Adaptive antennas for MIMO OFDM‐CDMA communication systems

In this paper, we propose symbol‐based receivers for orthogonal frequency division multiplexing (OFDM) code‐division multiple‐access (CDMA) multiple‐input‐multiple‐output (MIMO) communications in multipath fading channels. For multiuser and multipath fading environments, both intersymbol interference and multiple‐access interference must be considered. We propose narrowband and wideband antennas and Wiener code filter for MIMO OFDM‐CDMA systems. The proposed receivers are updated symbol‐by‐symbol to achieve low computational complexity. Simulation results show that the proposed Wiener code filter can improve the system performance for the proposed adaptive antennas. The wideband antenna can achieve better error‐rate performance than that of the narrowband antenna when multipath effect exists. The convergence rate of the recursive least squares antennas is faster than that of the least mean square antennas. Copyright © 2013 John Wiley & Sons, Ltd.     

Coupled Shear Strain-Pore Pressure Responses of Soil in Shaking Table Tests

Shaking table tests on a saturated sand specimen in a laminar shear box were performed to measure the coupled shear strain-pore pressure response of sands subjected to horizontal shaking. Three methods of shear strain evaluation techniques, which use soil motions recorded by embedded sensors within the soil specimen and external sensors on frame, were utilized to evaluate the shear strain-time histories in one-dimensional shaking cases. Coupled shear strain-pore pressure responses throughout the liquefaction process are presented based on evaluated shear strains and measured pore pressures at corresponding depths. More insights of the interactions between the induced shear strain and generated excess pore pressure are also given, including the temporal variations of induced shear strain prior and after the initial liquefaction, development of liquefied zone, and duration of liquefaction state. These spatial and temporal variations of coupled responses reveal that the induced shear strain amplitude is not only an important property in triggering soil liquefaction but also a better index in defining the time of initial liquefaction. Identifications of these coupled features will be beneficial for verifying and interpreting testing data in physical modelling for liquefaction studies.     

Effect of high intensity drive train stimulation on dispersion of atrial refractoriness: role of autonomic nervous system

OBJECTIVES: This study evaluated the effect of high intensity drive train (S1) stimulation on the atrial effective refractory period (ERP) and its relation to the autonomic nervous system. BACKGROUND: High intensity S1 stimulation was demonstrated to shorten the ventricular ERP and to increase dispersion of refractoriness. These effects may be due to local release of neurotransmitters. The response of the atrium and ventricle to neurotransmitters was different. The effects of high intensity S1 stimulation at the atrial tissue were evaluated. METHODS: Forty patients without structural heart disease were studied. In group 1, 20 patients, the atrial ERP was measured at 0, 7, 14, 21 and 28 mm away from the S1 site under both twice diastolic threshold and high intensity (10 mA) S1 stimulation. The same protocol was repeated after sequential administration of propranolol (0.2 mg/kg body weight) and atropine (0.04 mg/kg). In group 2, the other 20 patients, the atrial ERP was studied at three atrial sites (high lateral right atrium [HLRA], right posterior interatrial septum [RPS] and distal coronary sinus [DCS] with twice diastolic threshold and high intensity S1 stimulation at baseline and after sequential autonomic blockade. The three atrial sites were randomly assigned as the S1 location. RESULTS: In group 1, high intensity S1 stimulation shortened the atrial effective refractory period most prominently at the site of S1: (mean +/- SD) 13.3 +/- 6.4% (p < 0.001), 8.1 +/- 3.8% (p < 0.001), 4.8 +/- 4.3% (p < 0.001), 3.7 +/- 4.7% (p < 0.001) and 0.5 +/- 2.6% at 0, 7, 14, 21 and 28 mm from the S1 site, respectively. The effect of high intensity S1 stimulation was blunted with propranolol and autonomic blockade but persisted after atropine alone. High intensity S1 stimulation also increased dispersion of refractoriness (from 23 +/- 11 ms to 31 +/- 12 ms, p = 0.01), which was eliminated with autonomic blockade. In group 2, high intensity S1 stimulation had similar effects at different locations (ERP shortening of 10.8 +/- 2.7%, 10.8 +/- 2.2% and 12.2 +/- 4.6% at the HLRA, RPS and DCS, respectively). The responses to sequential autonomic blockade were similar to those in group 1. However, high intensity S1 stimulation at HLRA increased dispersion of refractoriness, but at DCS it reduced dispersion of refractoriness. CONCLUSIONS: High intensity S1 stimulation led to local shortening of the atrial ERP and increased dispersion of refractoriness. These effects were blunted with propranolol and autonomic blockade. High intensity S1 stimulation at the HLRA increased dispersion of atrial refractoriness, whereas the same stimulation at the DCS decreased dispersion of atrial refractoriness.     

Induction of cytochrome P450 1A in hamster liver and lung by 6-nitrochrysene

The present study has determined the effect of 6-nitrochrysene (6-NC) on hepatic and pulmonary cytochrome P450 (P450)-dependent monooxygenases using hamsters pretreated with the nitrated polycyclic aromatic hydrocarbon (nitro-PAH) at 5 mg/kg per day for 3 days. Pretreatment with 6-NC elevated serum gamma-glutamyltranspeptidase, lactate dehydrogenase, and bilirubin levels. Liver S9 fractions prepared from controls and hamsters pretreated with 6-NC markedly increased mutagenicity of the nitro-PAH in Salmonella typhimurium tester strains TA98, TA100, and TA102. The pretreatment selectively increased 1-nitropyrene reductase activities of lung cytosol and liver and lung microsomes. Pretreatment with 6-NC resulted in increases of microsomal 7-ethoxyresorufin and methoxyresorufin O-dealkylases activities in liver and lung without affecting the monooxygenase activities in kidney. Immunoblot analysis of microsomal proteins using mouse monoclonal antibody 1-12-3 to rat P450 1A1 revealed that 6-NC induced P450 1A-immunorelated proteins in liver and lung. RNA blot analysis using mouse P450 1A1 cDNA showed that 6-NC increased liver and lung P450 1A mRNA. 6-NC had no effect on the kidney P450 protein and mRNA. The present study demonstrates that the hamster enzymes can support 6-NC metabolic activation and the nitro-PAH induces liver and lung P4501A via a pretranslational mechanism.     

Performance analysis of two echo control designs in ATM networks

An ATM call interworking with the public switched telephone network may experience echo problems due to impedance mismatch. The authors propose two echo control designs to assure the quality of voice services by reducing round-trip echo delay. Performance of these two echo control designs is then analyzed     

Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes

The oxidation of benzo[a]pyrene (B[a]P) was examined using reconstituted systems prepared with recombinant human cytochrome P450 (P450) enzymes 1A1, 1A2, 2C8, 2C10, 2E1, and 3A4 and with microsomes prepared from Saccharomyces cerevisiae expressing recombinant human P450s 2C8, 2C9, and 2C18. Products measured by HPLC included the 3- and 9-phenols, the 4,5-, 7,8-, and 9,10-dihydrodiols (detected in the presence of epoxide hydrolase), and products in the polar fraction eluting immediately after the void volume. The most active enzyme in all reactions was P450 1A1. P450 3A4 and P450 1A2 formed appreciable amounts of several of the products, including the 3-phenol. P450 2C enzymes and P450 2E1 formed relatively low amounts of all B[a]P products. Consideration of these patterns along with knowledge of levels of expression of the P450s in human tissues and previous results with microsomes leads to the conclusion that P450 1A1 should dominate the oxidation of B[a]P in tissues where it is present and inducible. In human liver the level of P450 1A1 is low and P450 3A4, P450 2C subfamily enzymes, and P450 1A2 probably all contribute. Of the human P450s considered here, P450 1A2 was the most active hepatic enzyme forming the 7,8-dihydrodiol. 7,8-Benzoflavone stimulated the oxidation of B[a]P by P450 3A4 and inhibited the oxidations catalyzed by P450 1A2. The extent of inhibition of P450 1A1 was less (than with P450 1A2), probably due to the rapid oxidation of 7,8-benzoflavone by P450 1A1. The major 7,8-benzoflavone product appears to be the 5,6-oxide.     

直接发酵木糖为酒精的新酵母基因工程菌的选育

裂殖酵母,Schizosacchatomyces porebe不能发酵木糖,也不能用它来增殖细胞。但是,这种酵母能发酵木酮糖为酒精,产率和转化率都很高。这表明,它缺少异构酶基因,如果将其它微生物的这种基因克隆到酵母中去,它就能直接发酵木糖。本文介绍了Schizosaceh.porebe的五碳糖磷酸代谢途径,这种代谢途径使得它成为用于这一目的的理想菌株。含有异构酶基因的DNA片段来自Clark和Carbon的大肠杆菌基因库,它的大小为2.4kb,PstⅠ-抗性。将这个基因克隆到上述酵母中去,得到的酵母基因工程菌株不仅能利用木糖作为唯一碳源和能源,还能发酵木糖为酒精,它具有在工业上应用的潜力     

Performance analysis of adaptive receivers for DS/CDMA communication systems

Both intersymbol interference (ISI) and multiple-access interference (MAI) are the important issues in code division multiple access (CDMA) multiuser communication systems. The step size of the traditional least-mean-square (LMS) adaptive receivers must be substantially adjusted to overcome the effect due to different channel responses or different numbers of active users. The normalized-LMS (NLMS) algorithm can automatically manipulate the adjustment to avoid the problem just discussed. This paper proposes the symbol-based interference rejection filter with NLMS algorithm and derives both finite impulse response (FIR)- and infinite impulse response (IIR)-type algorithms. We also derive the optimal step sizes and minimum mean-square errors (MSEs) for both the FIR and IIR symbol-based receivers. The complexity of our proposed FIR receiver is lower than that of the conventional chip-based receivers. In addition, it is shown that the bit error rate performance of our proposed symbol-based receivers is superior to conventional one in the simulations. Simulations also show the correctness of our theoretical analysis of minimum MSE. Copyright © 2008 John Wiley & Sons, Ltd.     

Performances of OFDM‐CDMA receivers with MIMO communications

This paper considers the joint design of OFDM and code division multiple access (CDMA) with MIMO communications. The receivers for both Bell Labs Layered Space Time system and space–time block code are designed in this paper. The performances of the MIMO‐OFDM‐CDMA receivers are investigated in several typical fading channels. The maximum likelihood, zero forcing, and minimum mean square error receivers for the MIMO‐OFDM‐CDMA systems are derived, and the performances in the typical fading channels are verified by the simulations. Copyright © 2012 John Wiley & Sons, Ltd.