On cross-modal similarity: Auditory–visual interactions in speeded discrimination.

A series of four experiments explored how cross-modal similarities between sensory attributes in vision and hearing reveal themselves in speeded, two-stimulus discrimination. When subjects responded differentially to stimuli on one modality, speed and accuracy of response were greater on trials accompanied by informationally irrelevant "matching" versus "mismatching" stimuli from the other modality. Cross-modal interactions appeared in (a) responses to dim/bright lights and to dark/light colors accompanied by low-pitched/high-pitched tones; (b) responses to low-pitched/high-pitched tones accompanied by dim/bright lights or by dark/light colors; (c) responses to dim/bright lights, but not to dark/light colors, accompanied by soft/loud sounds; and (d) responses to rounded/sharp forms accompanied by low-pitched/high-pitched tones. These results concur with findings on cross-modal perception, synesthesia, and synesthetic metaphor, which reveal similarities between pitch and brightness, pitch and lightness, loudness and brightness, and pitch and form. The cross-modal interactions in response speed and accuracy may take place at a sensory/perceptual level of processing or after sensory stimuli are encoded semantically. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A new method for the control of the river Nile

This paper introduces a new stochastic control method, Extended Linear Quadratic Gaussian control, that appears to be particularly promising for the management of complex reservoir configurations such as the River Nile system. The method is introduced by means of a short case study related to the regulation of the Equatorial Lakes in the Nile basin. If the necessary data are available, the method can be easily adapted to the entire Nile system and used to investigate a variety of management issues.     

The impact of cross-training on team effectiveness.

The authors examined the role of cross-training in developing shared team-interaction mental models, coordination, and performance in a 2-experiment study using computer simulation methodology (for Experiment 1, N=45 teams; for Experiment 2, N=49 teams). Similar findings emerged across the 2 experiments. First, cross-training enhanced the development of shared team-interaction models. Second, coordination mediated the relationship between shared mental models and team performance. However, there was some inconsistency in the findings concerning the depth of cross-training necessary for improving shared mental models. Results are discussed in terms of the impact of different levels of cross-training on team effectiveness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Collapsed spring observations in arson investigations: A critical metallurgical evaluation

Observation of collapsed coiled (steel) furniture springs has been utilized for several decades or more by arson investigators as an indicator of whether an accelerant or smoldering source (such as a cigarette) caused a fire. This paper cites the contradictory literature, synopsizes metallurgical phenomena operative when coiled steel springs are subjected to fires, and presents empirical data from U.S. Federal Bureau of Investigation (FBI) Laboratory testing. It is concluded that observation of the collapsed state of coiled furniture/bedding springs is not a reliable indicator of whether a fire was initiated by a smoldering cigarette or accelerated by the presence of a hydrocarbon.     

Redirecting effector T cells through their IL-2 receptors

Fusion proteins constructed of a tumor-specific Ab joined to IL-2 (Ab-IL-2) have been used in the past to deliver cytokine directly to the site of tumor cells in vivo. These molecules mimic the activity of IL-2 and assist in activating and expanding antitumor effector cells. To enhance the cytolytic activity of CTL specific for peptide epitopes of the Her-2/neu tumor Ag presented by HLA-A*0201 molecules, a fusion protein was constructed consisting of a single chain Ab specific for Her-2/neu, linked to IL-2 (neu-Ab-IL-2). When added to a mixture of tumor cells and Her-2/neu-specific CTL, the protein was found to augment lysis of tumor cells. In addition, the hybrid molecule also promoted lysis of Her-2/neu expressing tumors by non-tumor-specific cloned T cell lines, including Th1 CD4 cells. Analysis of the mechanism of cytotoxicity revealed that the fusion protein mediates the formation of stable conjugates between T cells expressing IL-2R and tumor cells expressing Her-2/neu, resulting in lysis through the Fas-Fas ligand pathway. Lysis induction was independent of specific engagement by the TCR. When tested for its ability to enhance tumor cell eradication by Her-2/neu-specific CD8+ T cells in an adoptive transfer model in SCID mice, neu-Ab-IL-2 facilitated the elimination of tumor cells in vivo. Surprisingly, the combination of non-tumor-specific CD8+ T cells and fusion protein also induced a significant delay of tumor growth. This represents a novel approach for redirecting non-tumor-specific T cells to eliminate tumors.     

Maximum zeros scheduling for satellite switch TDMA

A scheduling technique suitable for preassignment in satellite switched time division multiple access (SS-TDMA) systems is presented. As many uninterrupted bursts as are feasible are transmitted per configuration of the switch matrix. For small switch matrices (up to 6*6) this technique usually requires fewer reconfigurations than previous methods.<>