A methodology for fabrication of thermomechanically activated switchable surface wettability

In this study a platform is laid out for the creation of a multitiered surface exhibiting switchable wettability. This is done through a combination of both an acrylate‐based polymer understructure photopolymerized into a pillared array, and selectively placed surface treatments on these pillars. The acrylate‐based polymer is created through a systematic study and is shown to exhibit drastic alterations in material stiffness over a 19 °C temperature transition under aqueous conditions, allowing for stiff, erect pillars in the low temperature state, and pliable pillars that can easily be bent in the high temperature state. The glass transition temperature and onset temperature for the polymer system is found to be 49 and 30 °C, respectively. Three different surface treatments, including trichloro(1H,1H,2H,2H‐perfluorooctyl)silane, polydimethylsiloxane, and polydopamine, are investigated using static contact angle studies, and are selectively deposited onto the pillared surface such that a hydrophobic surface is exposed with the pillars erect, and a hydrophilic surface is exposed with the pillars in the bent state. The surface is shown to transition between first a hydrophobic, then hydrophilic state and return to a hydrophobic state when the investigations are coupled together forming a hierarchical surface structure. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 44122.     

Immunoproteasome β5i‐Selective Dipeptidomimetic Inhibitors

N,C‐capped dipeptides belong to a class of noncovalent proteasome inhibitors. Herein we report that the insertion of a β‐amino acid into N,C‐capped dipeptides markedly decreases their inhibitory potency against human constitutive proteasome β5c, while maintaining potent inhibitory activity against human immunoproteasome β5i, thereby achieving thousands‐fold selectivity for β5i over β5c. Structure–activity relationship studies revealed that β5c does not tolerate the β‐amino acid based dipeptidomimetics as does β5i. In vitro, one such compound was found to inhibit human T cell proliferation. Compounds of this class may have potential as therapeutics for autoimmune and inflammatory diseases with less mechanism‐based cytotoxicity than agents that also inhibit the constitutive proteasome.     

Multilevel surrogate modeling of an amine scrubbing process for CO2capture

Surrogate models provide a powerful method for simplifying calculations within complex simulations. While surrogate models are broadly applied within chemical engineering, little research exists investigating the level of surrogacy's impact on a simplified process model. In this work, artificial neural networks (ANN) and Kriging models are used as surrogate models at the process, process unit, and thermodynamic levels for a CO₂ amine scrubbing process. The surrogated models are evaluated against an Aspen Plus simulation for accuracy, convergence behavior, computational cost, and ability to extrapolate. The thermodynamic and process unit models can better handle discontinuous, non-smooth behavior, and convergence issues in the surrogated truth model, but poor conditioning in the final system of equations results in a lower accuracy and convergence rate than the process level surrogate. Beyond model accuracy, availability of diverse data, intended re-usability, and the desired outputs must be considered when selecting a level of abstraction.     

A canonical structure for constrained optimal control problems

We consider a general class of optimal control problems with regional pole and controller structure constraints. Our goal is to show that for a fairly general class of regional pole and controller structure constraints, such constrained optimal control problems can be transformed to a new one with a canonical structure. A three-step transformation procedure is used to achieve our goal, which essentially amounts to repeated augmentations of plant dynamics and repeated reductions of the controller. The transformed problem is one of the standard optimal static output feedback with a decentralized and repeated structure.     

Field Performance of High Oleic Soybeans with Mutant FAD2-1A and FAD2-1B Genes in Tennessee

Soybean [Glycine max (L.) Merr.] oil with high oleic acid (>75%) has increased oxidative stability and health benefits that are valuable for food, fuel, and industrial products. It has been determined that two naturally occurring mutations in genes FAD2-1A and FAD2-1B can combine to produce high oleic soybeans. The objective of this study was to test the effect of these mutant alleles on seed yield and oil and protein concentration. Molecular markers assisted in the creation of a population of 48 BC₃F_2:4 lines (93.75% expected genome commonality). Each line was classified into one of four genotypic groups where both FAD2-1A and FAD2-1B genes were either homozygous wild type or mutant, respectively. Twelve lines for each genotypic group were evaluated in three replications at six locations across Tennessee. There was no seed yield difference between the high oleic genotypic group and the other groups (P < 0.05). On the other hand, there were differences in fatty acid profiles and oil and protein concentrations. In combination, the mutant FAD2-1A and FAD2-1B alleles produced a mean of 803.1 g kg⁻¹ oleic acid. This is, on average, approximately 500 g kg⁻¹ more oleic acid compared to soybean lines with only one mutant FAD2-1 allele. The high oleic double mutant group had more total oil (228.0 g kg⁻¹) and protein (401.0 g kg⁻¹) compared to all other genotypic groups (P < 0.05). Overall, this specific combination of mutant FAD2-1A and FAD2-1B alleles appears to generate conventional high oleic soybeans without a yield drag.     

Hydrodesulfurization of Diesel Feeds by Association of a Catalytic Process and a Separation Process Using Charge-Transfer Complexes

While deep hydrodesulfurization of gas oil is more and more important, elimination of sulfur compounds such as 4,6-dialkyldibenzothio-phenes still attracts considerable attention. A new process based on the association of a separation process by charge-transfer complex (CTC) formation and classical catalytic hydrotreating (HDT) was evaluated. The results indicated that a CTC pretreatment allows the rate of hydrodesulfurization (HDS) to increase and the final sulfur level to decrease. This process is even more efficient for feeds difficult to desulfurize.     

Molecular weight distribution of polyphenylene sulfide by high temperature gel permeation chromatography

Poly(phenylene sulfide) (PPS) has been characterized using a novel high temperature gel permeation chromatograph (GPC). Samples were injected in slurry form at ambient temperature, and redissolved by an in-line precolumn heater at 250°C. A viscometer consisting of a capillary tube with inlet and outlet taps connected to a sensitive differential pressure transducer was used as sole detector, with deflections converted to concentration using the column calibration. Columns and viscometer were operated at 210°C. Universal calibration was carried out using intrinsic viscosity/molecular weight relations for polystyrene and PPS, determined by light scattering. Satisfactory operation was confirmed by agreement between intrinsic viscosity calculated from GPC with independently measured values, and comparisons with melt flow data. Samples of PPS tested were found to be of relatively narrow distribution, with M_w/M_n typically less than two.