The aim of this prospective study was to evaluate long‐term effects of arteriovenous fistula (AVF) on the development of pulmonary arterial hypertension (PAH) and the relationship between blood flow rate of AVF and pulmonary artery pressure (PAP) in the patients with end‐stage renal disease (ESRD). This prospective study was performed in 20 patients with ESRD. Before an AVF was surgically created for hemodialysis, the patients were evaluated by echocardiography. Then, an AVF was surgically created in all patients. After mean 23.50 ± 2.25 months, the second evaluation was performed by echocardiography. Also, the blood flow rate of AVF was measured at the second echocardiographic evaluation. Pulmonary arterial hypertension was defined as a systolic PAP above 35 mmHg at rest. Mean age of 20 patients with ESRD was 55.05 ± 13.64 years; 11 of 20 patients were males. Pulmonary arterial hypertension was detected in 6 (30%) patients before AVF creation and in 4 (20%) patients after AVF creation. Systolic PAP value was meaningfully lower after AVF creation than before AVF creation (29.95 ± 10.26 mmHg vs. 35.35 ± 7.86 mmHg, respectively, P: 0.047). However, there was no significant difference between 2 time periods in terms of presence of PAH (P>0.05). Pulmonary artery pressure did not correlate with blood flow rate of AVF and duration after AVF creation (P>0.05). In hemodialysis patients, a surgically created AVF has no significant effect on the development of PAH within a long‐term period. Similarly, blood flow rate of AVF also did not affect remarkably systolic PAP within the long‐term period. 相似文献
The aims of the present study were to determine biochemical properties of honey samples and to discriminate pure and adulterated honey produced by the standard bee feeding method (control honey), the shaking method (pure blossom honey), and overfeeding (100 kg/colony syrup) with sucrose syrup (adulterated honey). The biochemical properties evaluated were moisture, ash, acidity, hydroxymethylfurfural (HMF), specific sugars (i.e. fructose, glucose, fructose–glucose, sucrose, and maltose), diastase activity, δ13C value (honey), δ13C value (protein), electrical conductivity, potassium, vitamin C, and proline. Fifteen honey samples were analyzed by discriminant analysis stepwise method. Proline, electrical conductivity and sucrose were found as discriminative characters of samples. Based on these three properties 100% of original group cases (samples) correctly classified in their real group. We found that the honey produced by feeding with 100 kg sucrose syrup per colony contained the sucrose as low as pure blossom honey. Therefore, the sugar (sucrose, fructose and glucose) content of honey cannot be used to distinguish between adulterated (sucrose syrup) and pure blossom honey. 相似文献
We develop a methodology for the analysis of a finite buffer tandem manufacturing system where the machines follow N-policy. We model the system using open queuing networks. The throughput of the system is calculated using decomposition, isolation and expansion methodologies. The methodology is tested rigorously by using orthogonal arrays to design the experiments. A t-test is used to investigate the differences between the results of the methodology and their corresponding simulation results. The comparison shows that the methodology is robust and remarkably accurate over a wide range of parameters. 相似文献
The objective of this study was to identify the high pressure processing conditions (pressure level, time, and temperature) needed to achieve a 5-log reduction of Vibrio parahaemolyticus in live oysters (Crassostrea virginica). Ten strains of V. parahaemolyticus were separately tested for their resistances to high pressure. The two most pressure-resistant strains were then used as a cocktail to represent baro-tolerant environmental strains. To evaluate the effect of temperature on pressure inactivation of V. parahaemolyticus, Vibrio-free oyster meats were inoculated with the cocktail of V. parahaemolyticus and incubated at room temperature (approximately 21 degrees C) for 24 h. Oyster meats were then blended and treated at 250 MPa for 5 min, 300 MPa for 2 min, and 350 MPa for 1 min. Pressure treatments were carried out at -2, 1, 5, 10, 20, 30, 40, and 45 degrees C. Temperatures >/=30 degrees C enhanced pressure inactivation of V. parahaemolyticus. To achieve a 5-log reduction of V. parahaemolyticus in live oysters, pressure treatment needed to be >/=350 MPa for 2 min at temperatures between 1 and 35 degrees C and >/=300 MPa for 2 min at 40 degrees C. 相似文献
The Çeltikçi Coal Basin is a newly discovered coal basin in Central Anatolia where 11 years of open-cut mining has been planned. The bulk of the mining will be conducted below the regional water table; hence, determination of the dewatering requirements and proper design of the dewatering wells plays a critical role. This study (i) defined the dewatering requirements of the open-pit mine, (ii) established a dewatering well design for the area, and (iii) assessed the anticipated impacts of the dewatering activities. For this purpose, a 3-D numerical groundwater flow model was developed using the FEFLOW software. Yearly dewatering requirements were determined under transient conditions. For the dewatering well simulations, two types of dewatering wells were considered: permanent wells located at the open pit boundary that would increase in number as the excavation proceeds and wells located at the periphery of the yearly excavated area that would be operational for about two years. The simulation results indicated that 894 wells were required to satisfy dry working conditions; the average pumping rate throughout the mine life was calculated as 322 L/s. The impacts of open-pit dewatering on groundwater resources were assessed in terms of spring discharge and base flow rates in the nearby Kirmir stream. As a result of dewatering, most of the village water supply springs and fountains will dry up in the area. In addition, the base flow rates to the Kirmir stream will be decreased by 15%.