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11.
Dziuba Szymon Cierniak-Emerych Anna Michalski Grzegorz Poulová Petra Mohelská Hana Klímová Blanka 《Universal Access in the Information Society》2021,20(1):171-178
Universal Access in the Information Society - It is generally accepted that it is young people who are particularly interested in information and communication technologies (ICT). Older adults... 相似文献
12.
This paper analyses horizontal and vertical price dynamics in the EU petroleum markets. The results indicate that the cross-country price differentials have significant impact on the local price adjustments. We investigate the cross-national price spill-overs and find that the extent of the welfare transfer due to asymmetric price transmission, when analysed in a cross-country setting, is less pronounced than claimed in previous contributions in this area. We also find empirical evidence, although indirect, for the politically charged concept of “fuel tourism”, using a pan-European cross-product time series dataset. 相似文献
13.
Tomasz Tuzimski Szymon Szubartowski Aleksandra Stupak Wojciech Kwaniewski Magorzata Szultka-Myska Anna Kwaniewska Bogusaw Buszewski 《International journal of molecular sciences》2023,24(1)
The present study aimed to investigate the relationship between the concentrations of bisphenols residues in the amniotic fluid (AF) samples collected during amniocentesis and fetal chromosomal abnormalities in pregnant women. A total of 33 pregnant Polish women aged between 24 and 44 years, and screened to detect high risk for chromosomal defects in the first trimester, were included in this study. Samples were collected from these patients during routine diagnostic and treatment procedures at mid-gestation. The concentrations of various bisphenols residues in the samples were determined by liquid chromatography coupled with triple quadrupole tandem mass spectrometry (LC-ESI-QqQ-MS/MS). Residues of eight analytes (BPS, BPF, BPA, BPAF, BADGE, BADGE•2H2O, BADGE•H2O•HCl and BADGE•2HCl) were detected in amniotic fluid samples in the range 0.69 ng/mL to 3.38 ng/mL. Fetuses with chromosomal abnormalities showed a slightly higher frequency of occurrence of selected bisphenols residues in the AF samples collected between 15–26 weeks of pregnancies. Finally, the proposed method was applied in the simultaneous determination of several endocrine-disrupting chemicals from bisphenol group in 33 human AF samples. BADGE•H2O•HCl has been identified in the AF samples taken from women older than average in the examined group. The number of detected compounds has been significant for the following analytes: BPS, BPAF, BADGE•H2O•HCl and BADGE. The proposed method may be an attractive alternative for application in large-scale human biomonitoring studies. 相似文献
14.
Magda Aleksandra Pawlicka Szymon Zmorzyski Sylwia Popek-Marciniec Agata Anna Filip 《International journal of molecular sciences》2022,23(20)
This study aimed to evaluate the safety and potential use of soy isoflavones in the treatment of skin problems, difficult-to-heal wounds and postoperative scars in women after the oncological treatment of breast cancer. The effects of different concentrations of genistein as a representative of soy isoflavonoids on MCF-7 tumor cells and BJ skin fibroblasts cultured in vitro were assessed. Genistein affects both healthy dermal BJ fibroblasts and cancerous MCF-7 cells. The effect of the tested isoflavonoid is closely related to its concentration. High concentrations of genistein destroy MCF-7 cancer cells, regardless of the exposure time, with a much greater effect on reducing cancer cell numbers at longer times (48 h). Lower concentrations of genistein (10 and 20 μM) increase the abundance of dermal fibroblasts. However, higher concentrations of genistein (50 μM and higher) are detrimental to fibroblasts at longer exposure times (48 h). Our studies indicate that although genistein shows high potential for use in the treatment of skin problems, wounds and surgical scars in women during and after breast cancer treatment, it is not completely safe. Introducing isoflavonoids to treatment requires further research into their mechanisms of action at the molecular level, taking into account genetic and immunological aspects. It is also necessary to conduct research in in vivo models, which will allow for eliminating adverse side effects of therapy. 相似文献
15.
Jerzy?W.?Grzymala-BusseEmail author Jerzy?Stefanowski Szymon?Wilk 《Journal of Intelligent Manufacturing》2005,16(6):565-573
Our objective is a comparison of two data mining approaches to dealing with imbalanced data sets. The first approach is based
on saving the original rule set, induced by the LEM2 (Learning from Example Module) algorithm, and changing the rule strength
for all rules for the smaller class (concept) during classification. In the second approach, rule induction is split: the
rule set for the larger class is induced by LEM2, while the rule set for the smaller class is induced by EXPLORE, another
data mining algorithm. Results of our experiments show that both approaches increase the sensitivity compared to the original
LEM2. However, the difference in performance of both approaches is statistically insignificant. Thus the appropriate approach
for dealing with imbalanced data sets should be selected individually for a specific data set. 相似文献
16.
Katarzyna Tokarczyk-Dorociak Jan K. Kazak Haładyj Anna Szymon Szewrański Małgorzata Świąder 《影响评估与项目评价》2019,37(3-4):279-291
The paper presents the results of an evaluation of the effectiveness of SEA obtained as a result of a survey with the participation of stakeholders. In Poland, several hundred SEAs are conducted annually at the local and regional levels and several at the national level. Although the survey demonstrated that SEA is evaluated as effective or quite effective, the respondents pointed to several irregularities in the non-procedural dimension of effectiveness. The main ones in terms of substantive effectiveness are that SEA is rarely used to help develop plans/programmes and procedures are highly politicised. Moreover, low effectiveness in terms of variant assessment and cumulative impacts and nearly non-existent monitoring of the actual effects of implementing plans/programmes influence substantive effectiveness significantly. The respondents pointed to the problem resulting from the fact that plan-makers are unwilling to take into account the SEA recommended changes. They also emphasised that there are certain attempts to put pressure on SEA consultants to make the conclusions less stringent. Respondents indicate that in Poland the costs associated with conducting SEA often outweigh the profits. The research shows that the society is properly informed about SEA, but public involvement is still low. 相似文献
17.
Katarzyna Tokarczyk-Dorociak Jan K. Kazak Szymon Szewrański Anna Haładyj Łukasz Szkudlarek Grzegorz Chrobak 《影响评估与项目评价》2019,37(2):150-164
Guidelines and instructions for Environmental Impact Assessment and Strategic Environmental Assessment (together referred to as EA here) are developed to improve the quality of legal requirements’ implementation and to support EA procedure accomplishment. However, to date, it has not been checked whether they are useful for practitioners. Therefore, the aim of the study underlying this paper was to verify, based on the experience of Polish EA experts, whether guidelines and instructions are useful in their everyday work. A qualitative study comprising of a questionnaire survey and interviews tested whether (1) EA practitioners know and use the Polish and EU guidelines, (2) how EA practitioners evaluate the validity and usefulness of such instructions, and (3) in which areas there is a lack of instructions and guidelines. The results show a low level of knowledge of national and EU handbooks. Those guidelines focusing on legal procedures, road investments and designing animal passageways are considered to be the most useful. Moreover, practitioners indicate that EU guidelines should be translated into Polish. Most important for practitioners is the linking of guidelines with the EA procedure, so that they can become a platform for dialogue of all stakeholders. 相似文献
18.
Tomczak Jakub M. Zaręba Szymon Ravanbakhsh Siamak Greiner Russell 《Neural Processing Letters》2019,50(2):1401-1419
Neural Processing Letters - This paper introduces a new approach to maximum likelihood learning of the parameters of a restricted Boltzmann machine (RBM). The proposed method is based on the... 相似文献
19.
Sampling (evenly) the suffixes from the suffix array is an old idea trading the pattern search time for reduced index space. A few years ago Claude et al. showed an alphabet sampling scheme allowing for more efficient pattern searches compared with the sparse suffix array, for long enough patterns. A drawback of their approach is the requirement that sought patterns need to contain at least one character from the chosen subalphabet. In this work, we propose an alternative suffix sampling approach with only a minimum pattern length as a requirement, which is more convenient in practice. Experiments show that our algorithm (in a few variants) achieves competitive time‐space tradeoffs on most standard benchmark data. Copyright © 2017 John Wiley & Sons, Ltd. 相似文献
20.
We present a simple q‐gram based semi‐index, which allows to look for a pattern typically only in a small fraction of text blocks. Several space‐time tradeoffs are presented. Experiments on Pizza & Chili datasets show that our solution is up to three orders of magnitude faster than the Claude et al. (Journal of Discrete Algorithms 2012; 11 :37) semi‐index at a comparable space usage. Moreover, the construction of our data structure is fast and easily parallelizable. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献