来曲唑合成的研究

对抗癌药物来曲唑的合成方法进行了研究,以1-(4-氰基苄基)-1H-1,2,4-三氮唑为原料,分别与对氟苯腈或对氯苯腈在强碱环境中发生亲核取代反应,合成了目标产物,产率分别达到了70%和59%,并测试了产品熔点和红外光谱。以与对氟苯腈相比,对氯苯腈便宜易得,因此以1-(4-氰基苄基)-1H-1,2,4-三氮唑与对氯苯腈制备来曲唑的路线有工业化生产的价值。     

Alkaline treatment kinetics of calcium phosphate by piezoelectric quartz crystal impedance

Calcium phosphate film was prepared by electrochemical deposition technology. Subsequently, the alkaline treatment process of calcium phosphate film in 0.1 mol/L NaOH solution was monitored on real time by the piezoelectric quartz crystal impedance (PQCI) technique. The variations of morphology and composition for the alkaline treatment products were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) and X-ray diffraction (XRD), respectively. The dynamic variations of calcium phosphate can be characterized by the change of equivalent circuit parameters. The results show that the forming process of hydroxyapatite (HA) is composed of three stages: (1) acidic calcium phosphate dissolution; (2) phase transformation; and (3) HA formation. Furthermore, the correlative kinetic equations and parameters are obtained by fitting the static capacitance (C _s)—time curves. Foundation item: Project(2005CB623901) supported by the Major State Basic Research and Development Program of China     

微波辐射磷钼酸铈盐催化柴油氧化脱硫研究

研究微波辐射下磷钼酸铈盐催化模型油和直馏柴油的氧化脱硫反应,考察不同萃取条件对柴油的脱硫率和收率的影响。结果表明,相同反应条件下,相对于普通加热,微波辐射加热时二苯并噻吩（DBT）、苯并噻吩（BT）的脱除率分别提高了4.2倍和3.8倍;在70℃和400 W微波功率下加热2 h,DBT、BT的脱除率分别为95.6%和74.8%;对m（催化剂）/m（柴油）为7.1 mg/g、H2O2初始浓度为0.44 mol/L的柴油,经70℃和4 0 0 W微波功率加热2 h,再在V（萃取剂）/V（柴油）为1/4的条件下用DMF萃取1次,柴油脱硫率为69.6%,收率为97.5%;萃取次数增加,柴油脱硫率提高,但收率明显下降。     

新型液相生物芯片并行检测系统研究

提出基于CCD的高通量高灵敏度的液相生物芯片新型分析系统,采用宽微流通道设计形成平稳、均匀的宽维微流场;荧光同步成像,对传统的基于流式细胞仪的串行分析方法进行了改进,提高了分析速度。     

基于DSP的WAP实时图像浏览平台的研究

针对通用计算机实时图像处理系统的实时性差和性价比低等特点,采用DSP图像处理芯片为核心处理器,研究设计了基于DSP的WAP实时图像浏览平台,实现图像数据采集、编码处理、网络传输等一系列功能.结果表明,该平台处理速度快,图像显示效果良好,能实现支持任一WAP移动终端的实时图像浏览业务,具有广泛的应用前景.     

透水管桩的群桩沉桩室内模型试验研究

本文基于室内模型试验,通过透水管桩和普通管桩沉桩模型试验对比,探究群桩情况下,透水管桩加速桩周土超静孔隙水压力消散的效果和规律。通过试验表明透水管桩更有利于桩周土超静孔压消散,其促进作用沿深度方向递增,沿水平方向递减。透水管桩阻碍了沉桩完成后桩周土超静孔隙水压力的上升,从超静孔隙水压力产生的角度出发,降低了桩周土超静孔隙水压力的峰值,控制了整个桩周土超静孔隙水压力的水平,有利于超静孔隙水压力后期的消散。表明沉桩施工中,透水管桩提高了施工进度,降低了对周围环境的影响。     

谈中国古代体育思想的传承与创新

中国古代体育思想与中国传统丈化思想密不可分,古代体育运动的目的及其衡童的标准、规范都深深地打上儒、道文化思想的络印,形成了"以德为先"、"尚中贵和","天人合一"等为核心的一个符合传统道德规范的体育思想体系,它对我国体育文化的发展产生深远影响.     

Impacts of land-use change on ecosystem service value in Changsha, China

Changsha, a typical city in central China, was selected as the study area to assess the variations of ecosystem service value on the basis of land-use change. The analysis not only included the whole city but also the urban district where the landscape changed more rapidly in the center of the city. Two LANDSAT TM data sets in 1986 and 2000 and land use data of five urban districts from 1995 to 2005 were used to estimate the changes in the size of six land use categories. Meanwhile, previously published value coefficients were used to detect the changes in the value of ecosystem services delivered by each land category. The result shows that the total value of ecosystem services in Changsha declines from 1 009.28 million per year in 1986 to1 009.28 million per year in 1986 to 938.11 million per year in 2000. This decline is largely attributable to the increase of construction land, and the conversion from woodland and water body to cropland to keep the crop production. In the five districts, there is $6.19 million decline in ecosystem service value between 1995 and 2005. Yuelu District has the highest unit ecosystem service value while Yuhua District has the lowest one. This may be attributed to the greater conversion from cropland and grassland to woodland and water body with the increase of construction land in Yuelu District. It is suggested that the increase rate of construction land should be controlled rigorously and the area of woodland and water body should be increased or at least retained in the study area.     

Multichannel noncoherent integration detection using high range resolution profile

A multichannel noncoherent integration detection method based on high range resolution profile was presented in this paper.According to the property of the moment-generating function,the distribution characteristics of the noncoherent integrated signals with or without target presence were derived under the circumstance with noncorrelated Gaussian distribution noises.The loss of noncoherent integration was due to improper selection of integration range of cell numbers.A multichannel noncoherent integration detection scheme where the integration number in each channel varies was proposed to solve this problem.The quality of this method for detection of various targets was evaluated.A comparison of fixed integration range cell number detection and multichannel integration detection for a high range resolution profile was presented.Simulation results indicated that the principle of the method was correct and performed well for unknown physical dimension targets.The method required little prior knowledge about target and was convenient for practical implementation.     

欠驱动水面船舶的曲线航迹跟踪控制

针对欠驱动水面船舶的航迹跟踪控制面临着本质非线性、强耦合和无法线性化处理的控制等问题,首先通过对欠驱动水面船舶航迹控制系统的非线性模型.进行全局微分同胚和反馈变换,构造了由2个级联的子系统构成的航迹跟踪误差系统,然后基于反步法的设计原理,运用Lyapunov直接方法对变换后的误差系统设计了航迹跟踪控制律,该控制律可以实...