Biological characteristics of [~(18)F]-THK523 for tau imaging

Reliable and non-invasive diagnostic tools are highly valuable for successful therapeutic strategies for the treatment of Alzheimer's disease(AD). The existence of neurofibrillary tangles(NFTs) consisting of tau protein are one kind of the pathological features of AD, and its level of severity is correlated with the stage of AD.However, no clinically approved positron emission tomography(PET) probe is currently available for selective imaging of neurofibrillary tangles on patients. In this paper, we report our studies on biological characteristics of [18F]-THK523 as a novel tau imaging probe. With low molecular weight, [18F]-THK523 is stable, electrically neutral, lipophilic and non-mass concentration-dependent. Preliminary biological studies have shown the excellent properties of [18F]-THK523 as brain imaging tracer for further research.     

上海外高桥电厂二期工程锅炉基础混凝土配合比的试配及确定

简要地介绍了外高桥电厂二期工程锅炉基础的工程情况及工程所需混凝土的技术要求和材料选择条件 ;通过多种配合比的试配和对试验结果的分析比较 ,找出了符合本程实际需要的最佳配合比。经工程实用表明 ,利用“双掺”技术 ,能有效地改善和提高混凝土的各项性能 ,取得较好的技术、经济效果。     

木质素阳离子表面活性剂的合成及应用

利用造纸废液中的木质素,合成木质素阳离子表面活性剂;研究合成工艺和作为表面活性剂的有关性能;探讨在水处理絮凝、沥青乳化等方面的应用。     

在铂催化剂上-氧化碳氧化反应的多定态特性

对铂催化剂上一氧化碳氧化反应的多定态特性进行了实验研究,借助于奇异理论和突变理论,对实验结果进行了分析,找出了系统可能存在的定态数目,并预测出在定态数目不同的操作参数区域内,描述系统状态变量与操作参数的分岔图型式,最后,尝试利用系统的多定态特性识别反应的动力学模型,取得了满意的效果.     

介孔材料在基因工程中的应用

综述了介孔材料在基因工程方面的应用研究新进展，详述了近年来国外有关介孔分子筛材料在生物传感器、药物释放和输送、固定蛋白质酶等基因工程领域的研究情况，着重介绍了介孔分子筛在固定蛋白质酶方面的应用前景，展望了国内介孔分子筛在基因工程中的应用。     

液化石油气芳构化过程总包反应热的估算(英文)

The reaction heat effect analysis for the aromatization process of Liquefied Petroleum Gas (LPG) was completed in this paper. In order to characterize this complex reaction system, one set of independent reactions was determined by means of atomic coefficient matrix method. Based on reaction thermodynamic and stoichiometric knowledge, the heat effect, Gibbs free energy change and equilibrium constant for each independent reaction was calculated for the specified conditions. Under these conditions, based on the initial and final composition data from LPG aromatization experiments, the actual extent of reaction for each independent reaction was determined. Furthermore, the global reaction heat and adiabatic temperature rise of LPG aromatization reaction system could be estimated. This work would provide a theoretical guidance for the design and scale-up of reactor for LPG aromatization process, as well as for the selection of proper operating conditions.     

SPG聚丙烯装置反应器的定态模拟

针对中国石油辽河石化分公司的聚丙烯生产装置中测量反应器出口参数的仪表不全的缺陷,通过建立并求解定态数学模型,得到出口浆液浓度、反应物出口浓度等一些重要参数的准确值,并结合实际生产工况,对计算结果进行分析,提出一些优化生产的建议。     

混杂纤维粉煤灰混凝土力学性能和破坏形态试验与分析

为研究混杂纤维、粉煤灰掺量和养护时间对混凝土压拉强度和破坏形态的影响,开展普通混凝土、玄武岩-聚丙烯混杂纤维混凝土、玄武岩-聚丙烯混杂纤维粉煤灰混凝土试样的抗压试验和劈裂抗拉试验,分析了压拉强度和破坏形态,探讨了混杂纤维和粉煤灰的作用机理.研究结果表明:混杂纤维能够提高混凝土的压拉强度,与普通混凝土相比,在养护龄期7d、14d、28d、60d时,其抗压强度和劈裂抗拉强度分别提升了12.72％、8.99％、7.53％、8.01％和11．61％、16.04％、14.75％、10.94％;相同粉煤灰掺量条件下,混凝土的压拉强度随着养护龄期的增加逐渐增大;但相同养护龄期下,混凝土的压拉强度与粉煤灰掺量整体呈负相关,当粉煤灰掺量在10％以内时,混杂纤维粉煤灰混凝土(PBC-FA)的压拉强度增长率整体大于零,且在标准养护28 d时抗压强度满足C30混凝土的要求;混杂纤维能够改善混凝土的破坏形态,提高其塑性变形,而粉煤灰掺量对混杂纤维混凝土(PBC)的塑性基本无影响.