Benefits of the use of impairment constraint routing in optical networks

In transparent optical networks, the optical signal accumulates the effects of all physical impairments present along the path it traverses. The conventional selection of signal paths based on e.g. shortest path routing without considering the signal quality and its association with the physical impairments does not always provide the optimum solution in terms of network performance such as blocking and resource utilization. This paper proposes an impairment constraint based routing algorithm to achieve an optimal combination of physical and networking performance taking into account all physical linear impairments including noise, chromatic and polarization mode dispersion, crosstalk and filter concatenation effects in an integrated approach. The performance of a typical metropolitan area network is examined and the improvement achieved when using the proposed approach compared to the conventional shortest path routing is demonstrated.     

Controlled Drug Release and Chemotherapy Response in a Novel Acoustofluidic 3D Tumor Platform

Overcoming transport barriers to delivery of therapeutic agents in tumors remains a major challenge. Focused ultrasound (FUS), in combination with modern nanomedicine drug formulations, offers the ability to maximize drug transport to tumor tissue while minimizing toxicity to normal tissue. This potential remains unfulfilled due to the limitations of current approaches in accurately assessing and quantifying how FUS modulates drug transport in solid tumors. A novel acoustofluidic platform is developed by integrating a physiologically relevant 3D microfluidic device and a FUS system with a closed‐loop controller to study drug transport and assess the response of cancer cells to chemotherapy in real time using live cell microscopy. FUS‐induced heating triggers local release of the chemotherapeutic agent doxorubicin from a liposomal carrier and results in higher cellular drug uptake in the FUS focal region. This differential drug uptake induces locally confined DNA damage and glioblastoma cell death in the 3D environment. The capabilities of acoustofluidics for accurate control of drug release and monitoring of localized cell response are demonstrated in a 3D in vitro tumor mode. This has important implications for developing novel strategies to deliver therapeutic agents directly to the tumor tissue while sparing healthy tissue.     

Efficient Coordination Mechanisms for Unrelated Machine Scheduling

We present three new coordination mechanisms for scheduling n selfish jobs on m unrelated machines. A coordination mechanism aims to mitigate the impact of selfishness of jobs on the efficiency of schedules by defining a local scheduling policy on each machine. The scheduling policies induce a game among the jobs and each job prefers to be scheduled on a machine so that its completion time is minimum given the assignments of the other jobs. We consider the maximum completion time among all jobs as the measure of the efficiency of schedules. The approximation ratio of a coordination mechanism quantifies the efficiency of pure Nash equilibria (price of anarchy) of the induced game. Our mechanisms are deterministic, local, and preemptive in the sense that the scheduling policy does not necessarily process the jobs in an uninterrupted way and may introduce some idle time. Our first coordination mechanism has approximation ratio Θ(logm) and always guarantees that the induced game has pure Nash equilibria to which the system converges in at most n rounds. This result improves a bound of O(log² m) due to Azar, Jain, and Mirrokni and, similarly to their mechanism, our mechanism uses a global ordering of the jobs according to their distinct IDs. Next we study the intriguing scenario where jobs are anonymous, i.e., they have no IDs. In this case, coordination mechanisms can only distinguish between jobs that have different load characteristics. Our second mechanism handles anonymous jobs and has approximation ratio $O(\frac{\log m}{\log\log m})$ although the game induced is not a potential game and, hence, the existence of pure Nash equilibria is not guaranteed by potential function arguments. However, it provides evidence that the known lower bounds for non-preemptive coordination mechanisms could be beaten using preemptive scheduling policies. Our third coordination mechanism also handles anonymous jobs and has a nice “cost-revealing” potential function. We use this potential function in order, not only to prove the existence of equilibria, but also to upper-bound the price of stability of the induced game by O(logm) and the price of anarchy by O(log² m). Our third coordination mechanism is the first that handles anonymous jobs and simultaneously guarantees that the induced game is a potential game and has bounded price of anarchy. In order to obtain the above bounds, our coordination mechanisms use m as a parameter. Slight variations of these mechanisms in which this information is not necessary achieve approximation ratios of O(m ^? ), for any constant ?>0.     

A PATH PLANNING METHOD BASED ON CELLULAR AUTOMATA FOR COOPERATIVE ROBOTS

A Cellular Automaton-based technique suitable for solving the path planning problem in a distributed robot team is outlined. Real-time path planning is a challenging task that has many applications in the fields of artificial intelligence, moving robots, virtual reality, and agent behavior simulation. The problem refers to finding a collision-free path for autonomous robots between two specified positions in a configuration area. The complexity of the problem increases in systems of multiple robots. More specifically, some distance should be covered by each robot in an unknown environment, avoiding obstacles found on its route to the destination. On the other hand, all robots must adjust their actions in order to keep their initial team formation immutable. Two different formations were tested in order to study the efficiency and the flexibility of the proposed method. Using different formations, the proposed technique could find applications to image processing tasks, swarm intelligence, etc. Furthermore, the presented Cellular Automaton (CA) method was implemented and tested in a real system using three autonomous mobile minirobots called E-pucks. Experimental results indicate that accurate collision-free paths could be created with low computational cost. Additionally, cooperation tasks could be achieved using minimal hardware resources, even in systems with low-cost robots.     

On stochasticity and turbulence in the federal funds market

This paper uses various tests from statistics and dynamical systems theory to support stochastic models to explain the behaviour of the federal funds rate. In particular, a fractional Brownian motion is supported by the power spectrum of the series, the structure function test and the Hurst test. A coloured noise model is supported by the signal differentiation test and the space-time separation test. Evidence against the turbulent behaviour hypothesis is also provided.     

Optical properties of aerosol over a South European urban environment

Aerosol optical depths (AODs) and single scattering albedos (SSAs) were derived from in situ aircraft measurements of scattering and absorption coefficients at 550 nm. These values were compared to the AODs and SSAs derived from the sun photometer (CIMEL) data of the Aerosol Robotic Network (AERONET) site, in Thessaloniki, Greece, between 18 and 21 July 2006. The aircraft-obtained AODs were lower than the corresponding columnar values. However, aircraft SSAs were found to be in good agreement with the columnar values retrieved from the CIMEL. Aircraft aerosol size distributions measured by means of an optical particle counter (OPC) were also in good agreement with the respective distributions derived from the AERONET site. Filter samples were collected on board the aircraft at different altitudes, to provide detailed information on the chemical composition of tropospheric aerosol. The concentrations of identified chemical species were used to calculate particle refractive indices (RIs) for comparison with the AERONET calculated values.     

The influence of alteration on the engineering properties of dolerites: The examples from the Pindos and Vourinos ophiolites (northern Greece)

The influence of alteration on the physico-mechanical properties of dolerites from the Pindos and Vourinos ophiolites, northern Greece, is investigated. Quantitative petrographic analysis shows that the samples display various percentages of secondary minerals. Two new micropetrographic indices are calculated from the results of petrographic modal analysis for the engineering assessment of dolerites: the micropetrographic strength index I_ps and the replacement index I_rep. The samples are also tested to determine water absorption, apparent density, total porosity, sand equivalent, uniaxial compressive strength, Los Angeles abrasion value, aggregate impact value, aggregate abrasion value and polished stone value. The influence of alteration on the rock quality and especially the relationships between the proposed micropetrographic indices and the engineering parameters are determined using regression analysis and the derived equations were verified by the t-test and the F-test. The relationships between the I_ps and I_rep indices and the engineering properties show that alteration products generally result in mechanically weaker rocks. However, the results of the physico-mechanical tests indicate that dolerites retain their strength and durability due to the low proportions of soft minerals and microcracks, along with the preservation of their igneous textures. The polishing resistance is the only engineering parameter that is positively affected by alteration processes, as expressed by the I_ps index. Particularly, the replacement of the primary mafic minerals by secondary minerals, expressed by the I_rep index, can enhance the polishing resistance of dolerites when used in the wearing surface of a road. The results also indicate strong positive correlations between the chlorite content and the water absorption and total porosity values.     

Amplification Effects of Soil Stratification on Ground Stress Waves

An analytical model is presented for the prediction of the amplification of compressional and shear waves produced by an explosion, or any other shock impact on the surface of a stratified soil deposit. This amplification is caused by multiple reflections of waves between the ground surface and an underlying parallel soil layer possessing different density and seismic velocity. The model developed may be easily applied for the protection of both buried and aboveground structures with the aid of suitable diagrams prepared in this work, which give, in a simple way, the enhancement factors by which particle velocities of direct waves should be multiplied to estimate the resultant particle velocities. The soil parameters that are taken into account in the analytical model and its simplified graphical solution are density, attenuation factor, and compressional- and shear-wave propagation velocities for the first two soil layers. Other parameters encountered are depth of the top soil layer, depth of burial of the structure, horizontal distance of the structure from the source, and trinitrotoluene equivalent of the source. The cube root scaling is considered for the attenuation of waves in soil with distance.     

On the properties of an additive increase rate accelerator

We propose AIRA, an Additive Increase Rate Accelerator. AIRA extends AIMD functionality towards adaptive increase rates, depending on the level of network contention and bandwidth availability. In this context, acceleration grows when resource availability is detected by goodput/throughput measurements and slows down when increased throughput does not translate into increased goodput as well. Thus, the gap between throughput and goodput determines the behavior of the rate accelerator.We study the properties of the extended model and propose, based on analysis and simulation, appropriate rate decrease and increase rules. Furthermore, we study conditional rules to guarantee operational success even in the presence of symptomatic, extra-ordinary events. We show that analytical rules can be derived for accelerating, either positively or negatively, the increase rate of AIMD in accordance with network dynamics. Indeed, we find that the “blind”, fixed Additive Increase rule can become an obstacle for the performance of TCP, especially when contention increases. Instead, sophisticated, contention-aware additive increase rates may preserve system stability and reduce retransmission effort, without reducing the goodput performance of TCP.     

Pre-treatment and ethanol fermentation potential of olive pulp at different dry matter concentrations

Renewable energy sources have received increased interest from the international community with biomass being one of the oldest and the most promising ones. In the concept of exploitation of agro-industrial residues, the present study investigates the pre-treatment and ethanol fermentation potential of the olive pulp, which is the semi solid residue generated from the two-phase processing of the olives for olive oil production. Wet oxidation and enzymatic hydrolysis have been applied aiming at the enhancement of carbohydrates' bioavailability. Different concentrations of enzymes and enzymatic durations have been tested. Both wet oxidation and enzymic treatment were evaluated based on the ethanol obtained in a subsequent fermentation step by Saccharomyces cerevisiae and Thermoanaerobacter mathranii. It was found that a four-day hydrolysis time was adequate for a satisfactory release of glucose and xylose. The combination of wet oxidation and enzymatic hydrolysis resulted in the glucose and xylose concentration increase of 138 and 444%, respectively, compared to 33 and 15% with only enzymes added. However, the highest ethanol production was obtained when only enzymic pre-treatment was applied, implying that wet oxidation is not a recommended pre-treatment process for olive pulp at the conditions tested. It was also showed that increased dry matter concentration did not have a negative effect on the release of sugars, indicating that the cellulose and xylan content of the olive pulp is relatively easily available. The results of the experiments in batch processes clearly emphasize that the simultaneous saccharification and fermentation (SSF) mode is advantageous in comparison with the separate hydrolysis and fermentation (SHF) mode concerning process contamination.