Methods for Conceptual Thermal Design

This article describes three generic models and application methods that can be used to analyze temperature development in an electronic product during conceptual design. The models are based on generally known heat transfer and resistor–capacitor network theory and are theoretically and numerically approximated. The result is three easy-to-use tools for conceptual thermal design. Application of the models in design practice has been assessed using a usability experiment and several in-depth interviews with industrial design engineers from the field.     

The Multi-Mode Resource-Constrained Multi-Project Scheduling Problem

Scheduling projects is a difficult and time consuming process, and has far-reaching implications for any organization’s operations. By generalizing various aspects of project scheduling, decision makers are enabled to capture reality and act accordingly. In the context of the MISTA 2013 conference, the first MISTA challenge, organized by the authors, introduced such a general problem model: the Multi-Mode Resource-Constrained Multi-Project Scheduling Problem (MRCMPSP). The present paper reports on the competition and provides a discussion on its results. Furthermore, it provides an analysis of the submitted algorithms, and a study of their common elements. By making all benchmark datasets and results publicly available, further research on the MRCMPSP is stimulated.     

Partitioned simulation of the interaction between an elastic structure and free surface flow

Currently, the interaction between free surface flow and an elastic structure is simulated with monolithic codes which calculate the deformation of the structure and the liquid–gas flow simultaneously. In this work, this interaction is calculated in a partitioned way with a separate flow solver and a separate structural solver using the interface quasi-Newton algorithm with approximation for the inverse of the Jacobian from a least-squares model (IQN-ILS). The interaction between an elastic beam and a sloshing liquid in a rolling tank is calculated and the results agree well with experimental data. Subsequently, the impact of both a rigid cylinder and a flexible composite cylinder on a water surface is simulated to assess the effect of slamming on the components of certain wave-energy converters. The impact pressure on the bottom of the rigid cylinder is nearly twice as high as on the flexible cylinder, which emphasizes the need for fluid–structure interaction calculations in the design process of these wave-energy converters. For both the rolling tank simulations and the impact simulations, grid refinement is performed and the IQN-ILS algorithm requires the same number of iterations on each grid. The simulations on the coarse grid are also executed using Gauss-Seidel coupling iterations with Aitken relaxation which requires significantly more coupling iterations per time step.     

Confrontations with aggression and mental health problems in police officers: The role of organizational stressors, life-events and previous mental health problems.

The extent to which the frequency of facing aggression incidents is associated with mental health problems among police officers when organizational stressors, life-events, and previous mental health problems are taken into account is unclear. To elucidate this data from a longitudinal study of police officers was analyzed (N = 473). Mental health problems (MHPs) are here defined as severe anxiety, depression, hostility, burnout symptoms, and/or sleeping problems according the SCL-90–R and MBI. All MHPs were assessed at baseline and 27 months later. Logistic regression showed that serious threat was statistically significant associated with MHPs at follow-up among officers without MHPs at baseline, but not among those with MHPs at baseline. However, stepwise logistic regression showed that serious threat and/or physical aggression were not independently associated with MHPs at follow-up. Organizational stressors, that is, problems with colleagues were independent predictors in all analyses. Among the total study sample, previous MHPs were the strongest independent predictors. These findings suggest superiors should attend to the mental health, organizational stressors and life-events of their officers regularly and not only following critical incidents at work. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Quantitative imaging through a spectrograph. 1. Principles and theory

Laser-based optical diagnostics, such as planar laser-induced fluorescence and, especially, Raman imaging, often require selective spectral filtering. We advocate the use of an imaging spectrograph with a broad entrance slit as a spectral filter for two-dimensional imaging. A spectrograph in this mode of operation produces output that is a convolution of the spatial and spectral information that is present in the incident light. We describe an analytical deconvolution procedure, based on Bayesian statistics, that retrieves the spatial information while it avoids excessive noise blowup. The method permits direct imaging through a spectrograph, even under broadband illumination. We introduce the formalism and discuss the underlying assumptions. The performance of the procedure is demonstrated on an artificial but pathological example. In a companion paper [Appl. Opt. 43, 5682-5690 (2004)] the method is applied to the practical case of fuel equivalence ratio Raman imaging in a combustible methane-air mixture.     

Analysis of DNA Replication by Optical Mapping in Nanochannels

DNA replication is essential to maintain genome integrity in S phase of the cell division cycle. Accumulation of stalled replication forks is a major source of genetic instability, and likely constitutes a key driver of tumorigenesis. The mechanisms of regulation of replication fork progression have therefore been extensively investigated, in particular with DNA combing, an optical mapping technique that allows the stretching of single molecules and the mapping of active region for DNA synthesis by fluorescence microscopy. DNA linearization in nanochannels has been successfully used to probe genomic information patterns along single chromosomes, and has been proposed to be a competitive alternative to DNA combing. Yet this conjecture remains to be confirmed experimentally. Here, two complementary techniques are established to detect the genomic distribution of tracks of newly synthesized DNA in human cells by optical mapping in nanochannels. Their respective advantages and limitations are compared, and applied them to detect deregulations of the replication program induced by the antitumor drug hydroxyurea. The developments here thus broaden the field of applications accessible to nanofluidic technologies, and can be used in the future as part for molecular diagnostics in the context of high throughput cancer drug screening.     

Properties of poly(butylene terephthatlate) polymerized from cyclic oligomers and its composites

The high viscosity of thermoplastic matrices hampers fiber impregnation. This problem can be overcome by using low viscous polymeric precursors such as cyclic butylene terephthalate (CBT^® resins), which polymerize to form a thermoplastic matrix. This allows thermoset production techniques, like resin transfer molding (RTM), to be used for the production of textile reinforced thermoplastics. Due to the processing route and more specifically the time-temperature profile, inherent to the RTM process, the crystallites of the matrix consist out of well-defined, thick and well-oriented crystal lamellae. Together with a high overall degree of crystallinity and a low density of tie molecules, these large and perfect crystals cause polymer brittleness. Matrix brittleness lowers the transverse strength of unidirectional composites to below the matrix strength, but leaves the mechanical properties in the fiber direction unaffected. Although not a valid option for the RTM production route, crystallization from a truly random melt and at a sufficiently high cooling rate would substantially improve the ductility.     

Thermosensitive Molecular,Colloidal, and Bulk Interactions Using a Simple Surfactant

Efficient use of (nano)particle self‐assembly for creating nanostructured materials requires sensitive control over the interactions between building blocks. Here, a very simple method for rendering the interactions between almost any hydrophobic nano‐ and microparticles thermoswitchable is described and this attraction is characterized using colloid probe atomic force microscopy (CP‐AFM). In a single‐step synthesis, a thermoresponsive surfactant is prepared that through physical adsorption generates a thermosensitive brush on hydrophobic surfaces. These surface layers can reversibly trigger gelation and crystallization of nano‐ and microparticles, and at the same time can be used to destabilize emulsions on demand. The method requires no chemical surface modification yet is universal, reproducible, and fully reversible.