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41.
42.
Quantitative RT-PCR for measuring gene expression   总被引:1,自引:0,他引:1  
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43.
We establish a one-to-one correspondence between information inequalities and group inequalities. The major implication of our result is that we can prove information inequalities by proving the corresponding group inequalities, and vice versa. By giving a group-theoretic proof for all Shannon-type inequalities, we suggest that new inequalities could be discovered by making use of the rich set of tools in group theory. On the other hand, via a non-Shannon-type information inequality discovered by Zhang and Yeung (1997), we obtain a new inequality in group theory whose meaning is yet to be understood  相似文献   
44.
This paper presents a novel and generic PC/PLC-based software/hardware architecture for the control of flexible manufacturing workcells. The proposed implementation methodology is based on the utilization of any one of the available formal discrete-event-system control theories in conjunction with state-of-the-art industrial programmable-logic controllers (PLCs). The methodology has been illustrated to be a viable technique through its actual implementation in our laboratory using a robotic-workcell testbed. The specific control theory used is a combination of Extended Moore Automata and Ramadge-Wonham Automata that has been developed by our research group. The modular control software architecture has been developed for MS-Windows environments (running on one PC interfaced to the PLCs) and allows the use of different formal control theories as well as different commercial PLC hardware. The effective graphical user interface provides a transparent programming environment, where users are not expected to have a full knowledge of the formal control theory used.  相似文献   
45.
BACKGROUND: It has been suggested that excessive formation of nitric oxide (NO) is responsible for the hyperdynamic circulation observed in portal hypertension. Substance P is a neuropeptide partly cleared by the liver and causes vasodilatation through the activation of the endothelial NO pathway. However, there are no previously published data concerning the plasma level of substance P in cirrhotic rats and its relationship to NO. METHODS: Plasma concentrations of substance P and nitrate/nitrite (an index of NO production) were determined in control rats and cirrhotic rats with or without ascites using an enzyme-linked immununosorbent assay and a colorimetric assay, respectively. In addition, systemic and portal hemodynamics were evaluated by a thermodilution technique and catheterization. RESULTS: Cirrhotic rats with and without ascites had a lower systemic vascular resistance (2.6 +/- 0.2 and 3.9 +/- 0.4 mmHg ml(-1) x min x 100 g body weight, respectively) and higher portal pressure (14.6 +/- 0.6 and 11.3 +/- 1.8 mmHg) than control rats (6.5 +/- 0.3 mmHg x ml(-1) x min x 100 g BW and 6.8 +/- 0.2 mmHg, respectively, P < 0.05), and cirrhotic rats with ascites had the lowest systemic vascular resistance. Plasma levels of nitrate/nitrite progressively increased in relation to the severity of liver dysfunction (control rats, 2.7 +/- 0.5 nmol/ml; cirrhotic rats without ascites, 5.6 +/- 1.3 nmol/ml; cirrhotic rats with ascites, 8.3 +/- 2.2 nmol/ml; P < 0.05). Cirrhotic rats with ascites displayed higher plasma values of substance P (57.7 +/- 5.9 pg/ml) than cirrhotic rats without ascites (37.9 +/- 3.1 pg/ml, P < 0.05) and control rats (30.1 +/- 1.0 pg/ml, P < 0.05). There was no significant difference in plasma substance P values between control rats and cirrhotic rats without ascites (P > 0.05). No correlation was found between plasma levels of substance P and nitrate/nitrite (r = 0.318, P > 0.05). CONCLUSIONS: Excessive formation of NO may be responsible, at least partly, for the hemodynamic derangements in cirrhosis. Although substance P may not participate in the initiation of a hyperdynamic circulation in cirrhosis, it may contribute to the maintenance of the hyperdynamic circulation observed in cirrhotic rats with ascites.  相似文献   
46.
Focal and segmental glomerulosclerosis (FSG) with endothelial tubuloreticular inclusions (TRIs) is the typical lesion of human HIV-associated glomerulopathy. Autopsy studies showed the presence of FSG in 3 of 15 macaques dying 15-120 weeks after experimental infection with a simian immunodeficiency virus (SIVMne). Ultrastructural studies generally revealed numerous endothelial TRIs (also present in normals), mesangial expansion, and evidence of mesangial cell injury. One additional animal had a small-vessel polyarteritis with a proliferative and focally crescentic glomerulonephritis; seven animals had mild, multifocal interstitial nephritis. All animals had documented viremia after infection; 14 of 15 developed antibodies to SIV postinoculation. Additional postmortem findings included severe enterocolitis, encephalitis, and opportunistic infections. In contrast, autopsy studies of macaques infected with a type D simian retrovirus (SAIDS-D/Washington, SRV-2) for similar periods of time (n = 40) showed no evidence of FSG. One SRV-infected animal had a mild proliferative glomerulonephritis. These studies indicate SIV-infected primates may provide a relevant model for study of human HIV-associated nephropathy. They also indicate the variable pathology that can be seen in primate infections of distinct retrovirus types, each of which produces a simian immunodeficiency state that resembles human AIDS.  相似文献   
47.
介绍碾压混凝土坝发展的历程,简述了碾压混凝土筑坝技术以及施工工艺、特点、程序、质量控制等相关方面的施工经验。  相似文献   
48.
AIN with high thermal conductivity was fabricated by pressureless sintering with Y2O3 as the sintering aid. The thermal conductivity was observed to increase with sintering time (up to 8 h) at 1810 °C. The distribution of the sintering aid was identified as one of the major factors influencing the thermal conductivity in AIN. Non-uniform distribution of the grain boundary phase was found to be associated with a significant amount of porosity, resulting in the enhancement of phonon scattering and thereby lowering the thermal conductivity.  相似文献   
49.
Based on the concepts of cascade multilevel converters and one-cycle technique, comparisons are conducted to characterize the distortion of the pulsewidth modulation (PWM) and one-cycle control methods that were applied to converters. Simulation results for the different control schemes are obtained in PSIM software initially to see the effect of one-cycle control different from that of PWM control. Through the comparisons, the advantages and disadvantages are identified for each method. The one-cycle scheme is better than PWM control in reducing undesirable harmonics and tracing dynamic waveforms. Simulation and experimental results are also provided to verify the conclusions.  相似文献   
50.
 In this paper, filters with rectangular fibres arranged in a staggered and parallel array and placed transverse to the flow are studied numerically. A two- dimensional flow field is obtained by solving Navier–Stokes equations with the control volume method. Periodic boundary conditions are introduced in the calculation. In order to achieve higher accuracy, a second-order upwind scheme is adopted and a fine mesh is arranged near the fibre and the symmetrical plane of the flow field where large gradients in velocity are expected. Particle trajectories are calculated by solving the corresponding Lagrangian equation of motion to obtain the collection efficiency of a single rectangular fibre, in which positions of the approaching particles on the inlet plane of the flow field are randomly distributed according to the Monte-Carlo principle. The simulation considers all the important mechanisms of particle capture including interception, inertial impaction and Brownian motion. Effects of fibre aspect ratio, filter packing density, particulate size and Reynolds number on the collection efficiency are numerically determined. The volumetric packing density ranges from 0.4 to 4% and the particle diameter is from 0.01 μm to 2 μm. Reynolds number based on the height of computational domain varies from 20 to 100 and the aspect ratio is from 0.1 to 10. Simulations with and without Brownian motion are carried out for different Reynolds numbers, packing densities and aspect ratios and the results show that Brownian effects are significant for particles smaller than 1 μm. Received 25 May 2001  相似文献   
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