The temperature mobility degradation influence on the zero temperature coefficient of partially and fully depleted SOI MOSFETs

The zero temperature coefficient (ZTC) is investigated experimentally in partially (PD) and fully depleted (FD) SOI MOSFET fabricated in a 0.13 μm SOI CMOS technology. A simple model to study the behavior of the gate voltage at ZTC (V_ZTC) is proposed in the linear and the saturation region. The influence of the temperature mobility degradation on V_ZTC is analyzed for PD and FD devices. Experimental results show that the temperature mobility degradation is larger in FD than in PD devices, which is responsible for the V_ZTC decrement observed in FD instead of the increment observed in PD devices when the temperature increases. The analysis takes into account temperature dependence model parameters such as threshold voltage and mobility. The analytical predictions are in very close agreement with experimental results in spite of the simplification used for the V_ZTC model as a function of temperature in the linear and the saturation region.     

Beyond self-esteem: Influence of multiple motives on identity construction.

Diverse theories suggest that people are motivated to maintain or enhance feelings of self-esteem, continuity, distinctiveness, belonging, efficacy, and meaning in their identities. Four studies tested the influence of these motives on identity construction, by using a multilevel regression design. Participants perceived as more central those identity elements that provided a greater sense of self-esteem, continuity, distinctiveness, and meaning; this was found for individual, relational, and group levels of identity, among various populations, and by using a prospective design. Motives for belonging and efficacy influenced identity definition indirectly through their direct influences on identity enactment and through their contributions to self-esteem. Participants were happiest about those identity elements that best satisfied motives for self-esteem and efficacy. These findings point to the need for an integrated theory of identity motivation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The role of product feature relations in a knowledge based methodology to manage design modifications for product measurability

During product development, the verification process should already be considered at the design phase to ensure that the characteristics of the product are measured effectively and reliably. Moreover, the verification process may prove more effective if the inspector is aware of the specific designer's intents. The development of the new ISO GPS (Geometrical Product Specifications) standards is mainly founded on these considerations. In accordance with the ISO GPS concepts, previous work developed a knowledge based system named Design GuideLines (DGLs). This system provides the designer with the knowledge concerning the manufacturing and verification procedures/tools and better links the manufacturing and verification processes to the designer's activities/needs. Further research then exploited the DGLs to discover the relations among product features determined by a particular manufacturing process.

This work again uses the DGLs to prove that further relations among product features may also be determined by the verification process. This knowledge helps designers in understanding the consequences of the modifications applied to the product features required to improve the measurability of the product. Moreover, inspectors can better manage the verification procedure knowing these relations among the product features.     

Graph cuts via l1 norm minimization

Graph cuts have become an increasingly important tool for solving a number of energy minimization problems in computer vision and other fields. In this paper, the graph cut problem is reformulated as an unconstrained $\ell_1$ norm minimization which can be solved effectively using interior point methods. This reformulation exposes connections between the graph cuts and other related continuous optimization problems. Eventually the problem is reduced to solving a sequence of sparse linear systems involving the Laplacian of the underlying graph. The proposed procedure exploits the structure of these linear systems in a manner that is easily amenable to parallel implementations. Experimental results obtained by applying the procedure to graphs derived from image processing problems are provided.     

‘Unintended Cities’ and Inoperative Violence. Housing Resistance in Yangon

ABSTRACT

Urban development and city expansion in Yangon, Myanmar happened through the forced resettlement of people from the city toward the periphery. Forced resettlement has become the main mode of urban production since the British colonisation, and is sustained by laws, orders and policies. Building on Benjamin’s and Agamben’s essays on violence, we claim that it is possible to interrupt the endless cycle of law and violence by locating violence outside the debate around ‘means and ends’. Stemming from the authors’ experience and repeated encounters with practices of social mobilisation of women in Yangon over the last five years, we have traced the potential for deactivating the ‘signature’ of violence in the everyday practices of resistance of urban dwellers in the township of HlaingTharYar in Yangon. Through the incremental occupation, trespassing and building up of peripheral ‘vacant’ land, organised women’s groups are challenging the spatial order established by post/colonial regimes.     

Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities

Metal complexes play a crucial role in pharmaceutical sciences owing to their wide and significant activities. Schiff bases (SBs) are multifaceted pharmacophores capable of forming chelating complexes with various metals in different oxidation states. Complexes with SBs are extensively studied for their numerous advantages, including low cost and simple synthetic strategies. They have been reported to possess a variety of biological activities, including antimicrobial, anticancer, antioxidant, antimalarial, analgesic, antiviral, antipyretic, and antidiabetic ones. This review summarizes the most recent studies on the antimicrobial and antiproliferative activities of SBs-metal complexes. Moreover, recent studies regarding mononuclear and binuclear complexes with SBs are described, including antioxidant, antidiabetic, antimalarial, antileishmanial, anti-Alzheimer, and catecholase activities.     

Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration

The H Ferritin subunit (FTH1), as well as regulating the homeostasis of intracellular iron, is involved in complex pathways that might promote or inhibit carcinogenesis. This function may be mediated by its ability to interact with different molecules. To gain insight into the FTH1 interacting molecules, we analyzed its interactome in HEK293T cells. Fifty-one proteins have been identified, and among them, we focused our attention on a member of the peroxiredoxin family (PRDX6), an antioxidant enzyme that plays an important role in cell proliferation and in malignancy development. The FTH1/PRDX6 interaction was further supported by co-immunoprecipitation, in HEK293T and H460 cell lines and by means of computational methods. Next, we demonstrated that FTH1 could inhibit PRDX6-mediated proliferation and migration. Then, the results so far obtained suggested that the interaction between FTH1/PRDX6 in cancer cells might alter cell proliferation and migration, leading to a less invasive phenotype.     

A Hypothalamic Mechanism Regulates the Duration of a Migraine Attack: Insights from Microstructural and Temporal Complexity of Cortical Functional Networks Analysis

The role of the hypothalamus and the limbic system at the onset of a migraine attack has recently received significant interest. We analyzed diffusion tensor imaging (DTI) parameters of the entire hypothalamus and its subregions in 15 patients during a spontaneous migraine attack and in 20 control subjects. We also estimated the non-linear measure resting-state functional MRI BOLD signal’s complexity using Higuchi fractal dimension (FD) and correlated DTI/fMRI findings with patients’ clinical characteristics. In comparison with healthy controls, patients had significantly altered diffusivity metrics within the hypothalamus, mainly in posterior ROIs, and higher FD values in the salience network (SN). We observed a positive correlation of the hypothalamic axial diffusivity with migraine severity and FD of SN. DTI metrics of bilateral anterior hypothalamus positively correlated with the mean attack duration. Our results show plastic structural changes in the hypothalamus related to the attacks severity and the functional connectivity of the SN involved in the multidimensional neurocognitive processing of pain. Plastic changes to the hypothalamus may play a role in modulating the duration of the attack.     

Metabolomic Approaches for Detection and Identification of Biomarkers and Altered Pathways in Bladder Cancer

Metabolomic analysis has proven to be a useful tool in biomarker discovery and the molecular classification of cancers. In order to find new biomarkers, and to better understand its pathological behavior, bladder cancer also has been studied using a metabolomics approach. In this article, we review the literature on metabolomic studies of bladder cancer, focusing on the different available samples (urine, blood, tissue samples) used to perform the studies and their relative findings. Moreover, the multi-omic approach in bladder cancer research has found novel insights into its metabolic behavior, providing excellent start-points for new diagnostic and therapeutic strategies. Metabolomics data analysis can lead to the discovery of a “signature pathway” associated with the progression of bladder cancer; this aspect could be potentially valuable in predictions of clinical outcomes and the introduction of new treatments. However, further studies are needed to give stronger evidence and to make these tools feasible for use in clinical practice.     

A combined experimental–numerical rheometric and mechanical characterization of EPM/EPDM rubber for medium voltage cable applications vulcanized with peroxides

The vulcanization of medium and high voltage (M‐H V) cables is an important industrial application where manufacturers use principally EPM/EPDM, crosslinked polyethylene (XLPE) and now also thermoplastic rubbers. In the present article, an EPDM compound for medium voltage cables—normally distributed to producers in pellets and ready to be cured—is considered and several experimental tests (rheometer curves and mechanical characterizations) are conducted changing controlled curing temperature, peroxide type and peroxide concentration. In particular, tests are replicated in a temperature range between 160 and 200°C, with data provided every 20°C, using two different peroxides, a mixture of three commercial peroxides at five different concentrations. A huge amount of experimental data (cure curves) is obtained (one for each temperature, peroxide used and concentration) and results are critically compared one each other, to have a quantitative insight into the most effective temperature and peroxide to be used during this kind of vulcanization, with the aim of maximizing vulcanization velocity, final torque reached and mechanical properties of cured rubber. The comprehensive experimental study proposed is finally assessed from a numerical point of view, utilizing a complex kinetic scheme constituted by reactions occurring in series and parallel, which allows estimating numerically the vulcanization degree by means of a single second order nonlinear differential equation, with unknown parameters determined through non‐linear least squares fitting, with target data represented by experimental rheoemeter curves. The experimental fitting is almost perfect for all the cases analyzed and is aimed at predicting (without an expensive experimentation) the most suitable production parameters (e.g., curing time and temperature) to guarantee improved mechanical properties and a good aging resistance of the items. In addition, the numerical approach could allow finding the most suitable recipe, also in presence of mixtures of peroxides, able to provide items with a uniform vulcanization level. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 40075.