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1.
I Panfoli F Rosina L Musante A Morelli C Cugnoli IM Pepe 《Canadian Metallurgical Quarterly》1995,44(5):247-257
Active Ca2+ transport was measured in microsomal vesicles prepared from bovine retinae and was compared with that in disk membranes of the photoreceptor cells of the same retina. The 45Ca uptake was dependent on the presence of Mg(2+)-ATP and was inhibited by vanadate or when GTP substituted for ATP. The dependence of calcium uptake on the external free Ca2+ concentration gave a KM = 13 microM or a KM = 0.1 microM for disks and microsomal vesicles, respectively. A phosphorylated intermediate (E-P) of Ca(2+)-ATPase of about 100 kDa was isolated in microsomal vesicles. The E-P formation was strongly inhibited by thapsigargin and partially by 2,5-di-(-butyl)benzohydroquinone. Digestion of disks or microsomes with calpain had no effect on the phosphorylated intermediate, while digestion with trypsin produced two fragments of approximately 55 kDa and 35 kDa. These results suggest that bovine retinal microsomes contain a calcium pump belonging to the SERCA family. 相似文献
2.
3.
Guilherme T. de Assis Alberto H. F. Laender Marcos André Gonçalves Altigran S. da Silva 《World Wide Web》2009,12(3):285-319
Focused crawlers have as their main goal to crawl Web pages that are relevant to a specific topic or user interest, playing
an important role for a great variety of applications. In general, they work by trying to find and crawl all kinds of pages
deemed as related to an implicitly declared topic. However, users are often not simply interested in any document about a
topic, but instead they may want only documents of a given type or genre on that topic to be retrieved. In this article, we
describe an approach to focused crawling that exploits not only content-related information but also genre information present
in Web pages to guide the crawling process. This approach has been designed to address situations in which the specific topic
of interest can be expressed by specifying two sets of terms, the first describing genre aspects of the desired pages and
the second related to the subject or content of these pages, thus requiring no training or any kind of preprocessing. The
effectiveness, efficiency and scalability of the proposed approach are demonstrated by a set of experiments involving the
crawling of pages related to syllabi of computer science courses, job offers in the computer science field and sale offers
of computer equipments. These experiments show that focused crawlers constructed according to our genre-aware approach achieve
levels of F1 superior to 88%, requiring the analysis of no more than 65% of the visited pages in order to find 90% of the
relevant pages. In addition, we experimentally analyze the impact of term selection on our approach and evaluate a proposed
strategy for semi-automatic generation of such terms. This analysis shows that a small set of terms selected by an expert
or a set of terms specified by a typical user familiar with the topic is usually enough to produce good results and that such
a semi-automatic strategy is very effective in supporting the task of selecting the sets of terms required to guide a crawling
process. 相似文献
4.
We investigate the temporal intensity noise characteristics of analog liquid-crystal-based spatial light modulators and how they affect the device's achievable discrete numeric accuracies in an optical computing system. First we present an analytical development that defines the concept of precision in analog computing systems, then we define a noise metric and a precision-optimal quantizer for determining the discrete numeric characteristics of the devices. Second we present an experimental discussion in which a low-noise test facility constructed for this investigation is described, and the noise characteristics of three commercially available liquid-crystal-based modulators are measured and analyzed. The accuracy implications of this measured noise are then discussed within the context of the analytical model for each modulator. 相似文献
5.
Guilherme Ferreira Gomes Camila Aparecida Diniz Sebastião Simões da CunhaJr. Antonio Carlos AncelottiJr. 《Journal of Failure Analysis and Prevention》2017,17(4):740-749
The investigation of possible failures in composite materials is a matter of very great importance, and the Tsai-Wu criterion is an effective criterion for analyzing those flaws in anisotropic materials and defining whether the material at a given load will or will not suffer structural failure. In this study, an optimization procedure is proposed to minimize the maximum value of Tsai-Wu of laminated composite tubes subject to axial loading. Artificial neural networks and genetic algorithms are chosen as optimization tools. The results of this study show that the developed algorithm converges faster. Then, the maximum Tsai-Wu value is used as the objective function and the fiber orientations are the constraints in the optimization process. The results yielded by them are compared and discussed. Optimal results are compared with respect to the usual initial design. The design approach is recommended for structures where composites are the key load-carrying members such as orthopedic prosthesis. 相似文献
6.
Caroline ConcattoAuthor VitaeJoão AlmeidaAuthor Vitae Guilherme FachiniAuthor VitaeMarcos HervéAuthor Vitae Fernanda KastensmidtAuthor Vitae Érika CotaAuthor VitaeMarcelo LubaszewskiAuthor Vitae 《Journal of Parallel and Distributed Computing》2011,71(5):664-674
We propose an effective and low cost method to increase the yield and the lifetime of torus NoCs. The method consists in detecting and diagnosing NoC interconnect faults using BIST structures and activating alternative paths for the faulty links. Alternative paths use the inherent redundancy of the torus topology, thus leading to minimal performance, area, and power overhead. We assume an extended interconnect fault model comprising stuck-at and pairwise shorts within a single link or between any two links in the network. Experimental results for a 3×3 NoC show that the proposed approach can correctly diagnose 93% of all possible interconnect faults and can mitigate 42% of those faults (representing 94.4% of the solvable faults) with a worst case performance penalty of 8% and 1% of area overhead. We also demonstrate the scalability of the method by presenting its application to larger NoCs. 相似文献
7.
8.
Arilo Claudio Dias-Neto Guilherme Horta Travassos 《Information and Software Technology》2009,51(11):1487-1504
Selecting software technologies for software projects represents a challenge to software engineers. It is known that software projects differ from each other by presenting different characteristics that can complicate the selection of such technologies. This is not different when considering model-based testing. There are many approaches with different characteristics described in the technical literature that can be used in software projects. However, there is no indication as to how they can fit a software project. Therefore, a strategy to select model-based testing approaches for software projects called Porantim is fully described in this paper. Porantim is based on a body of knowledge describing model-based testing approaches and their characterization attributes (identified by secondary and primary experimental studies), and a process to guide by adequacy and impact criteria regarding the use of this sort of software technology that can be used by software engineers to select model-based testing approaches for software projects. 相似文献
9.
SAR interferometry based on Permanent Scatterers (PS-InSAR™) is used here to study the present crustal mobility of a large area of NW Italy, in the Piemonte region.Thirty-eight satellite scenes (ERS SAR), taken from May 1992 to January 2001, were analysed for detecting more than 2 million PS on the study area. Continuous velocity surface maps (Iso-Kinematic Maps: IKM) were obtained from geo-statistical and spatial cluster techniques (Hot Spot analysis) of PS “short-period” data, to identify relative ground motions and to compare them with “long-period” tectonic mobility trends, i.e. those inferred at regional scale over geological times (some million years).The comparison was made by individuation of homogeneous kinematic areas, represented in the IKM, and characterization of the boundaries between them (Iso-Kinematic Boundaries: IKB). The IKB were used as tools to asses if the PS-InSAR data on present-day crustal mobility could fit with the distribution of real tectonic structures or field geological elements.IKM were drawn for uplifting geological sectors of Piemonte (Maritime Alps, Gran Paradiso, Langhe) where moderate to very low seismicity is recorded, and gravitational instabilities of rock mass on mountain slopes are widespread. The land sectors have been chosen in order to test the suitability of IKM in very different geo-morphological conditions.Different types of correspondence between the IKM and the geological kinematic trend were found:
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- a first type in which the kinematic trend of short-period (a decade of years, i.e. the PS-InSAR detection time span) is in agreement with a long-period tectonic trend (some million years) and seem to be driven by well known faults subparallel to the IKB. These kinematic trends can be hidden by the slope movement due to gravitational instabilities;
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- a second type in which the kinematic trend of short-period does not strictly correspond to the long-period trend, but can be considered as minor-order, uplifting-subsidence cycles, even if in contrast with the long-period kinematic trend. Alternatively, the short-period kinematic trends could reflect the action of deep-seated geological forces or structures, not yet known or inferable (at least with the recorded PS-InSAR velocities) on the basis of the available geological data and models.
10.
Celina M.H. de Figueiredo Guilherme D. da Fonseca Vinicius G.P. de Sa Jeremy Spinrad 《Algorithmica》2006,46(2):149-180
A homogeneous set is a non-trivial module of a graph, i.e. a non-empty,
non-unitary, proper subset of a graph's vertices such that all its elements
present exactly the same outer neighborhood. Given two graphs
the Homogeneous Set Sandwich Problem (HSSP) asks whether there
exists a sandwich graph
which
has a homogeneous set. In 2001 Tang et al. published
an all-fast
algorithm which was recently proven wrong, so that the HSSP's known upper bound would have been reset
thereafter at the former
determined by Cerioli et al. in 1998. We present, notwithstanding, new deterministic
algorithms which have it established at
We give as
well two even faster
randomized algorithms, whose simplicity might
lend them didactic usefulness. We believe that, besides providing efficient
easy-to-implement procedures to solve it, the study of these new approaches
allows a fairly thorough understanding of the problem. 相似文献