A case of coronary artery bypass grafting for effort angina in a patient with post skin grafting for an extramammary Paget's disease

The extramammary Paget's disease of anogenital area is rare, and is seen as a precancerous lesion or carcinoma in situ. In most cases, surgical treatment including dissection of regional lymph nodes, skin resection and grafting should be considered first. A 74-year-old male suffered from effort angina and underwent triple coronary artery bypass grafting (CABG) including saphenous vein graft (SVG) harvested from right lower leg. Five years previously he underwent skin grafting for extramammary Paget's disease of both inguinal areas and the perineal area. The postoperative course was uneventful and he was discharged 23 days after the CABG operation. Extramammary Paget's disease is localized in epidermis for years and there has been no report of direct invasion into vessels. Therefore, there appears to be no reason not to use an SVG if there is no luminal thrombus or occlusion.     

Asymmetric anionic polymerization of n-diphenyl-methylitaconimide with chiral ligand-organometal complex

Summary Asymmetric anionic polymerizations of achiral N-diphenylmethylitaconimide (DPII) were performed with chiral ligand — organometal complexes in toluene. The obtained poly(DPII)s exhibited molecular weights of 1.5 × 10³ to 6.3 × 10³ and specific rotation between +7.5 to −18.4° (THF). The chirality of polymer was significantly affected by the organometals and chiral ligands. The poly(DPII) obtained with (4S)-2,2′-(1-ethylpropylidene)bis(4-benzyl-4,5-dihydrooxazole) (Bnbox) / n-butyllithium (n-BuLi) exhibited the highest specific rotation (−18.4°). The optical activities of the poly(DPII)s were attributed to configurational chirality of the main chain more than conformational chirality, judged from NMR, circular dichroism (CD) and GPC analyses using UV and polarimetric detectors. Received: 10 January 2002/ Revised: 12 April 2002/ Accepted: 22 April 2002     

由紧凑型高dI／dt门极驱动单元驱动的新型对称门极换流晶闸管

在工业大功率应用领域已经推出了多种类型（对称，非对称以及逆向导通）的门极换流晶闸管（GCT）器件，为了用它来实现更高性能、更加合适的系统，人们期望对门极换流晶闸管展开进一步的研究，本文提出了对称门极换流晶闸管的一种新方案。     

Study of asynchronizing phenomena using generator model with field mutual leakage reactance

This paper describes the effect of mutual leakage reactance in the rotor circuit on the analysis of generator transient characteristics. The authors derive a detailed equivalent circuit model for a 48P‐15,750‐kVA generator, analyze sudden short circuits and asynchronization phenomena of the generator by simulations with an electromagnetic transients program (ATP‐EMTP), and compare the results with experimental data. © 2005 Wiley Periodicals, Inc. Electr Eng Jpn, 153(3): 31–40, 2005; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/eej.20147     

Association between Ala54Thr substitution of the fatty acid-binding protein 2 gene with insulin resistance and intra-abdominal fat thickness in Japanese men

In insulin-dependent diabetes mellitus (IDDM), inappropriate growth hormone (GH) responses to several stimuli, including GH-releasing hormone (GHRH), have been described. A decreased hypothalamic somatostatinergic tone is one of the most likely explanations for these findings. His-DTrp-Ala-Trp-DPhe-Lys-NH2 [GH-releasing peptide-6 [GHRP-6]] is a synthetic hexapeptide that stimulates GH release in vitro and in vivo. The mechanism of action of GHRP-6 is unknown, but it probably does not inhibit hypothalamic somatostatin secretion. Also, GHRH and GHRP-6 apparently activate different intracellular pathways to release GH. The aim of this study was to evaluate whether there is a differential effect of IDDM on GHRP-6- and GHRH-induced GH secretion. Six patients with IDDM and seven control subjects were studied. Each subject received GHRP-6 (1 microgram/kg intravenously [IV]), GHRH (100 micrograms IV), and GHRP-6 + GHRH on 3 separate days. GH peak values (mean +/- SE in micrograms per liter) were similar in controls and diabetics after GHRH (22.5 +/- 7.8 v 24.0 +/- 9.7) and after GHRP-5 (20.5 +/- 5.3 v 24.4 +/- 6.3). The association of GHRP-6 and GHRH induced a significantly higher GH release than administration of the isolated peptides in both groups. The synergistic GH response to combined administration of GHRP-6 and GHRH was not different in controls (70.5 +/- 20.0) and diabetics (119.0 +/- 22.2). In summary, the effectiveness of GHRP-6 in IDDM could reinforce the evidence that this peptide probably does not release GH through a decrease in hypothalamic somatostatin secretion. Moreover, our data suggest that both GHRH and GHRP-6 releasing mechanisms are unaltered in IDDM.     

Infective endocarditis with a huge mitral vegetation related to atopic dermatitis and high serum level of infection-related antiphospholipid antibody: a case report]

A 24-year-old woman with atopic dermatitis was admitted to our hospital with fever. Echocardiography showed a huge vegetation attached to the posterior mitral commissure without mitral valve dysfunction. Blood culture identified methicillin-sensitive Staphylococcus aureus. The serum level of antiphospholipid antibody was elevated. A splenic infarction occurred on the second hospital day. Surgery to resect the residual mobile vegetation was performed uneventfully on the 6th hospital day. The postoperative course was uneventful, and the patient was discharged after 4 weeks of antibiotic therapy. Preservation of the mitral valve is rare in the face of virulent Staphylococcus infection and the presence of a huge mobile vegetation. These findings were apparently related to the high serum level of infection-related antiphospholipid antibody and atopic dermatitis.     

Built-in folded monopole antenna for handsets

A built-in folded monopole antenna for handsets (BFMA) is introduced and investigated. The characteristics of the BFMA are compared with those of a planar inverted-F antenna (PIFA), which is one of the conventional handset antennas. As a result, it has been confirmed that the BFMA has smaller size and wider bandwidth compared with the PIFA.     

Contributions of generators for power flow and loads in a power system

Because of the introduction of deregulation and competition in the electricity supply industry, large numbers of IPPs (Independent Power Producers) will get into the market. It has become much more important to be able to determine which generators are supplying a particular load, which generator is responsible for transmission line congestion, and what is each generator's contribution to the system losses. In this paper, we propose a way to calculate these contributions automatically. The applicability of the proposed technique is demonstrated using the EAST 10 47‐bus power system. © 2003 Wiley Periodicals, Inc. Electr Eng Jpn, 144(3): 28–35, 2003; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/eej.10181     

An alternative procedure to intra-arterial aortoinfundibuloplasty

Intra-arterial aortoinfundibuloplasty is a newly developed aortic annular enlargement procedure in which, originally, the annulus was split anteriorly via the main pulmonary arteriotomy. An alternative method of aortoinfundibuloplasty was studied experimentally which creates spiral incisions on the free walls of both great arteries descending together into the aortopulmonary and infundibular septum via both commissures of right and left facing cusps of pulmonary and aortic valves. The valve prosthesis is implanted through this three-dimensional incision, followed by patch reconstruction. The ratio of annular augmentation was three sizes in two animals and four sizes in three animals. Immediate postoperative haemodynamics were satisfactory and there was no significant postoperative increase in systolic pressure gradient at the right ventricular outflow tract and in the right ventricular end-diastolic pressure. This alternative procedure could be applied to cases requiring radical annular enlargement and would give a wider view of both ventricular outflow tracts.