Contingent reinforcement of marijuana abstinence among individuals with serious mental illness: A feasibility study.

The feasibility of using monetary incentives to promote abstinence from marijuana use among individuals with serious mental illness was examined by using a within-subjects experimental design. Participants were 18 adults with schizophrenia or other serious mental illness who reported regular marijuana use. During 2 baseline conditions, participants received payment for submitting urine specimens independent of urinalysis results. During 3 incentive conditions, participants received varying amounts of money if urinalysis results were negative for recent marijuana use. The number of marijuana-negative specimens obtained was significantly greater during incentive than baseline conditions. These results provide evidence that marijuana use among at least some mentally ill individuals is sensitive to contingent reinforcement and support the potential feasibility of using contingency management interventions to reduce substance abuse among the mentally ill. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Atomic Bond Deficiency Defects in Amorphous Metals

Atomic bond deficiency (BD) is considered to be characteristic structural defects in amorphous metals. They are the necessary feature of local atomic configurations that facilitate various atomic transports under different driving forces. Compared with vacancies in crystalline solids, they are ??small?? in terms of their formation energies, volume costs, and elementary steps involved in atomic transport. This article reviews the authors?? recent efforts made to analyze how various local configurations containing BD are related to amorphous metal??s unique characteristics, such as glass transition, diffusion, shear flow, and structural relaxation.     

Modelling the leaching of Pb, Cd, As, and Cr from cementitious waste using PHREEQC

A leaching model was developed using the United States Geological Survey public domain PHREEQC geochemical package to simulate the leaching of Pb, Cd, As, and Cr from cementitious wastes. The model utilises both kinetic terms and equilibrium thermodynamics of key compounds and provides information on leachate and precipitate speciation. The model was able to predict the leaching of Pb, Cd, As, and Cr from cement in the presence of both simple (0.1 and 0.6M acetic acid) and complex municipal landfill leachates. Heavy metal complexation by the municipal landfill leachate was accounted for by the introduction of a monoprotic organic species into the model. The model indicated Pb and As were predominantly incorporated within the calcium silicate hydrate matrix while a greater portion of Cd was seen to exist as discrete particles in the cement pores and Cr (VI) existed mostly as free CrO4(2-) ions. Precipitation was found to be the dominant mechanism controlling heavy metal solubility with carbonate and silicate species governing the solubility of Pb and carbonate, silicate and hydroxide species governing the solubility of Cd. In the presence of acetic acid, at low pH values Pb and Cd acetate complexes were predominant whereas, at high pH values, hydroxide species dominated. At high pH values, the concentration of As in the leachate was governed by the solubility of Ca3(AsO4)2 with the presence of carbonate alkalinity competing with arsenate for Ca ions. In the presence of municipal landfill leachate, Pb and Cd organic complexes dominated the heavy metal species in solution. The reduction of As and Cr in municipal landfill leachate was crucial for determining aqueous speciation, with typical municipal landfill conditions providing the reduced forms of As and Cr.     

Thiol–Ene Clickable Gelatin: A Platform Bioink for Multiple 3D Biofabrication Technologies

Bioprinting can be defined as the art of combining materials and cells to fabricate designed, hierarchical 3D hybrid constructs. Suitable materials, so called bioinks, have to comply with challenging rheological processing demands and rapidly form a stable hydrogel postprinting in a cytocompatible manner. Gelatin is often adopted for this purpose, usually modified with (meth‐)acryloyl functionalities for postfabrication curing by free radical photopolymerization, resulting in a hydrogel that is cross‐linked via nondegradable polymer chains of uncontrolled length. The application of allylated gelatin (GelAGE) as a thiol–ene clickable bioink for distinct biofabrication applications is reported. Curing of this system occurs via dimerization and yields a network with flexible properties that offer a wider biofabrication window than (meth‐)acryloyl chemistry, and without additional nondegradable components. An in‐depth analysis of GelAGE synthesis is conducted, and standard UV‐initiation is further compared with a recently described visible‐light‐initiator system for GelAGE hydrogel formation. It is demonstrated that GelAGE may serve as a platform bioink for several biofabrication technologies by fabricating constructs with high shape fidelity via lithography‐based (digital light processing) 3D printing and extrusion‐based 3D bioprinting, the latter supporting long‐term viability postprinting of encapsulated chondrocytes.     

Some Grubbs-Type Statistics for the Detection of Several Outliers

Several widely used tests for outlying observations are reviewed. Problems of repeated application and “masking” are described. Suggested as appropriate to over-come these problems are two new statistics: L_k which is based on the k largest (observed) values and E_k which is based on the k largest (in absolute value) residuals. Tables of approximate critical values for these statistics are given for 0.01, .025,0.05, and 0.10 levels of significance and for sample size n = 3 (1) 20 (5) 50.     

The Columbia University sub-micron charged particle beam

A lens system consisting of two electrostatic quadrupole triplets has been designed and constructed at the Radiological Research Accelerator Facility (RARAF) of Columbia University. The lens system has been used to focus 6 MeV ⁴He ions to a beam spot in air with a diameter of 0.8 μm. The quadrupole electrodes can withstand voltages high enough to focus ⁴He ions up to 10 MeV and protons up to 5 MeV. The quadrupole triplet design is novel in that alignment is made through precise construction and the relative strengths of the quadrupoles are accomplished by the lengths of the elements, so that the magnitudes of the voltages required for focusing are nearly identical. The insulating sections between electrodes have had ion implantation to improve the voltage stability of the lens. The lens design employs Russian symmetry for the quadrupole elements.     

Genetic subsets regression

Subset regression procedures have been shown to provide better overall performance than stepwise regression procedures. However, due to the combinatorial nature of evaluating each potential subset, subset regression techniques are costly to use. To resolve this difficulty, the use of a simple genetic algorithm (GA) is proposed to reduce the number of subsets which must be evaluated. Any of a number of popular criteria, including Mallows' C_p, MSE, R², AIC, etc., can be used to drive the search strategy associated with the use of the GA. Several illustrated examples on its use are provided.     

My personal history in the early explorations of computer graphics

Gary Demos discovered computer graphics while hearing a computer-generated film presentation at CalTech in 1970 by John Whitney Sr. Gary then began working under the direction of Ivan Sutherland in Utah to develop early computer graphics hardware and software. In 1974 Gary and John Whitney Jr. started the “Motion Picture Project” at Information International to produce computer generated simulated scenes for movies (Futureworld, Looker, and Tron) and commercials. These early computer-generated visuals were quite challenging given the level of software and hardware technology available in the 1970’s. In 1981 Gary and John left Information International to form Digital Productions, where they produced effects for the movies Last Starfighter and “2010”, which were both released in 1984. Digital Productions used the Cray XMP computer, together with the Digital Film Printer that they had developed at Information International. Following a hostile takeover by Omibus of Digital Productions in 1986, Whitney/Demos Productions was formed, using a Thinking Machine parallel computer. This paper describes the technical challenges and achievements of this early visual computing.     

An Adaptable Oscillator-Based Controller for Autonomous Robots

This paper proposes a unique oscillator-based robot controller with learning abilities to effectively guide a team of robots operating in uncertain environments. To verify this, we designed four separate controllers and compared their performance in a series of tests in several different environments. The experiments used a team of three robots to explore arenas with variable lighting and different obstacle patterns, with a goal of having the team as a whole absorb as much light as possible. The four controllers were: a reactive controller, an oscillator with fixed parameters, an oscillator whose parameters changed based on the pattern of sensor information received, and an oscillator-based controller that used reinforcement learning. Experiments confirmed that the proposed method outperforms the others in all environments tested. This material is based upon work supported in part by the U.S. Army Research Office under grant/contract number DAAG55-98-1-0011.     

A multi-institutional, multinational study of programming concepts using card sort data

Abstract: This paper presents a case study of the use of a repeated single‐criterion card sort with an unusually large, diverse participant group. The study, whose goal was to elicit novice programmers' knowledge of programming concepts, involved over 20 researchers from four continents and 276 participants drawn from 20 different institutions. In this paper we present the design of the study and the unexpected result that there were few discernible systematic differences in the population. The study was one of the activities of the National Science Foundation funded Bootstrapping Research in Computer Science Education project (2003).