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81.
Manqi Zhang Degang Li Tianbao Dong Xiaoxiao Hou Xiao Zhang Hongliang Liu Lihong Liu Shouyu Tang Shaomin Liu 《乙烯基与添加剂工艺杂志》2021,27(3):519-532
Global bacterial infections associated with conventional polyvinyl chloride (PVC) medical devices place a heavy burden on healthcare systems and thus it will be desirable if medical devices are made from antimicrobial PVC. There are numerous studies focusing on polymer surface modifications to either leach antimicrobial agents or kill pathogenic microbes upon direct contact. In this work, mannitol fumarate ester-based aluminum metal alkoxide (MFE-Al) additive was developed to confer simultaneously improved antibacterial property and enhanced high temperature sterilization resistance of the resultant PVC. Data obtained confirm that the MFE-Al stabilized PVC sheets significantly inhibit 98% bacterial growth. They also show biocompatibility with cultured H9C2 cardiomyocytes and hemocompatibility in vitro. Dry heat sterilization is generally not suitable for PVC medical wares due to their poor thermal compatibility. Surprisingly, our antimicrobial-biocompatible PVC can maintain stability at 180°C for 90 min. Such a high thermal stability indicates the MFE-Al stabilized PVC can endure 90 cycles of dry-heat sterilization without significant damage. This study may provide a solution to reduce PVC medical waste for a maximum benefit without compromising human health or the environment. 相似文献
82.
Yi Zhang Jianzi Huang Qiongzhao Hou Yujuan Liu Jun Wang Shulin Deng 《International journal of molecular sciences》2021,22(7)
Salt stress is a major increasing threat to global agriculture. Pongamia (Millettia pinnata), a semi-mangrove, is a good model to study the molecular mechanism of plant adaptation to the saline environment. Calcium signaling pathways play critical roles in the model plants such as Arabidopsis in responding to salt stress, but little is known about their function in Pongamia. Here, we have isolated and characterized a salt-responsive MpCML40, a calmodulin-like (CML) gene from Pongamia. MpCML40 protein has 140 amino acids and is homologous with Arabidopsis AtCML40. MpCML40 contains four EF-hand motifs and a bipartite NLS (Nuclear Localization Signal) and localizes both at the plasma membrane and in the nucleus. MpCML40 was highly induced after salt treatment, especially in Pongamia roots. Heterologous expression of MpCML40 in yeast cells improved their salt tolerance. The 35S::MpCML40 transgenic Arabidopsis highly enhanced seed germination rate and root length under salt and osmotic stresses. The transgenic plants had a higher level of proline and a lower level of MDA (malondialdehyde) under normal and stress conditions, which suggested that heterologous expression of MpCML40 contributed to proline accumulation to improve salt tolerance and protect plants from the ROS (reactive oxygen species) destructive effects. Furthermore, we did not observe any measurable discrepancies in the development and growth between the transgenic plants and wild-type plants under normal growth conditions. Our results suggest that MpCML40 is an important positive regulator in response to salt stress and of potential application in producing salt-tolerant crops. 相似文献
83.
Wei-Chieh Huang Kao-Chang Lin Chih-Wei Hsia Chih-Hsuan Hsia Ting-Yu Chen Periyakali Saravana Bhavan Joen-Rong Sheu Shaw-Min Hou 《International journal of molecular sciences》2021,22(7)
Platelets play a crucial role in the physiology of primary hemostasis and pathological processes such as arterial thrombosis; thus, developing a therapeutic target that prevents platelet activation can reduce arterial thrombosis. Pterostilbene (PTE) has remarkable pharmacological activities, including anticancer and neuroprotection. Few studies have reported the effects of pterostilbene on platelet activation. Thus, we examined the inhibitory mechanisms of pterostilbene in human platelets and its role in vascular thrombosis prevention in mice. At low concentrations (2–8 μM), pterostilbene strongly inhibited collagen-induced platelet aggregation. Furthermore, pterostilbene markedly diminished Lyn, Fyn, and Syk phosphorylation and hydroxyl radical formation stimulated by collagen. Moreover, PTE directly hindered integrin αIIbβ3 activation through interfering with PAC-1 binding stimulated by collagen. In addition, pterostilbene affected integrin αIIbβ3-mediated outside-in signaling, such as integrin β3, Src, and FAK phosphorylation, and reduced the number of adherent platelets and the single platelet spreading area on immobilized fibrinogen as well as thrombin-stimulated fibrin clot retraction. Furthermore, pterostilbene substantially prolonged the occlusion time of thrombotic platelet plug formation in mice. This study demonstrated that pterostilbene exhibits a strong activity against platelet activation through the inhibition of integrin αIIbβ3-mediated inside-out and outside-in signaling, suggesting that pterostilbene can serve as a therapeutic agent for thromboembolic disorders. 相似文献
84.
界面性能对复合驱提高采收率有重大的影响,界面张力越低,洗油效率越高;Zeta电位越高,油水乳状液越稳定。研究了各类无机盐对新疆油田复合驱界面性能的影响。结果显示,Zeta电位的绝对值随着无机盐浓度的增高而增大;无机碱中,碳酸根离子降低界面张力效果最好,氢氧根次之,碳酸氢根最差;阳离子中,钾离子降低界面张力效果最好,其次是钠离子,镁离子会略微提高界面张力,钙离子则会大幅度提高界面张力;阴离子中,与硫酸根相比,氯离子能更好地降低界面张力。通过以上研究,确定了Q站污水处理站外排水更适合三元复合驱配液。 相似文献
85.
对 150 mm 厚 SA387Gr22C12 钢板( / % : 0.13 ~0.14C,0.09Si,0.55 ~0.56Mn,0.004P,0.001S,2.48 ~2. 49Cr,1.11~1.12Mo) 模拟焊后拉伸性能、-29 ℃ 冲击性能、金相组织及回火脆化倾向评定等进行试验,并检测了交货态(正火 + 回火) 、最小模拟焊后态、最大模拟焊后态及步冷试验后的钢板各项性能指标 。结果表明,钢板的回火脆化 倾向不明显,其结果 CvTr55 + 2.5ΔCvTr55 为-63 ℃,完全满足甲醇合成塔用钢板的技术要求。 相似文献
86.
研究了Mg-Sr牺牲阳极的显微组织和电化学性能的特征.结果表明,Mg-Sr牺牲阳极的晶粒尺寸随Sr含量的增加而减小;当Sr质量分数为0.19%时,电流效率达到58.56%,开路电位达到-1.735 VSCE;Sr的质量分数再增加,Mg-Sr阳极的电流效率降低,开路电位正移.研究认为,Sr的质量分数为0.19%时,晶界析出的Mg17Sr2相(弱阴极相)和α-Mg基体(阳极相)组成电偶对,阻碍了阳极晶间腐蚀,减少了晶粒大块脱落, 且Sr能够和Mg、Fe形成弱阴极性化合物降低Fe的危害,电流效率升高,同时晶粒细化,晶界面积变大,杂质相分布更均匀,开路电位负移;Sr含量大于0.19%时,过量的Mg17Sr2相作为阴极相加大了阳极的自腐蚀,电流效率下降,开路电位正移. 相似文献
87.
M.L. Zhang Y.D. Yan Z.Y. Hou L.A. Fan Z. Chen D.X. Tang 《Journal of Alloys and Compounds》2007,440(1-2):362-366
Mg–Li alloys have been prepared by electrolysis in a molten salt electrolyte of 50% LiCl–50% KCl (mass%) at low temperature of 420–510 °C. The effects of electrolytic temperature and cathodic current density on alloy formation rate and current efficiency were studied. For the deposition of metallic lithium on the cathode consisting of solid Mg and liquid Mg–Li, both electrolytic temperature and cathodic current density have no obvious influence on current efficiency; while for the deposition of metallic lithium on the solid magnesium cathode, both electrolytic temperature and cathodic current density greatly affect alloy formation rate and current efficiency. The optimum electrolysis condition is—molten salt mixture, LiCl:KCl = 1:1 (mass%), electrolytic temperature: 480 °C, cathode current density: 1.13 A cm−2. Mg–Li alloys with low lithium content (about 25 wt% Li) were prepared via electrolysis at low temperature following by thermal treatment at higher temperature. 相似文献
88.
实验以三氯化镓为原料,柠檬酸为络合剂,通过NH3·H2O调节pH值,得到透明稳定的前躯体溶胶,红外光谱分析表明上述溶胶在向凝胶转变过程中,发生镓与柠檬酸的络合,并在干燥过程中依靠氢键形成大分子聚合物.采用提拉涂覆溶胶-凝胶法在多晶氧化铝基片表面形成凝胶膜后,经800℃下热处理,凝胶膜转化为单斜相β-氧化镓陶瓷薄膜.重复镀膜和热处理及超声清洗过程8个~10个周期,最后在800℃下烧结,保温1h,得到粒径为50nm~100nm左右的多孔纳米薄膜.采用自制系统检测β-Ga2O3薄膜的氧敏性能,结果表明Fe掺杂的氧化镓薄膜材料,在400℃~800℃范围内,在理论空燃比附近,电阻突变幅度大于2个数量级,具有较高的灵敏度. 相似文献
89.
为了研究压铸模与铝合金金属间化合物的形成与分解过程,进行了热浸铝试验.试验结果表明金属间化合物的形成与分解是一个连续不断的循环过程,两者之间的相互关系导致了钢基的失重以及体积的减少. 相似文献
90.
CdZnTeCrystalGrowthbyVerticalGradientFreezingMethodHouQingrun;WangJinyi;DengJincheng;DuBing,(侯清润)(王金义)(邓金诚)(杜冰);LiMeirongandC... 相似文献