Structure−Activity Relationships of Cinnamate Ester Analogues as Potent Antiprotozoal Agents

Protozoal infections are still a global health problem, threatening the lives of millions of people around the world, mainly in impoverished tropical and sub-tropical regions. Thus, in view of the lack of efficient therapies and increasing resistances against existing drugs, this study describes the antiprotozoal potential of synthetic cinnamate ester analogues and their structure-activity relationships. In general, Leishmania donovani and Trypanosoma brucei were quite susceptible to the compounds in a structure-dependent manner. Detailed analysis revealed a key role of the substitution pattern on the aromatic ring and a marked effect of the side chain on the activity against these two parasites. The high antileishmanial potency and remarkable selectivity of the nitro-aromatic derivatives suggested them as promising candidates for further studies. On the other hand, the high in vitro potency of catechol-type compounds against T. brucei could not be extrapolated to an in vivo mouse model.     

Tuning of ferrimagnetic nature and hyperfine interaction of Ni2+ doped cobalt ferrite nanoparticles for power transformer applications

Ferrites may contain single domain particles which gets converted into super-paramagnetic state near critical size. To explore the existence of these characteristic feature of ferrites, we have performed magnetization(M-H loop) and Mössbauer spectroscopic studies of Ni²⁺ substitution effect in Co_1-xNi_xFe₂O₄ (where x?=?0, 0.25, 0.5, 0.75 and 1) nanoparticles were fabricated by solution combustion route using mixture of carbamide and glucose as fuels for the first time. As prepared samples exhibit spinel cubic structure with lattice parameters which decreases linearly with increase in Ni²⁺ concentration. The M-H loops reveals that saturation magnetization(M_s), coercive field(H_c) remanence magnetization(M_r) and magnetron number(η_B) decreases significantly with increasing Ni²⁺ substitution. The variation of saturation magnetization has been explained on the basis of Neel's molecular field theory. The coercive field(H_c) is found strongly dependent on the concentration of Ni²⁺ and decrease of coercivity suggests that the particles have single domain and exhibits superparamagnetic behavior. The Mössbauer spectroscopy shows two ferrimagnetically relaxed Zeeman sextets distribution at room temperature. The dependence of Mössbauer parameters such as isomer shift, quadru pole splitting, line width and hyperfine magnetic field on Ni²⁺ concentration have been discussed. Hence our results suggest that synthesized materials are potential candidate for power transformer application.     

Electromechanical analytical model of shape memory alloy based tunable cantilevered piezoelectric energy harvester

International Journal of Mechanics and Materials in Design - The resonant frequency of electromechanical energy harvester should be tuned to ambient frequency so as to maximize the harvester power....     

Studying the Effect of Cobalt Doping on Optical and Magnetic Properties of Zinc Oxide Nanoparticles

Silicon - Nano-crystalline powders of Zn1−xCoxO with $\left (0.0\le x\le 0.07 \right )$ have been synthesized by sol-gel method. X-ray diffraction patterns of the prepared samples confirm the...     

Optimal weighed Holoentropy for video compression: an advanced HEVC

ABSTRACT

In recent times, the applications of multimedia are rising in a greedy mode and hence the amount of video transactions is also increasing exponentially. This has shouted great demands on effective models on video encoding and also for reducing the transmission channel congestion. This research work introduces a managing technique termed weighted encoding for High-Efficiency Video Coding (HEVC). HEVC, also termed as MPEG-H Part 2 and H.265 is a video compression standard that is widely utilized AVC (H.264 or MPEG-4 Part 10). When compared to AVC, HEVC grants double the ratio of data compression at a similar level of quality of the video or considerably enhanced video quality at a similar bit rate. This work intends to optimize the weight that adopted in HEVC for encoding. For this, this paper proposes a new Iterative based propagation update in the water wave Optimization Algorithm (IPU-WWO), which is the improved form of Water wave Optimization (WWO). The performance of proposed IPU-WWO is compared over other conventional methods like Artificial Bee Colony (ABC), Firefly (FF), Particle Swarm Optimization (PSO) and Genetic Algorithm (GA) with respect to Peak Signal to Noise Ratio (PSNR). By doing the encoding process, it minimizes the video size with perceptually better quality video or PSNR.     

Effective Excitation of Magnetoelectric Voltage Harmonics in a Ferromagnet–Piezoelectric Structure by Current Passing through the Magnetic Layer

Technical Physics Letters - The magnetoelectric (ME) effect in a planar amorphous ferromagnet–piezoelectric lead zirconate titanate (PZT) composite structure can be effectively excited by...