晶须取向对SiCw／Al复合材料切削表面质量的影响

切削与晶须取向方向间的夹角对ＳｉＣｗ／Ａｌ复合材料切削表面质量有很大影响。当切削角为４５°时，晶须拔出和转动现象均较少，复合材料切削表面粗糙度最低。当切削角为１３５度时，晶段转动造成的撕裂破坏程度很大，复合材料切削表面粗糙度最大。     

高温超导研究的新进展

本文简要回顾了一年来高温超导的新进展，特别介绍和讨论了新型高温超导体系和线材、带材、块材及薄膜应用的发展情况。     

Termination of pregnancy at 9-13 weeks' amenorrhoea with mifepristone and misoprostol

The effectiveness of a combined regimen of mifepristone and vaginal misoprostol for termination of pregnancies of 9-13 weeks of gestation was investigated in 120 UK abortion patients (median age, 22.1 years; median duration of amenorrhea, 10.3 weeks). Each woman received a single oral dose of 200 mg of mifepristone 36-48 hours before admission, at which time 800 mcg of misoprostol was administered vaginally. Where indicated, a further two doses of 400 mcg of misoprostol (vaginal or oral) were provided every 3 hours. All 120 women aborted on the day of prostaglandin administration; however, 6 women (5%) required exploratory curettage after the procedure for retained placenta. The median prostaglandin dose was 1200 mcg (range, 800-1600 mcg). The median time from misoprostol administration to abortion was 4.33 hours (range, 1.3-16.0 hours). 60 women (50%) required oral analgesics and 26 (22%) received parenteral analgesia. Diarrhea occurred in 38 women (32%). The median duration of bleeding after abortion was 12.5 days (range, 3-43 days). In questionnaires administered to 73 women, only 3 (4%) expressed dissatisfaction with medical abortion, because of pain or prolonged bleeding. The relatively high dose of misoprostol used in this study and the vaginal route of administration are presumed to account for the 95% success rate. Extension of medical abortion to later gestation times would decrease the need for surgery and expand women's choice of methods of pregnancy termination.     

李子溪流域水土流失及泥沙输移规律初步研究

为了探讨长江上游流域水土流失及泥沙输移规律，选取嘉陵江中游的支流李子溪为典型流域进行分析研究，在实地调查，野外测验及应用１９６０年－１９９１年实测降雨、径流、输沙资料的基础上，利用单因子相关分析和多因子回归分析，分别建立了输水利沙量、最大输沙率计算方程。在此基础上，参照径流瞬时单位线原理，以线性时不变系统为基础，建立输沙瞬时单位线模型。通过输沙单位线与时段净侵蚀量的卷积得到流域出口断面的输沙率过程     

煤矿许用毫秒延期电雷管研究

文中对影响煤矿许用毫秒延期电雷管沼气安全性与延期时间精度的因素进行了研究。应用正交设计研制了新的延期药配方，确定了合理的雷管结构及装配工艺参数，产品性能达到ＧＢ８０３１《工业电雷管》的规定。     

A study of self poisoning with oral salbutamol--laboratory and clinical features

A review of 35 patients > 60 years of age with odontoid fractures showed that a type II injury (Anderson and D'Alonso) was the most common fracture pattern (82% of cases). On the basis of mechanism of injury and sex incidence, we deduced that osteopenia is a contributory factor in the occurrence of odontoid fractures. A fall in a domestic setting was the cause in 53%. The peg was posteriorly displaced in 88% of type II fractures, and primary union occurred in 23%. The incidence of concomitant spinal cord injury with type II fractures was higher in older patients than it was in those < 60 years of age. The outcome for these patients was largely determined by their neurological status at presentation. Myelopathy as a late complication of nonunion was not observed in nine patients with an average follow-up of 21 months. The data suggest that vigorous attempts to secure both primary union and a sound arthrodesis for non-union are questionable in the elderly except in unusual circumstances.     

Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage

Amplification of genes involved in signal transduction and cell cycle control occurs in a significant fraction of human cancers. Loss of p53 function has been proposed to enable cells with gene amplification to arise spontaneously during growth in vitro. However, this conclusion derives from studies employing the UMP synthesis inhibitor N-phosphonacetyl-L-aspartate (PALA), which, in addition to selecting for cells containing extra copies of the CAD locus, enables p53-deficient cells to enter S phase and acquire the DNA breaks that initiate the amplification process. Thus, it has not been possible to determine if gene amplification occurs spontaneously or results from the inductive effects of the selective agent. The studies reported here assess whether p53 deficiency leads to spontaneous genetic instability by comparing cell cycle responses and amplification frequencies of the human fibrosarcoma cell line HT1080 when treated with PALA or with methotrexate, an antifolate that, under the conditions used, should not generate DNA breaks. p53-deficient HT1080 cells generated PALA-resistant variants containing amplified CAD genes at a frequency of >10(-5). By contrast, methotrexate selection did not result in resistant cells at a detectable frequency (<10(-9)). However, growth of HT1080 cells under conditions that induced DNA breakage prior to selection generated methotrexate-resistant clones containing amplified dihydrofolate reductase sequences at a high frequency. These data demonstrate that, under standard growth conditions, p53 loss is not sufficient to enable cells to produce the DNA breaks that initiate amplification. We propose that p53-deficient cells must proceed through S phase under conditions that induce DNA breakage for genetic instability to occur.     

Coordinating Agents in Shop Floor Environments From a Dynamic Systems Perspective

In this paper, we address agent coordination from a dynamic systems perspective and propose a dynamic coordination model, which is inspired by biological metabolic systems. A new coordination mechanism through dynamic local adjustment (CDLA) is presented, and coordination is achieved when every agent utilizes explicitly the global system dynamics and performs iteratively a dynamic local adjustment procedure. The CDLA mechanism is investigated in an example multiagent shop floor system. The results show that the example manufacturing process is well-coordinated and the coordination approach is practically applicable and effective     

A segmentation-based fine-grained peer sharing technique for delivering large media files in content distribution networks

Delivering large media files over the Internet is a challenging task because it has some unique features that are different from delivering conventional Web documents. In this paper, we propose a fine-grained peer sharing technique for dealing with the problem in the context of content distribution networks. The key difference of the technique from conventional peer-to-peer systems is that the unit of peer sharing is not a complete media file, but at a finer granularity. By doing so, we improve the flexibility of replica servers for handling client requests. We analyze the storage requirement at replica servers and design a scheduling algorithm to coordinate the delivery process from multiple replica servers to a client. Our simulations show that the fine-grained peer sharing approach can reduce the initial latency of clients and the rejection rate of the system significantly over a simple peer sharing method.     

大型对开组合齿圈工艺设计分析及其最优化

本文论述了大型齿圈的结构特征及其现行工艺的合理性；在建立工艺关键环节概念的基础上提出工艺优化方案。并从理论上论证了实现最优化的充分可能性。