 |
1988年 | 12篇 |
1987年 | 10篇 |
1985年 | 7篇 |
1984年 | 7篇 |
1983年 | 2篇 |
1981年 | 2篇 |
1980年 | 7篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1977年 | 7篇 |
1976年 | 8篇 |
1975年 | 5篇 |
1974年 | 2篇 |
1973年 | 5篇 |
1967年 | 2篇 |
排序方式: 共有580条查询结果,搜索用时 31 毫秒
31.
Tomokazu Saiki Nobuhisa Nakamura Megumi Miyabe Mizuho Ito Tomomi Minato Kazunori Sango Tatsuaki Matsubara Keiko Naruse 《International journal of molecular sciences》2021,22(11)
Schwann cells play an important role in peripheral nerve function, and their dysfunction has been implicated in the pathogenesis of diabetic neuropathy and other demyelinating diseases. The physiological functions of insulin in Schwann cells remain unclear and therefore define the aim of this study. By using immortalized adult Fischer rat Schwann cells (IFRS1), we investigated the mechanism of the stimulating effects of insulin on the cell proliferation and expression of myelin proteins (myelin protein zero (MPZ) and myelin basic protein (MBP). The application of insulin to IFRS1 cells increased the proliferative activity and induced phosphorylation of Akt and ERK, but not P38-MAPK. The proliferative potential of insulin-stimulated IFRS1 was significantly suppressed by the addition of LY294002, a PI3 kinase inhibitor. The insulin-stimulated increase in MPZ expression was significantly suppressed by the addition of PD98059, a MEK inhibitor. Furthermore, insulin-increased MBP expression was significantly suppressed by the addition of LY294002. These findings suggest that both PI3-K/Akt and ERK/MEK pathways are involved in insulin-induced cell growth and upregulation of MPZ and MBP in IFRS1 Schwann cells. 相似文献
32.
Noriya Izu Toshio Uchida Ichiro Matsubara Toshio Itoh Woosuck Shin Maiko Nishibori 《Materials Research Bulletin》2011,46(8):1168-1176
Very unique core-shell ceria (cerium oxide)/polymer hybrid nanoparticles that have monodispersed spherical structures and are easily dispersed in water or alcohol without the need for a dispersant were reported recently. The formation mechanism of the unique nanoparticles, however, was not clear. In order to clarify the formation mechanism, these nanoparticles were prepared using a polyol method (reflux heating) under varied conditions of temperature, time, and concentration and molecular weight of added polymer (poly(vinylpyrrolidone)). The size of the resultant nanoparticles was strongly and complicatedly dependent on the set temperature used during reflux heating and the poly(vinylpyrrolidone) molecular weight. Furthermore, the size of the nanoparticles increased by a 2-step process as the reflux heating time increased. The IR spectral changes with increasing reflux time indicated the increase in the number of cross-linked polymers in the shell. From these results, the formation mechanism was discussed and proposed. 相似文献
33.
Crystallization behaviours around the glass transition temperature in an amorphous Fe70Nb10B20 alloy were investigated by means of transmission electron microscopy. Dense bcc-Fe nanocrystals initially appeared as the primary phase, followed by the dense formation of the (Fe,Nb)23B6 nanocrystalline phase. The bcc-Fe nanocrystals were formed even by annealing at a temperature that is 38 K lower than the glass transition temperature. A difference of the low temperature behaviours between the present conventional amorphous alloy and a bulk metallic glass was discussed. 相似文献
34.
T Funabiki T Matsubara M Ochiai Y Marugami Y Sakurai S Hasegawa H Imazu 《Canadian Metallurgical Quarterly》1997,46(4):169-172
Theory-driven investigations are necessary for generalization of findings and development of health care policy. Within the environments where nurses practice, however, there often is insufficient time to develop a theory base that supports practice changes or the investigation of their effects. Theories that support such investigations need to incorporate elements associated with both the structure and the process of care delivered as well as the outcomes expected. These same theories also need to specify the focal level of interest for research questions. Incorporating a research template to guide practice investigations facilitates decision making and collection of data. 相似文献
35.
Takeshi Takahashi Kyosuke Kojima Wei Zhang Kanae Sasaki Masaru Ito Hironori Suzuki Masato Kawasaki Soichi Wakatsuki Terunao Takahara Hideki Shibata Masatoshi Maki 《International journal of molecular sciences》2015,16(2):3677-3699
ALG-2, a 22-kDa penta-EF-hand protein, is involved in cell death, signal transduction, membrane trafficking, etc., by interacting with various proteins in mammalian cells in a Ca2+-dependent manner. Most known ALG-2-interacting proteins contain proline-rich regions in which either PPYPXnYP (type 1 motif) or PXPGF (type 2 motif) is commonly found. Previous X-ray crystal structural analysis of the complex between ALG-2 and an ALIX peptide revealed that the peptide binds to the two hydrophobic pockets. In the present study, we resolved the crystal structure of the complex between ALG-2 and a peptide of Sec31A (outer shell component of coat complex II, COPII; containing the type 2 motif) and found that the peptide binds to the third hydrophobic pocket (Pocket 3). While amino acid substitution of Phe85, a Pocket 3 residue, with Ala abrogated the interaction with Sec31A, it did not affect the interaction with ALIX. On the other hand, amino acid substitution of Tyr180, a Pocket 1 residue, with Ala caused loss of binding to ALIX, but maintained binding to Sec31A. We conclude that ALG-2 recognizes two types of motifs at different hydrophobic surfaces. Furthermore, based on the results of serial mutational analysis of the ALG-2-binding sites in Sec31A, the type 2 motif was newly defined. 相似文献
36.
Soichi Kugimiya Takeshi Shimoda Jun Tabata Junji Takabayashi 《Journal of chemical ecology》2010,36(6):620-628
Females of the solitary endoparasitoid Cotesia vestalis respond to a blend of volatile organic compounds (VOCs) released from plants infested with larvae of their host, the diamondback
moth (Plutella xylostella), which is an important pest insect of cruciferous plants. We investigated the flight response of female parasitoids to the
cruciferous plant Brassica rapa, using two-choice tests under laboratory conditions. The parasitoids were more attracted to plants that had been infested
for at least 6 hr by the host larvae compared to intact plants, but they did not distinguish between plants infested for only
3 hr and intact plants. Although parasitoids preferred plants 1 and 2 days after herbivory (formerly infested plants) over
intact plants they also preferred plants that had been infested for 24 hr over formerly infested plants. This suggests that
parasitoids can distinguish between the VOC profiles of currently and formerly infested plants. We screened for differences
in VOC emissions among the treatments and found that levels of benzyl cyanide and dimethyl trisulfide significantly decreased
after removal of the host larvae, whereas terpenoids and their related compounds continued to be released at high levels.
Benzyl cyanide and dimethyl trisulfide attracted parasitoids in a dose-dependent manner, whereas the other compounds were
not attractive. These results suggest that nitrile and sulfide compounds temporarily released from plants under attack by
host larvae are potentially more effective attractants for this parasitoid than other VOCs that are continuously released
by host-damaged plants. 相似文献
37.
Furukawa S Narisawa N Watanabe T Kawarai T Myozen K Okazaki S Ogihara H Yamasaki M 《International journal of food microbiology》2005,102(1):107-111
Effects of the clumping of bacterial spores on their heat resistance as a result of heat treatment were investigated. Spore suspensions of Bacillus cereus, Bacillus coagulans and Bacillus licheniformis were heated at 85 degrees C. Survivor curves of the three strains showed tailing in all treatments after 30 min. As the treatment time increased, the formation of spore clumps increased in all strains after 20 min. Relative hydrophobicity of the spore surface increased as a result of heat treatment. The effect of spore concentration on the inactivation of the B. licheniformis spores was investigated, and surviving curves showed no tailing below a concentration of 4.9 log CFU/ml. 相似文献
38.
Masao Kubo Takashi Matsubara Satoshi Shimizu Hiroshi Sato 《Artificial Life and Robotics》2010,15(2):207-211
In this article, a new localization approach for a team of robots that use the emergent properties of their formation is proposed.
Synchronized behavior sometimes generates spin-off effects that include geometric patterns. The question then arises as to
whether it is possible to use these patterns for something important for robots. In this article, Takayama’s control strategy,
which is a target enclosure formation, is discussed. A simple and useful expansion of Monte Carlo localization by the emergent
pattern is proposed. The proposed algorithms are confirmed through a series of computer simulations. 相似文献
39.
W. Shin T. Nakashima M. Nishibori T. Itoh N. Izu I. Matsubara Y. Nakagawa A. Yamamoto H. Obara 《Journal of Electronic Materials》2011,40(5):817-822
The performance of a microcombustor thermoelectric generator device based on a thermopile using p-type Bi0.3Sb1.7Te3 (BST) and n-type Pt films has been investigated. The BST films were prepared by two different methods—pulsed laser deposition (PLD) and
sputter deposition—on Si3N4/SiO2 multilayers on Si substrate. The ceramic catalyst combustor was patterned on the thermopile end on a thin membrane fabricated
by back-side bulk etching of the silicon substrate. At 138°C the thermoelectric power factors of the PLD and sputter-deposited
films were 3.6 × 10−3 W/mK2 and 0.22 × 10−3 W/mK2, respectively. The power from the generator with the sputter-deposited film was 0.343 μW, which was superior to that of the device with the PLD film, which provided 0.1 μW, for combustion of a 200 sccm flow of 3 v/v% hydrogen in air. 相似文献
40.