Cathode-initiated breakdown in vacuum

New methods and criteria are proposed for evaluating the cathode-initiated breakdown in vacuum. Using the optimum regimes of pulse conditioning, it is possible to significantly improve the state of the cathode surface and substantially increase the electric strength with respect to cathode initiation. The proposed methods have been experimentally verified in the range of pulse durations from 10 to 800 ns.     

Development of full-scale simulators for nuclear power plants

The structure of full-scale simulators of nuclear power plants and their development are described. The special features of analytical simulators, which are economical tools for training nuclear power plant personnel because they require only a small investment of capital, are described. An industrial technology for developing simulators for nuclear power plants has been adopted and is maintained at a modern level at the All-Russia Scientific-Research Institute of Nuclear Power Plants. A change in the technical policy of the concern Rosénergoatom made it possible to solve, by and large, the problem of equipping nuclear power plants in Russia with simulators. 3 figures, 1 table, 4 references. All-Russia Scientific-Research Institute of Nuclear Power Plants. Translated from Atomnaya énergiya, Vol. 88, No. 6. pp. 407–414, June, 2000.     

Constitutive modeling of concrete in finite element analysis

Approaches generally used in defining constitutive relations for concrete are reviewed. A computer program developed for the three-dimensional finite element analysis of complex reinforced, prestressed, and refractory concrete systems is described. The constitutive models based on isotropic elastic, orthotropic elastic, and plasticity formulations, which are implemented in that program, are discussed in detail. The program incorporates nonlinear material properties, cracking in concrete, shear transfer in cracked reinforced concrete sections, and time dependent effects such as creep, shrinkage, and transient temperature distributions. A wide range of structural problems are analyzed to demonstrate the applicability of the computer program. Comparisons between predictions with different constitutive models, and between predictions and test results are made.     

The effect of granulocyte colony-stimulating factor (G-CSF) on bacterial translocation in the splenectomized rat

BACKGROUND/AIMS: We created a study group in order to investigate the effects of splenectomy and filgrastim. Filgrastim is an immunomodulator granulocyte colony-stimulating factor (G-CSF), that affects bacterial translocation. MATERIALS AND METHODS: We created 3 study groups with 30 male Sprague-Dawley rats; the first group included sham splenectomy, the second group was splenectomy, and the third group was splenectomy+ filgrastim group. RESULTS: The mean bacterial colony count of the cecum were 2.5 x 10(9) in group 1, 1.2 x 10(10) in group 2 and 3.5 x 10(9) in group 3. The differences between these groups were accepted as statistically significant. The mean counts of the terminal ileum were 1.1 x 10(9) in group 1, 5.5 x 10(10) in group 2 and 2.5 x 10(10) in group 3. The p values of group 1-2 were 0.036 (statistically significant) and 0.123 in groups 2-3) were not statistically significant. The mean counts of the liver were 0.2 x 10(4), 1 x 10(10) and 3.4 x 10(5), respectively. In comparison of the groups the p values of the first and last 2 groups were found to be 0.047 (statistically significant). The mean counts of the mesenteric lymph node were 0.7 x 10(3), 1 x 10(10) and 0.9 x 10(6) respectively. The p values were 0.343 for the first and the last 2 groups both. As they were above 0.05, they were not statistically significant. The degrees of liver Kupffer cell hyperplasia were (+) 40%, (+2) 50% and (+3) 10% (group 1), (+) 10%, (+2) 40% and (+3) 50% (group 2), (+2) 60% and (+3) 40% (group 3) (p = 0.0039). The rates of the absence of pathology in mesenteric lymph nodes were 70% (group 1), 90% (group 2) and 100% (group 3) (p = 0.049). These findings were statistically significant. CONCLUSIONS: We found that splenectomy has activated the whole predisposing factors of bacterial translocation and created the latter itself. In addition, we showed that filgrastim, a recently widespread used G-CSF, decreases bacterial translocation significantly.     

REFORMULATING QUADRATIC ASSIGNMENT PROBLEMS FOR EFFICIENT OPTIMIZATION

Decision making problems in areas such as R&D project selection, facility layout design, capital budgeting, resource allocation, communication network design, and scheduling are more than often formulated as assignment problems with quadratic objective functions in 0-1 variables. Although quadratic assignment problems are formulated as mathematical optimization problems, the solution algorithms that have been suggested in the literature are usually heuristic. The scarcity of exact solution techniques is attributed to the presence of large numbers of 0-1 variables as well as to the optimization of a nonlinear objective function expressed in 0-1 variables. This paper suggests a reformulation method that linearizes the quadratic objective functions in assignment problems and reduces the number of 0-1 variables one has to deal with in the optimization process. The new reformulation leads to use of commercially available codes to solve the resulting mixed-integer linear programming problem. Computational experience with this new reformulation is also discussed.     

Numerical modeling of reinforced concrete containment walls under cyclic shear

This paper provides an overview of research in numerical modeling of reinforced concrete containment walls subjected to cyclic shear. Bases for the development of the model are discussed, and application of the model is shown. Further research needs and interests are suggested for improved analysis capabilities and design.     

Sensitivity and specificity of infrared thermography in detection of subclinical mastitis in dairy cows

The objectives of this experiment were to determine interrelationships among mastitis indicators and evaluate the subclinical mastitis detection ability of infrared thermography (IRT) in comparison with the California Mastitis Test (CMT). Somatic cell count (SCC), CMT, and udder skin surface temperature (USST) data were compiled from 62 Brown Swiss dairy cows (days in milk = 117 ± 51, milk yield = 14.7 ± 5.2 kg; mean ± SD). The CORR, REG, and NLIN procedures of Statistical Analysis System (SAS Institute Inc., Cary, NC) were employed to attain interrelationships among mastitis indicators. The diagnostic merit of IRT as an indirect measure of subclinical mastitis was compared with CMT using the receiver operating characteristics curves. The udder skin surface temperature was positively correlated with the CMT score (r = 0.86) and SCC (r = 0.73). There was an exponential increase in SCC (SCC, ×10³ cells/mL = 22.35 × e^{1.31 × CMT score}; R² = 0.98) and a linear increase in USST (USST, °C = 33.45 + 1.08 × CMT score; R² = 0.75) as the CMT score increased. As SCC increased, USST increased logarithmically [USST, °C = 28.72 + 0.49 × ln(SCC, ×10³ cells/mL); R² = 0.72]. The USST for healthy quarters (SCC ≤400,000 cells/mL; n = 94) was different from that for subclinical mastitic quarters (SCC >400,000 cells/mL; n = 135) (mean ± SE; 33.45 ± 0.09 vs. 35.80 ± 0.08°C). The sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, positive predictive value, and negative predictive value were 95.6, 93.6, 14.97, 0.05, 95.0, and 93.6, respectively, for IRT and 88.9, 98.9, 83.56, 0.11, 99.2, and 86.1, respectively, for CMT. The area under the receiver operating characteristics curve for IRT and CMT was not different. In conclusion, as a noninvasive and quick tool, IRT can be employed for screening subclinical mastitis via measuring USST, with a high predictive diagnostic ability similar to CMT when microbiological culturing is unavailable. However, the reliability of IRT among cows with different characteristics and those living under various environmental conditions remains to be determined.     

Antibacterial Silicone-Urea/Organoclay Nanocomposites

Montmorillonite modified with distearyldimethyl ammonium chloride (C18-QAC) (Nanofil-15) (NF15) was incorporated into polydimethylsiloxane-urea (silicone-urea, PSU) copolymers. PSU was obtained by the reaction of equimolar amounts of aminopropyl terminated polydimethylsiloxane (PDMS) oligomer (<M_n> = 3,200 g/mol) and bis(4-isocyanatohexyl)methane (HMDI). A series of PSU/NF15 nanocomposites were prepared by solution blending with organoclay loadings ranging from 0.80 to 9.60% by weight, corresponding to 0.30 to 3.60% C18-QAC. Colloidal dispersions of organophilic clay (NF15) in isopropanol were mixed with the PSU solution in isopropanol and were subjected to ultrasonic treatment. Composite films were obtained by solution casting. FTIR spectroscopy confirmed that the organoclay mainly interacted with the urea groups but not with PDMS. XRD analysis showed that nanocomposites containing up to 6.40% by weight of organoclay had fully exfoliated silicate layers in the polymer matrix, whereas 9.60% loading had an intercalated structure. Physicochemical properties of nanocomposites were determined. PSU/NF15 nanocomposites displayed excellent long-term antibacterial properties against E. coli.