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21.
When the underexpanded supersonic jet impinges on the obstacle, it is well known that the self-induced flow oscillation occurs at the specific condition of the pressure ratio in the flowfield, the position of an obstacle and so on. This oscillation is related with the noise problems of aeronautical and other industrial engineering so that the characteristic and the mechanism of self-induced flow oscillation have to be cleared to control the various noise problems. But, it seems that the characteristics of t... 相似文献
22.
New methods are proposed to estimate the effective delayed neutron fraction βeff in Monte Carlo calculations: the eigenvalue methods jointly used with the differential operator sampling and correlated sampling techniques. In particular, the eigenvalue method with the differential operator sampling technique has a distinct feature that it theoretically gives an exact βeff value. To verify the proposed methods, Monte Carlo calculations are performed for several systems with simple geometry. It is found that the results obtained with the proposed methods agree with the reference deterministic results within sufficiently small statistical uncertainties. The indirect perturbed source effect must be taken into account to estimate an exact βeff value. 相似文献
23.
Kikuo Wakino Hirohumi Sunahara Yasunobu Yoneda Yukio Sakabe Kimihide Sugo 《Integrated ferroelectrics》2013,141(3):269-282
Abstract Low temperature fired ceramics based on alumina/glass added oxide ceramics have been developed and are being used by several companies as substrates for high density assembled modular packaging.1–3 The features of low temperature fireable substrates are the cofireability with highly conductive metals such as Ag, Ag-Pd, or Cu, and the cofireability with other passive component materials for L, C, R and relatively low dielectric constant elements. But most of these substrates have the disadvantage that their thermal expansion coefficient is not perfectly compatible with Si or GaAs. This paper reports the results of a newly developed cordierite/glass based substrate employing Cu as the surface and internal conductors and having the freedom of tuning the thermal expansion coefficient by changing the composition. The ceramic composition with adjustable thermal expansion coefficient value of 3 to 7 ppm/°C can be manufactured and easily matched with the thermal expansion coefficient of Si or GaAs without a big change of electrical performance. 相似文献
24.
Yasunobu Yokomizu Masato Suzuki Toshiro Matsumura 《IEEJ Transactions on Electrical and Electronic Engineering》2006,1(3):268-275
The present paper reports fundamental properties of CF3I under high-temperature conditions to find out the usefulness of CF3I as an arc-quenching gas. Firstly, particle compositions of CF3I were theoretically calculated in a temperature range from 300 to 30 000 K. Secondly, thermodynamic, transport and radiation properties of the CF3I were also obtained for pressures 0.1–1.0 MPa. Finally, the transient process of a conductance of a residual arc in CF3I was derived to compare with those in other arc-quenching gases. In addition, an arc extinguishing capability of CF3I in a thermal re-ignition region was derived to find out whether CF3I shows a higher capability than CO2, N2 and air. © 2006 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献
25.
Daisuke Iioka Yasunobu Yokomizu Masuo Goto Toshiro Matsumura Hirotaka Shimizu 《IEEJ Transactions on Electrical and Electronic Engineering》2006,1(3):209-215
We investigated the required limiting impedance and capacity of a fault current limiter (FCL) installed at an incoming feeder of a customer system with a synchronous generator in a utility distribution system. It was assumed that two types of FCL were installed, i.e. a resistive type (R‐type) FCL and an inductive type (L‐type) FCL. A fault current out of the customer system and a voltage in the customer system were calculated following a three‐phase, short‐circuit fault occurrence. It was found that the required type of FCL and the required limiting impedance depended on the rated capacity of the generator in order to obtain the suppression of the fault current under 0.1 kAS and to maintain of customer voltage between 85 and 100% of the nominal voltage (6.6 kV). The capacity of FCL consisting of the smallest limiting impedance is discussed. © 2006 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献
26.
Dr. Atsushi Yoshimori Yasunobu Asawa Enzo Kawasaki Tomohiko Tasaka Seiji Matsuda Dr. Toru Sekikawa Satoshi Tanabe Dr. Masahiro Neya Dr. Hideaki Natsugari Dr. Chisato Kanai 《ChemMedChem》2021,16(6):955-958
Discoidin domain receptor 1 (DDR1) inhibitors with a desired pharmacophore were designed using deep generative models (DGMs). DDR1 is a receptor tyrosine kinase activated by matrix collagens and implicated in diseases such as cancer, fibrosis and hypoxia. Herein we describe the synthesis and inhibitory activity of compounds generated from DGMs. Three compounds were found to have sub-micromolar inhibitory activity. The most potent of which, compound 3 (N-(4-chloro-3-((pyridin-3-yloxy)methyl)phenyl)-3-(trifluoromethyl)benzamide), had an IC50 value of 92.5 nM. Furthermore, these compounds were predicted to interact with DDR1, which have a desired pharmacophore derived from a known DDR1 inhibitor. The results of synthesis and experiments indicated that our de novo design strategy is practical for hit identification and scaffold hopping. 相似文献
27.
Dr. Jens Sproß Dr. Yasunobu Yamashita Prof. Dr. Harald Gröger 《Chembiochem : a European journal of chemical biology》2020,21(14):1968-1971
Ion mobility spectrometry (IMS) coupled with mass spectrometry (MS) enables the investigation of protein folding in solution. Herein, a proof-of-concept for obtaining structural information about the folding of a protein in dependency of the amount of an organic cosolvent in the aqueous medium by means of this IMS-MS method is presented. By analyzing the protein with native nano-electrospray ionization IMS-MS, the impact of acetonitrile as a representative organic cosolvent and/or pH values on the folding of an enzyme was successfully evaluated in a fast and straightforward fashion, as exemplified for an ene reductase from Gluconobacter oxydans. The IMS-MS results are in agreement with findings from the nicotinamide adenine dinucleotide phosphate (NADPH)-based spectrophotometric enzyme activity tests under analogous conditions, and thus, also rationalizing these “wet” analytical data. For this ene reductase, a higher tolerance against CH3CN in the presence of a buffer was observed by both analytical methods. The results suggest that this IMS-MS methodology could be a useful complementary tool to existing methods in process optimization and fine-tuning of solvent conditions for biotransformations. 相似文献
28.
Koichi Sakita Kunio Takayama Kenji Awamoto Yasunobu Hashimoto 《Journal of the Society for Information Display》2003,11(1):139-144
Abstract— A simple model to calculate changes in wall voltage during weak discharge in three‐electrode ACPDPs was developed. A change in the wall voltage vector has an intrinsic direction for each discharge, which not only reveals the basis of problems in the ramp setup but also simplifies the analysis of cell operation during setup. New ramp‐setup waveforms designed for this model widened the operating margin. 相似文献
29.
In this study, four redundant systems having the parallel string configuration and the quad configuration consisting of 2n identical units are considered and the reliability of each system and MTBF (Mean Time Between Failures) are evaluated. Next, as the special case of the systems in this study, the case of four units corresponds to the Keene's system and MTBF of each system agreed with his results. Further, as the results evaluated MTBF relating to each system consisting of 6, 8 and 10 units, the large and small relations of the MTBF between systems are made clear. 相似文献
30.
Seiji Furusako Yasunobu Miyazaki Hideki Hamatani Yoshiaki Akiniwa 《Welding International》2017,31(8):591-603
In order to achieve lighter and stronger car bodies by applying high strength steel sheets, one of the key technologies is enhancement of joint strength. In this study, we investigated dependence of strength and fracture behaviour on chemical compositions of steels in spot-welded L-type joints in detail. Consequently, the following experimental results were obtained. (1) Maximum load of the joint decreased with increase of carbon (C) and phosphorous (P). The maximum load was decreased by 0.4–0.7 kN with increase of 0.1% in C, with C content ranging from 0.03 to 0.5%, and 0.5 kN with increase of 0.01% in P, with P content ranging from 0 to 0.03%. (2) Fracture portion changed from the outside to the inside of weld metal with increase of C and P. (3) The fracture path was estimated to accord with the solidification segregation site in the weld metal in the case of a steel of 0.2% C, 0.03% P. (4) By implementation of an appropriate post heat during spot welding process for the steel of 0.2% C, 0.03% P, the degree of solidification segregation was clearly reduced and the maximum load of the joints was improved by 70%. 相似文献