全文获取类型
收费全文 | 1020篇 |
免费 | 29篇 |
专业分类
电工技术 | 27篇 |
综合类 | 1篇 |
化学工业 | 262篇 |
金属工艺 | 14篇 |
机械仪表 | 23篇 |
建筑科学 | 60篇 |
矿业工程 | 1篇 |
能源动力 | 23篇 |
轻工业 | 153篇 |
水利工程 | 1篇 |
石油天然气 | 3篇 |
无线电 | 65篇 |
一般工业技术 | 168篇 |
冶金工业 | 94篇 |
原子能技术 | 6篇 |
自动化技术 | 148篇 |
出版年
2023年 | 4篇 |
2022年 | 16篇 |
2021年 | 22篇 |
2020年 | 9篇 |
2019年 | 11篇 |
2018年 | 20篇 |
2017年 | 28篇 |
2016年 | 19篇 |
2015年 | 16篇 |
2014年 | 16篇 |
2013年 | 24篇 |
2012年 | 37篇 |
2011年 | 64篇 |
2010年 | 51篇 |
2009年 | 46篇 |
2008年 | 55篇 |
2007年 | 64篇 |
2006年 | 33篇 |
2005年 | 45篇 |
2004年 | 28篇 |
2003年 | 30篇 |
2002年 | 24篇 |
2001年 | 20篇 |
2000年 | 30篇 |
1999年 | 18篇 |
1998年 | 41篇 |
1997年 | 24篇 |
1996年 | 18篇 |
1995年 | 28篇 |
1994年 | 22篇 |
1993年 | 14篇 |
1992年 | 15篇 |
1991年 | 6篇 |
1990年 | 12篇 |
1989年 | 14篇 |
1988年 | 10篇 |
1987年 | 6篇 |
1986年 | 4篇 |
1985年 | 6篇 |
1984年 | 8篇 |
1983年 | 10篇 |
1982年 | 8篇 |
1981年 | 4篇 |
1980年 | 10篇 |
1978年 | 5篇 |
1976年 | 8篇 |
1974年 | 4篇 |
1973年 | 4篇 |
1925年 | 4篇 |
1904年 | 3篇 |
排序方式: 共有1049条查询结果,搜索用时 0 毫秒
41.
Claas Spille Anastasios Lyberis Maria Isabelle Maiwald Dirk Herzog Marko Hoffmann Claus Emmelmann Michael Schlüter 《化学工程与技术》2020,43(10):2053-2061
In chemical process engineering, fast gas-liquid reactions often suffer from an inefficient distribution of gas and therefore mixing and mass transfer performance. This study deals with the possibility of influencing the local gas holdup and bubble size distribution in a gas-liquid process using additively manufactured lattice structures (AMLS). The used measuring technique to study bubble size, velocity, and the local gas holdup is a photo-optical needle probe. By using AMLS, a significant radial homogenization of the local gas holdup and the mean bubble size is achieved. Furthermore, it can be demonstrated that the bubble size can be tailored by the geometry of the inserted structure. It is illustrated that the mean bubble velocities are lowered within the lattice resulting in a higher residence time of the dispersed phase with an impact on the mass transfer performance within the AMLS. 相似文献
42.
Anja Wessely Theresa Steeb Ulrike Leiter Claus Garbe Carola Berking Markus Vincent Heppt 《International journal of molecular sciences》2020,21(23)
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer that predominantly arises in chronically sun-damaged skin. Immunosuppression, genetic disorders such as xeroderma pigmentosum (XP), exposure to certain drugs and environmental noxae have been identified as major risk factors. Surgical removal of cSCC is the therapy of choice and mostly curative in early stages. However, a minority of patients develop locally advanced tumors or distant metastases that are still challenging to treat. Immune checkpoint blockade (ICB) targeting CTLA-4, PD-L1 and PD-1 has tremendously changed the field of oncological therapy and especially the treatment of skin cancers as tumors with a high mutational burden. In this review, we focus on the differences between cSCC and cutaneous melanoma (CM) and their implications on therapy, summarize the current evidence on ICB for the treatment of advanced cSCC and discuss the chances and pitfalls of this therapy option for this cancer entity. Furthermore, we focus on special subgroups of interest such as organ transplant recipients, patients with hematologic malignancies, XP and field cancerization. 相似文献
43.
Metabolic profile biomarkers of metal contamination in a sentinel terrestrial species are applicable across multiple sites 总被引:3,自引:0,他引:3
Bundy JG Keun HC Sidhu JK Spurgeon DJ Svendsen C Kille P Morgan AJ 《Environmental science & technology》2007,41(12):4458-4464
In this study, we addressed the question of whether an omic approach could genuinely be useful for biomarker profile analysis across different field sites with different physicochemical characteristics. We collected earthworms (Lumbricus rubellus) from seven sites with very different levels of metal contamination and prevailing soil type and analyzed tissue extracts by 1H nuclear magnetic resonance spectroscopy. Pattern recognition analysis of the data showed that both site- and contaminant-specific effects on the metabolic profiles could be discerned. Zinc was identified as the probable major contaminant causing a metabolic change in the earthworms. Individual sites could be resolved on the basis of NMR spectral profiles by principal component analysis; these site differences may also have been caused by additional abiotic factors such as soil pH. Despite an inevitable degree of confounding between site and contaminant concentrations, it was possible to identify metabolites which were correlated with zinc across all different sites. This study therefore acts as a proof of principle for the use of NMR-based metabolic profiling as a diagnostic tool for ecotoxicological research in polluted field soils. 相似文献
44.
Hanne Boskov Hansen Claus V Rasmussen Knud Erik Bach Knudsen se Hansen 《Journal of the science of food and agriculture》2003,83(1):76-85
The aim of this study was to measure the variation in dietary fibre (DF) content and composition among different rye varieties grown in the same location in three successive years and to estimate the contributions of genotype and harvest year to this variation. The study included grain from 19 different varieties of rye, of which seven varieties were analysed in all three years. The content of total DF in all samples ranged from 147 to 209 g kg?1 dry matter (dm), with 34–66 g kg?1 being water‐extractable (WE) DF and 108–159 g kg?1 being water‐unextractable (WUE) DF. The main DF component was arabinoxylan (AX) with a content of 80–121 g kg?1 dm, of which 26–41 g kg?1 dm was WE AX. The ratio of arabinose to xylose (ara/xyl) of total AX ranged from 0.59 to 0.69. The content of β‐glucan was 13–22 g kg?1 dm and that of fructan was 45–64 g kg?1 dm. Analysis of the data from seven varieties and three harvest years showed a highly significant influence of harvest year on most DF components. Significant genotype effects were found for the contents of total DF, total AX, β‐glucan and fructan and for the ara/xyl ratio of total and WUE AX. Estimation of variance components showed that yearly variations in the contents of total DF, total AX, WUE DF, WUE AX and β‐glucan were generally higher (27–55% of total variance) than genotype effects (14–19%). The ara/xyl ratio of total and WUE AX showed a high influence of genotype (46 and 43% respectively). Non‐adapted rye varieties with small kernel size had the highest contents of total DF and total AX. The content of β‐glucan was positively correlated with kernel weight (r = 0.68), whereas no overall correlation was found between kernel size and the content of DF. As a conclusion, the variation in DF content and composition in this study was significantly influenced by both harvest year and rye genotype. © 2002 Society of Chemical Industry 相似文献
45.
Seawater-soluble pigments and their potential use in self-polishing antifouling paints: simulation-based screening tool 总被引:4,自引:0,他引:4
Sren Kiil Kim Dam-Johansen Claus E. Weinell Michael S. Pedersen 《Progress in Organic Coatings》2002,45(4):423-434
This work concerns the on-going development of efficient and environmentally friendly antifouling paints for biofouling control on large ocean-going ships. It is illustrated how a detailed mathematical model for a self-polishing antifouling paint exposed to seawater can be used as a product engineering tool to obtain a quick estimate of the paint behaviour that a given seawater-soluble pigment will provide. In the present context, “pigment” refers to relevant particulate solids of organic-, inorganic-, or biological nature. Simulations performed at 15 and 30 °C suggest that pigment solubility and seawater diffusivity of dissolved pigment species have a significant influence on the polishing and leaching behaviour of a typical self-polishing paint system. The pigment size distribution, on the other hand, only has a minor influence on the paint–seawater interaction. Simulations also indicate that only compounds which are effective against biofouling at very low seawater concentrations are useful as active antifouling paint ingredients. The need for model verification and exploration of practical issues, subsequent a given pigment has been found of interest, is discussed. The model approach is of relevance in the search for novel antifouling paints and for the development of accelerated test methods. 相似文献
46.
Partial Syntheses of Cardenolides and Cardenolide Analogues. XIII. Synthesis of Substituted 14,21-Epoxy-5β,14β-card-20(22)-enolide The 12-substituted 14,21-epoxy-5β,14β-card-20(22)-enolides 3 and 5 were synthesized by oxidation of the appropriate 17β-(3-furyl) derivatives 2b and 2c , respectively, with chromic acid. 5 was converted to the conjugated Δ9(11)-12-ketone 6 by dehydrogenation with selenium dioxide. The biological activities of the new compounds were investigated and are discussed. 相似文献
47.
Tingting Gu Jesper Just Katrine Tang Stenz Yan Yan Peter Sieljacks Jakob Wang Thomas Skjaerlund Groennebaek Jesper Emil Jakobsgaard Emil Rindom Jon Herskind Anders Gravholt Thomas Ravn Lassen Mathias Jrgensen Rikke Bk Eugenio Gutirrez-Jimnez Nina Kerting Iversen Peter Mondrup Rasmussen Jens Randel Nyengaard Malene Mller Jrgensen Frank de Paoli Hans Erik Btker Jrgen Kjems Kristian Vissing Kim Ryun Drasbek 《International journal of molecular sciences》2022,23(6)
Ischemic conditioning and exercise have been suggested for protecting against brain ischemia-reperfusion injury. However, the endogenous protective mechanisms stimulated by these interventions remain unclear. Here, in a comprehensive translational study, we investigated the protective role of extracellular vesicles (EVs) released after remote ischemic conditioning (RIC), blood flow restricted resistance exercise (BFRRE), or high-load resistance exercise (HLRE). Blood samples were collected from human participants before and at serial time points after intervention. RIC and BFRRE plasma EVs released early after stimulation improved viability of endothelial cells subjected to oxygen-glucose deprivation. Furthermore, post-RIC EVs accumulated in the ischemic area of a stroke mouse model, and a mean decrease in infarct volume was observed for post-RIC EVs, although not reaching statistical significance. Thus, circulating EVs induced by RIC and BFRRE can mediate protection, but the in vivo and translational effects of conditioned EVs require further experimental verification. 相似文献
48.
Fernanda Zanette da Silveira Claus Tröger Pich Elidio Angioletto Adriano Michael Bernardin 《Materials science & engineering. C, Materials for biological applications》2011,31(2):276-280
This work deals with the study of the effect of coal ashes and industrial residues in the inertness of glasses designed for industrial uses. Five formulations with four factors (residues) and constraints were used according a mixture design. The residues were dried, sieved and mixed according to the design. The formulations were melted at 1450 °C during 2 h for stabilization using 10% wt of Na2CO3 (fluxing agent). The melts were cast into a refrigerated water mold and annealed at 600 °C, and thus, the glasses were analyzed regarding their ecotoxicological effect using the Agar Diffusion Test for Escherichia coli and Staphylococcus aureus as bioindicators, comparing the results with the Artemia sp. Acute Toxicity Test. The results were studied by analysis of variance in order to determine the individual influence of each residue in the inertness of the glass system. As a final result, the ecotoxicological analysis showed that the galvanic residue makes a non-inert glass due to the high iron and zinc content of this waste. The Agar Diffusion Test is a fast and accurate technique to determine the toxicity of glass systems only for high concentration samples. 相似文献
49.
Vasileios Tzitzios Nikolaos Kostoglou Maria Giannouri Georgia Basina Christos Tampaxis Georgia Charalambopoulou Theodore Steriotis Kyriaki Polychronopoulou Charalambos Doumanidis Christian Mitterer Claus Rebholz 《International Journal of Hydrogen Energy》2017,42(37):23899-23907
A nanoporous metal–organic framework material, exhibiting an IRMOF-1 type crystalline structure, was prepared by following a direct solvothermal synthesis approach, using zinc nitrate and terephthalic acid as precursors and dimethylformamide as solvent, combined with supercritical CO2 activation and vacuum outgassing procedures. A series of advanced characterization methods were employed, including scanning electron microscopy, Fourier-transform infrared radiation spectroscopy and X-ray diffraction, in order to study the morphology, surface chemistry and structure of the IRMOF-1 material directly upon its synthesis. Porosity properties, such as Brunauer–Emmet–Teller (BET) specific area (~520 m2/g) and micropore volume (~0.2 cm3/g), were calculated for the activated sample based on N2 gas sorption data collected at 77 K. The H2 storage performance was preliminary assessed by low-pressure (0–1 bar) H2 gas adsorption and desorption measurements at 77 K. The activated IRMOF-1 material of this study demonstrated a fully reversible H2 sorption behavior combined with an adequate gravimetric H2 uptake relative to its BET specific area, thus achieving a value of ~1 wt.% under close-to-atmospheric pressure conditions. 相似文献
50.