Suppression of MHC class II expression by human class II trans-activator constructs lacking the N-terminal domain

The class II trans-activator (CIITA) is a bi- or multi-functional domain protein which plays a critical role in the expression of MHC class II genes. We report that removal of the N-terminal 151 amino acids, encompassing all of the acidic domain but leaving intact the proline/serine/threonine-rich domain, results in a mutant protein with potent suppressive properties for MHC class II expression. HeLa cells stably or transiently transfected with mutant CIITA constructs showed up to 99% suppression of MHC class II antigen induction by IFN-gamma and marked suppression of HLA-DRA mRNA expression. Transient transfection of a B lymphoma line resulted in up to 89% reduction of constitutive MHC class II expression within 5 days and suppression of HLA-DRA mRNA synthesis.     

一种多径环境下基于四阶累积量的阵列扩展测向方法

本文分析了基于四阶累积量的测向方法不能正确测量多径信号方向的原因，提出了一种多径环境下的基于四阶累积量的新型测向方法。该方法利用零点领处理方法抑制多径信号，然后采用四阶累积量进行阵列扩展测向。计算机模拟结果表明该方法在多径环境下具有良好的性能并且可能实现对足够多的信号进行测向。     

暴雨洪水流域系统随机模拟(研究之三)

本文提出的移置特大暴雨的不连序序列的随机插补方法,以及利用W—H逆变换法将偏态暴雨序列转为正态序列和随机扣除模拟的暴雨过程损失量等方法,基本是可行的,对提高模型的代表性、稳定性和实用性有重要作用。     

基于遗传算法的门限自回归模型在浅层地下水位预测中的应用

提出了建立门限自回归模型的一种简便通用的方法，用遗传算法可同时优化门限值和自回归系数．实例计算的结果说明了其可行性和有效性．该方法在各种工程时序预测中具有广泛的应用价值     

Diurnal thermal cycling effects on microwave signatures of thin seaice

To investigate effects of diurnal thermal cycles on C-band polarimetric backscatter and millimeter-wave emission from sea ice, the authors carried out a winter experiment at the outdoor geophysical research facility (GRF) in the cold regions research and engineering laboratory (CRREL), the ice sheet grew from open sea water to a thickness of 10 cm in 2.5 days, during which they took polarimetric backscatter data with a C-band scatterometer, interlaced with brightness temperature measurements at 90 GHz in conjunction with meteorological and sea ice characterizations. The initial ice growth in the late morning was slow due to high insolation. As the air temperature dropped during the night, the growth rate increased significantly. Air temperature changed drastically from about -12 to -36°C between day and night, the diurnal thermal cycle repeated itself the next day and the growth rate varied in the same manner. Ice temperature profiles clearly show the diurnal response in the ice sheet with a lag of 2.5 h behind the time of the maximum short-wave incident solar radiation. The diurnal cycles are also evident in the millimeter-wave brightness temperature data, measured sea ice backscatter revealed substantial diurnal variations up to 6 dB with repeatable cycles in synchronization with the temperature cycles and the brightness temperature modulations, the diurnal cycles in backscatter indicate that the dominant scattering mechanism related to thermodynamic processes in sea ice is reversible, a diurnal backscatter model based on sea ice electrodynamics and thermodynamics explains the observed diurnal signature. This work shows that diurnal effects are important for inversion algorithms to retrieve sea ice geophysical parameters from remote sensing data acquired with a satellite synthetic aperture radar (SAR) or scatterometer on Sun-synchronous orbits     

SQL语言中量词和空值的使用技术

在ＳＱＬ语言中可以引入全称量词符号ＦＯＲＡＬＬ，使ＳＱＬ语言使用更为自然，方便。本文讨论全称量词，存在量词和ＡＬＬ三种谓词之间的转换，联系和区别，以及空值存在时ＳＱＬ的使用技术。     

半导体激光器列阵有源区电场随电流变化的定点测量

采用连续波电光检测法，对ＧａＡｓ／ＧａＡｌＡｓ双异质结激光器列阵有源区进行定点测量，实验结果反映了发光区内及发光区外电场随电流变化的不同规律。文中对实验结果给出了合理解释。     

重Fermi子体系反常比热的理论研究

利用文献中Ｋｏｎｄｏ格子理论模型，研究了重Ｆｅｒｍｉ子体系比热与温度的反常关系。     

氧化还原功能纤维的研究 Ⅷ．含正丙胺基吸附剂与Au~（3＋）的氧化还原反应机理

通过元素分析、红外光谱分析、光电子能谱分析以及扫描电子显微镜分析等手段，证实含正丙胺基吸附剂与Ａｕ３＋的氧化还原反应过程中，氮原子邻近的羟基碳或Ｃ－Ｈ键被氧化，而氮原子并未参与氧化还原反应；吸附态Ａｕ（３＋）最终部分被还原成单质金；在非水介质中吸附在吸附剂上的金聚集成颗粒状。