Synthesis and biological activity of novel thiazolidinediones

Novel compounds having a dual pharmacophore were synthesised and evaluated for their insulin sensitiser and anti-inflammatory properties in different animal models.     

Electrical Properties of 6H-BaTi0.95M0.05O3−δ Ceramics where M = Mn, Fe, Co and Ni

Hexagonal BaTiO₃ materials have been stabilised at room temperature according to the formula BaTi_0.95M_0.05 O_3– where M = Mn, Fe, Co and Ni. Dense ceramics (> 96% of the theoretical X-ray density) were sintered at 1450C in flowing O₂ gas from calcined powders prepared by the mixed oxide route at 1300C. All samples were single-phase and the bulk conductivity, _b, measured by Impedance Spectroscopy and Q.f measured by microwave dielectric resonance methods showed a strong dependence on the type of dopant. _b at 300C was 10^–7, 10^–5.5, 10^–5.5 and 10^–4 Scm^–1 for M = Mn, Fe, Ni and Co, respectively and Q.f at 5 GHz was 7790, 6670, 2442 and 1291 GHz, for M = Mn, Fe, Ni and Co, respectively. The correlation between _b and Q.f is attributed to the presence of oxygen vacancies and/or mixed valency of the dopant ions.     

Precipitation hardening of Cu-4Ti-1Cd alloy

Precipitation hardening of Cu-4Ti-1Cd alloy has been studied using hardness measurements and transmission electron microscopy. This alloy exhibited hardness of 238 Hv in solution treated (ST) condition and attained peak hardness of 318 Hv after ageing at 450°C for 40 h. Electrical conductivity of Cu-4Ti-1Cd alloy increased from 5.7 %IACS (International Annealed Copper standard) in ST condition to 8.9 %IACS on ageing at 450°C for 16 h. This alloy exhibited markedly higher yield strength (751 MPa in the peak-aged condition) compared to Cu-4.5Ti alloy but the increase in UTS due to cadmium addition was less significant. The higher yield strength of ternary alloy in peak aged condition is due to the solid solution strengthening of cadmium as well as the presence of -Cu₄Ti precipitate. On over-ageing the alloy showed a decrease in hardness as a result of formation of equilibrium precipitate, -Cu₃Ti. Optical microscopy reveals single phase with equiaxed grains in solution treated condition. A coherent, metastable phase -Cu₄Ti is responsible for high strength and hardness in peak aged condition. The over-ageing in this alloy shows the formation of cellular structure at the grain boundaries of the matrix phase.     

Rolling and recrystallisation textures in Cu–Al,Cu–Mn and Cu–Ni alloys

The development of strongly cube textured Cu based substrates is important in the cost effective production of long lengths of high temperature superconducting cables. The present paper reports textures (deformation and recrystallisation) development in pure Cu, Cu–Al, Cu–Mn (with a solute content of 1–3 at.%) and Cu–35 at.% Ni alloys.     

Impacts of reservoirs on groundwater and vegetation: A study based on remote sensing and GIS techniques

Suspended sediment is an important parameter for the monitoring of water quality, water movement, erosion, and deposition. Quantitative suspended sediment concentrations have been identified through the analysis of remotely sensed airborne multi-spectral video imagery. From a statistical analysis of the data, a single band ( 675-725 nm) was shown to be sufficient for determining suspended sediment concentrations within lakes of the Mackenzie Delta, N.W.T., Canada. A statistical analysis and derived linear regression equation were used to quantitatively determine suspended sediment concentrations for a number of lakes within the Mackenzie Delta. The results were compared with a qualitative interpretation of simultaneous colour photography. The multi-spectral video imagery proved to have superior suspended sediment concentration resolution characteristics.     

GIS based surface hydrological modelling in identification of groundwater recharge zones

Digital elevation model (DEM) is a storehouse of a variety of hydrological information along with terrain characteristics. In recent years, automatic extraction of drainage network from DEM with the help of Geographical Information System (GIS) has become possible and is now being practised the world over for hydrological studies. In the present study, a comparative analysis of the drainage network derived from DEM and drainage extracted from surveyed topographical maps has been carried out. A comparative analysis based on nearest neighbour analysis on an intersection theme of two drainage networks showed that there is clustering (randomness<1) existing at places which show potential groundwater recharge zones. The suitable groundwater recharge zones identified in the drainage comparative analysis also show good correlation with the suitable recharge maps derived from remote sensing and GIS based procedure. In this study, two different watersheds (a) Dwarkeshwar in Bankura district, West Bengal, India, and (b) Kethan in Vidisha districts of Madhya Pradesh, India have been taken to analyse for identification of suitable groundwater recharge zones. The drainage comparative analysis approach developed and tested successfully in the present study is quick and reliable for the identification of suitable groundwater recharge zones particularly in a hard rock terrain.     

Optimal coverage of an infrastructure network using sensors with distance-decaying sensing quality

Motivated by recent applications of wireless sensor networks in monitoring infrastructure networks, we address the problem of optimal coverage of infrastructure networks using sensors whose sensing performance decays with distance. We show that this problem can be formulated as a continuous p-median problem on networks. The literature has addressed the discrete p-median problem   on networks and in continuum domains, and the continuous p$p$-median problem in continuum domains extensively. However, in-depth analysis of the continuous p$p$-median problem on networks has been lacking. With the sensing performance model that decays with distance, each sensor covers a region equivalent to its Voronoi partition on the network in terms of the shortest path distance metric. Using Voronoi partitions, we define a directional partial derivative of the coverage metric with respect to a sensor’s location. We then propose a gradient descent algorithm to obtain a locally optimal solution with guaranteed convergence. The quality of an optimal solution depends on the choice of the initial configuration of sensors. We obtain an initial configuration using two approaches: by solving the discrete p$p$-median problem on a lumped   network and by random sampling. We consider two methods of random sampling: uniform sampling and D²$D^2$-sampling. The first approach with the initial solution of the discrete p$p$-median problem leads to the best coverage performance for large networks, but at the cost of high running time. We also observe that the gradient descent on the initial solution with the D²$D^2$-sampling method yields a solution that is within at most 7% of the previous solution and with much shorter running time.     

Development of an Online Heat Index Measurement System for Thermal Comfort Determination

This paper presents the development of a reliable heat index (HI) measurement system for evaluating the thermal comfort of a particular building or a particular area. The HI is an index that combines air temperature and relative humidity (RH) to determine the human-perceived equivalent temperature. To measure the air temperature and RH, temperature to digital converter and RH to voltage converter is used. HI is calculated online with the help of embedded firmware of the microcontroller. This calculated value is then transferred to the computer through standard RS 232 serial port. The same sensor node is tested with the RS 485 network standard by changing the transceiver of the node. The system is calibrated using four standard saturated binary salt solutions.