Superconductive properties of vanadium and their impurity dependence

We report on a comprehensive study of the magnetic properties of the super-conductor vanadium. Starting from a high-purity sample (RRR=1900), we use magnetization measurements to evaluate the primary superconductive parameters of vanadium and their impurity dependence up to 3.1. For the clean limit we findT _c0 =5.47 K and ₀ =0.78. From the impurity dependence of the transition temperature an rms gap anisotropy of 16% is obtained. Furthermore, for Ginzburg-Landau parameters 1.5 an attractive flux line interaction is found. The experiments on H_c2 anisotropy show results comparable to those for niobium, i.e., a slow decrease of the anisotropy coefficient a₄ with increasing impurity parameter and a much faster decrease of the 1=6 component. A detailed analysis of these results awaits further progress of theory.This work was supported in part by Fonds zur Förderung der Wissenschaftlichen Forschung, Wien, under contract No. 3973.     

Inhibition of HeLa cell messenger RNA translation by 7-methylguanosine 5'-monophosphate

Translation of HeLa cell RNA containing poly(A) in a wheat germ cell-free system is markedly but incompletely inhibited by 7-methylguanosine 5'-monophosphate (m7G5'p). We have analyzed the translation products synthesized in the presence of different concentrations of m7G5'p and find that translation of all mRNAs is equally inhibited. To demonstrate the specificity of the inhibitor for RNAs with 5'-terminal m7G5' ppp... we show that specific translation products of satellite tobacco necrosis virus RNA, which does not have this 5' terminus, are synthesized in the presence of m7G5' p. Protein synthesis programmed by endogenous mRNA in a HeLa cell-free system is inhibited after a 10-min lag by m7G5' p. Other guanosine nucleotides without the 7-methyl group or with the phosphate in a different position are not inhibitor. We show that translation of all mRNAs is inhibited to a similar extent by m7G5'p in the HeLa cell-free system, by synthesizing 35S-labeled proteins in the presence of different inhibitory concentrations of this nucleotide and analyzing the translation products by electrophoresis and autoradiography. Translation of encephalomyocarditis virus RNA added to the HeLa cell-free system is not inhibited by m7"g5p; this viral RNA does not have this nucleotide at the 5' terminus. This indicates that m7G5'p specifically inhibits translation of mRNAs with the 5' terminus m7G5'ppp... and suggests that initiation of translation of picornavirus RNA may proceed via a mechanism different from that of cellular mRNAs.     

Complex system reliability modelling with Dynamic Object Oriented Bayesian Networks (DOOBN)

Nowadays, the complex manufacturing processes have to be dynamically modelled and controlled to optimise the diagnosis and the maintenance policies. This article presents a methodology that will help developing Dynamic Object Oriented Bayesian Networks (DOOBNs) to formalise such complex dynamic models. The goal is to have a general reliability evaluation of a manufacturing process, from its implementation to its operating phase. The added value of this formalisation methodology consists in using the a priori knowledge of both the system's functioning and malfunctioning. Networks are built on principles of adaptability and integrate uncertainties on the relationships between causes and effects. Thus, the purpose is to evaluate, in terms of reliability, the impact of several decisions on the maintenance of the system. This methodology has been tested, in an industrial context, to model the reliability of a water (immersion) heater system.     

Elemental dissolution study of Pu-bearing borosilicate glasses

Single-pass flow-through tests were conducted to study the effects of self-radiation damage from alpha decay on dissolution kinetics of three radiation-aged Pu-bearing (1 mass% PuO₂) borosilicate glasses over a pH interval of 9–12 at 80–88 °C. The chemical compositions of the glasses were identical except the ²³⁹Pu/²³⁸Pu isotopic ratio, which was varied to yield accumulated doses of 1.3 × 10¹⁶, 2.9 × 10¹⁷ and 2.6 × 10¹⁸ -decays/g at the time of testing. Release of Al, B, Cs, Na, Si and U to solution increased with increasing pH, whereas Ca, Pu and Sr were invariant over the pH interval. Average dissolution rates, based on B release, were identical within experimental uncertainty for all three glass compositions and increased from 0.17 ± 0.07 at pH(23 °C) 9 to 10.6 ± 2.7 (g/(m² d¹)) at pH(23 °C) 12. Release rates of Pu were 10²- to 10⁵-fold slower compared to all other elements and were not affected by isotopic composition, self-radiation damage sustained by the glass, or pH. These data demonstrate that self-radiation damage does not affect glass dissolution rates, despite exposure to internal radiation doses for >20 years.     

Investigation of 3D crack propagation problems via fast BEM formulations

Abstact The simulation of 3D fatigue crack growth is investigated and in combination with suitable experiments it is aimed to identify a reliable crack growth criterion. To perform the crack growth simulation as effectively as possible the boundary element method (BEM) in terms of the 3D Dual BEM is utilized. The relevant boundary integral equations are evaluated in the framework of a collocation procedure. To compress the system matrix and to speed-up the solution procedure the adaptive cross approximation (ACA) method is applied. It is an algebraic technique acting purely on the system matrix itself. The efficiency of this procedure with respect to crack problems will be shown on both a standard fracture specimen and an industrial application.     

Adoption of electronic options trading at the ISE

US brokerage firms have shown strong interest in a new alternative for trading of equity options since the 26 May 2000 launch of the International Securities Exchange (ISE), an all-electronic trading platform. Although the collective impact of these adoption decisions led to a successful launch and a formidable competitor to the four established options markets in the US, major brokerage firms differ widely in their usage and adoption rates.     

Das Problem der verantworteten Therapieentscheidung in der Neonatologie

Definition of the problem: Physicians and nurses who work in neonatology—as in intensive care at all—are often forced to decide whether to stop or to continue with the treatment of a severely ill patient. The literature provides several decision making instruments, which are meant to help and to rationalize such decisions. Method and conclusion: Two of these instruments (“Schema zur ethischen Urteilsbildung nach dem Muster der aristotelischen Ethik”, Honnefelder 1994; “Nimwegener Methode für ethische Fallbesprechung”, Gordijn 1998) were tested by retrospectively examining two cases of our NICU. Results of our study show that the use of a decision making instrument is basically helpful. But the above mentioned instruments showed also shortcomings when used in the framework of neonatology. Therefore we developed the “Kölner Arbeitsbogen zur ethischen Entscheidungsfindung in der Neonatologie”, which is adapted to the specific needs of neonatology.     

Opposing Effects of D? and D? Receptor Activation on Odor Discrimination Learning.

Dopaminergic modulation of cortical activity has been implicated in the formation of reward associations. There is abundant evidence for dopaminergic effects on olfactory processing. Using an olfactory discrimination task, the authors show that D? and D? dopamine receptors can regulate rats' olfactory discrimination capacities and that the effects of receptor activation functionally oppose one another. Injection of either the D? agonist SKF 38393 (10 mg/kg) or the D? antagonist spiperone (0.62 mg/kg) facilitated the discrimination of similar odorants but had no effect on the discrimination of dissimilar odorants, whereas both the D, antagonist SCH 23390 (0.025 mg/kg) and the D? agonist quinpirole (0.2 mg/kg) significantly impaired rats' ability to discriminate similar and dissimilar odorants. (PsycINFO Database Record (c) 2010 APA, all rights reserved)