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61.
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Z Ma S Ramanadham K Kempe Z Hu J Ladenson J Turk 《Canadian Metallurgical Quarterly》1996,1308(2):151-163
We prepared polymers having a phospholipid polar group, poly [omega-methacryloyloxyalkyl phosphorylcholine (MAPC)-co-n-butyl methacrylate(BMA)], as new biomedical materials and evaluated their blood compatibility with attention to protein adsorption and platelet adhesion. The total amount of proteins adsorbed on the polymer surface from human plasma was determined, and the distribution of adsorbed proteins on the plasma-contacting surface was analyzed. The amount of proteins adsorbed on every poly (MAPC-co-BMA) was small compared with that observed on polymers without the phospholipid polar group. However, there was no significant difference in the amount of adsorbed proteins on the poly(MAPC-co-BMA) even when the methylene chain length between the phospholipid polar group and the backbone in the MAPC moiety was altered. Platelet adhesion on the polymer surface from a platelet suspension in a buffered solution was evaluated with and without plasma treatment on the surface. When a rabbit platelet suspension was brought into contact with the poly(BMA) surface after treatment with plasma, many platelets adhered and aggregated. However, a reduced amount of platelet adhered on the poly(BMA) was found in the case of direct contact with the platelet suspension. On the other hand, the poly(MAPC-co-BMA)s could inhibit platelet adhesion under both conditions. Based on these results, it can be concluded that the proteins adsorbed on the surface play an important role in determining the platelet adhesion and suppression of the protein adsorption on the surface, which is one of the most significant ways of inhibiting platelet adhesion. 相似文献
64.
Q Hu M Trevisan Y Xu W Dong SA Berger SD Lyman MD Minden 《Canadian Metallurgical Quarterly》1995,95(6):2530-2538
The growth of human leukemic cells in culture and in vivo is dependent upon the presence of hematopoietic growth factors. Most populations of human leukemic acute myeloblastic leukemia (AML) cells express c-Kit on their surface and respond to Kit ligand (KL) in culture. To determine if this interaction was of potential significance in vivo we used a mouse model system. 32D cells, a murine IL-3-dependent myeloid cell line, were rendered KL responsive by transfection of the murine c-Kit. After injection of 32D or 32D-Kit cells into syngeneic hosts, animals bearing 32D-Kit cells, but not 32D cells, became moribund and were killed. These animals had circulating leukemic blast cells, infiltration of bone marrow, spleen, brain, liver, lung, and kidney. Cells recovered from some of the animals continued to be dependent upon IL-3 or KL for growth while in other cases the cells were factor independent. This model illustrates that the constitutive expression of c-Kit enhances the leukemic potential of 32D cells. The model will be useful for studying the progression of leukemia in vivo and testing whether interruption of the interaction of Kit and KL can affect the growth of leukemic cells. 相似文献
65.
Voigt线型及其精确快速算法 总被引:1,自引:1,他引:0
通过把上半复平面分为4个区,并在每一区利用不同近似,建立了一种精确快速计算Voigt函数、修正的Voigt函数和Voigt函数偏导数的算法,其最大相对误差小于5×10-4.该算法是Line-by-Line大气透过率/辐射强度计算及其相关应用的有效算法. 相似文献
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Sha Lu Yong Hu O'Hara M. Bogy D.B. Singh Bhatia C. Yiao-Tee Hsia 《IEEE transactions on magnetics》1996,32(1):103-109
Three sub-25 nm fly height sliders are presented for near contact recording. The designs are geared towards the goal of achieving 10 Gb/in 2 areal density. The optimization procedure presented shows promise for facilitating achievement of this goal. The dynamic simulations show the stability of these designs when disturbed from their steady state conditions 相似文献
69.
利用钽不溶于酸的性质与稀土分离,用焦硫酸钾熔融,酒石酸浸取,制得被测溶液,采用ICP-AES测定其中钽量,结果令人满意。 相似文献
70.
ICA是一种含有中间件的网络软件体系结构,旨在以结构进化取得功能突破,据以全面支持来自用户的以及来自系统的各种应用需要。ICA的出台,表明国际上已建立起一种未来网定位新理念。ICA所代表的“信息通信”领域内的网络软件结构进化,立足于把未来网规范为三层结构,即“应用(Application)层”、“中间件(Middleware)层”和“基础(Baseware)层”。ICA的出现,对我国谋求新崛起是大好机遇,这不仅可以直接振兴我国网络软件产业,更可激励我国在新一轮的网络进化的进程中力争跻身“领潮国”的行列。“ICA融合了各种最新信息技术的长处”。ICA结构进化,标志着当今网络进化的时代特征。推进和实现基于ICA的未来网,有着较佳的可行性。 相似文献