A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals.

Objective: To evaluate cognitive-behavioral therapy to enhance medication adherence and reduce depression (CBT-AD) in individuals with HIV. Design: A two arm, randomized, controlled, cross-over trial comparing CBT-AD to enhanced treatment as usual only (ETAU). ETAU, which both groups received, included a single-session intervention for adherence and a letter to the patient's provider documenting her or his continued depression. The intervention group also received 10 to 12 sessions of CBT-AD. Main Outcome Measures: Adherence to antiretroviral therapy as assessed by Medication Event Monitoring Systems (MEMs) and depression as assessed by blinded structured evaluation. Results: At the acute outcome assessment (3-months), those who received CBT-AD evidenced significantly greater improvements in medication adherence and depression relative to the comparison group. Those who were originally assigned to the comparison group who chose to cross over to CBT-AD showed similar improvements in both depression and adherence outcomes. Treatment gains for those in the intervention group were generally maintained at 6- and 12-month follow-up assessments. By the end of the follow-up period, those originally assigned CBT-AD demonstrated improvements in plasma HIV RNA concentrations, though these differences did not emerge before the cross-over, and hence there were not between-groups differences. Conclusions: CBT-AD is a potentially efficacious approach for individuals with HIV struggling with depression and adherence. Replication and extension in larger efficacy trials are needed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A continual improvement framework with integration of CMMI and six‐sigma model for auto industry

During the recent years, the major driving forces of customer preference, vehicle safety, environmental protection, and flat demand for new cars led to a proliferation of car models and associated price reduction in the auto supply chain. To react to the complex and competitive environment, auto suppliers are urgent to conduct continual improvement (CI) in an effective and systematic way. Thus, this paper presents a framework for CI. The Integrated Development System is proposed to integrate both capability maturity model integration and six‐sigma approach. By implementing the framework, an automaker can establish a solid process‐based management system, identify critical processes, and optimize these processes. For demonstrating the application of this framework, a case study is presented and the result shows that all expected processes' performance targets are achieved, which has dramatically improved by 70% compared with the past records. Apparently, the proposed framework would act as a useful reference to improve an organization's process maturity. Copyright © 2008 John Wiley & Sons, Ltd.     

英国公司QuantaSol打破太阳能电池记录

帝国理工学院(Imperial Collage)剥离出来的QuantaSol声称,他们已经打破了单结太阳能电池的世界记录。当曝露在500倍聚光的条件下,应力平衡的量子阱太阳能电池的转换效率记录为28.3%。     

Configuration management and security

Proper configuration management is vital for host and network security. We outline the problems, especially for large-scale environments, and discuss the security aspects of a number of different configuration scenarios, including security appliances (e.g., firewalls), desktop and server computers, and PDAs. We conclude by discussing research challenges.     

Steady-state and transient ampacity of bus bar

This paper presents a thermal model that can be used to calculate both the steady-state and transient electrical current carrying capacity (ampacity) of a power system busbar. Using a thermal model, a computer program has been formulated that can calculate the ampacity of busbar for any time-varying current and any variation in environmental conditions. Relations for the convection heat transfer coefficient for busbars with circular, rectangular and angular cross-sections are presented. The steady state values for ampacity predicted by the program are compared to accepted values. The transient capabilities of the program are illustrated by calculating the variation in busbar temperature when it is subjected to a step change in current. The predicted temperature histories of typical bus designs are compared to temperatures measured in the laboratory using thermocouples attached to the bus material     

US EPA's acute reference exposure methodology for acute inhalation exposures

The US Environmental Protection Agency (EPA) National Center for Environmental Assessment is engaged in the development of a methodology for Agency use to perform risk assessments for non-cancer effects due to acute inhalation exposures. The methodology will provide general guidance for deriving chemical-specific acute exposure benchmarks called acute reference exposures (AREs). Chemical-specific AREs are analogous to reference concentra tions (RfCs) for chronic non-cancer effects and will be incorporated in chemical-specific files in the US EPA's Integrated Risk Information System (IRIS) as they are developed and reviewed. AREs will have wide applicability in assessing the potential health risks of accidental and routine acute releases of chemicals to the environment. The proposed methodology for ARE development provides a framework for choosing an optimal derivation approach, depending on the type of data available, from the no-observed-adverse-effect level (NOAEL), benchmark concentration (BMC), or categorical regression approaches. Uncertainty factors are applied to the point of departure, determined by one of the recommended approaches, to derive the ARE. Due to the capability to use more exposure-response information than the NOAEL approach allows, exposure-response analyses such as BMC and categorical regression are favored as methods to develop the point of departure when the available database will support such analyses. The NOAEL approach is suitable when the data are insufficient to support exposure-response modeling. Applications of the proposed ARE methodology are illustrated by the derivation of example AREs for hydrogen sulfide and hexachlorocyclopentadiene, which showcase the categorical regression and NOAEL approaches, respectively. In addition, a recent review of the proposed ARE methodology by the US EPA Risk Assessment Forum is discussed.     

The perceived urgency of speech warnings: semantics versus acoustics

The relationship between the semantics of words and the acoustics of the way they are spoken is explored. Actors spoke warning signal words in an urgent, nonurgent and monotone style, and participants rated the urgency of the words. Results showed effects for signal word and style of presentation. Acoustic analysis showed that the urgent words were spoken at higher frequency with a broader pitch range and were louder than the nonurgent or monotone words. These acoustic differences were used to synthesize artificial versions of signal words in urgent and nonurgent formats. The urgent words were rated as more urgent than the nonurgent words, a finding attributable to their differing acoustics. Within each speaking style the words were acoustically the same, yet effects for signal word were found, suggesting that semantics is also important in urgency perception. This research has implications for the design and implementation of speech warning systems, particularly those in which urgency mapping is required.     

Personality traits, perceived risk, and risk-reduction behaviors: A further study of smoking and radon.

Personality traits and risk perceptions were examined as predictors of changes in smoking behavior. Participants (N = 697) were part of a randomized controlled trial of interventions to reduce exposure to the combined hazard of radon and cigarette smoke. Participants with higher perceived risk at baseline for the combination of smoking and radon were more likely to have a more restrictive household smoking ban in place at 12-month follow-up (p p p     

Modeling relations between hassles and internalizing and externalizing symptoms in adolescents: A four-year prospective study.

This study examined the relations between hassles and internalizing and externalizing symptoms across 4 years in adolescents who varied with regard to their risk for psychopathology. The sample comprised 240 adolescents assessed in 6th, 7th, 8th, and 9th grades regarding their level of peer and academic hassles and internalizing and externalizing symptoms. Structural equation modeling was used to construct latent variables of hassles and internalizing and externalizing syndromes. Results varied by informant about the teens' symptoms. For adolescent report, the stress exposure model fit the data best for internalizing syndromes; that is, higher levels of stressors predicted significantly higher levels of self-reported symptoms 1 year later. For mother report of adolescents' symptoms, the stress generation model fit the data best for both internalizing and externalizing syndromes; that is, higher levels of adolescents' internalizing and externalizing symptoms, as reported by their mothers, significantly predicted higher levels of hassles 1 year later. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Reconciling user and project manager perceptions of IT project risk: a Delphi study1

Abstract. In an increasingly dynamic business environment characterized by fast cycle times, shifting markets and unstable technology, a business organization’s survival hinges on its ability to align IT capabilities with business goals. To facilitate the successful introduction of new IT applications, issues of project risk must be addressed, and the expectations of multiple stakeholders must be managed appropriately. To the extent that users and developers may harbour different perceptions regarding project risk, areas of conflict may arise. By understanding the differences in how users and project managers perceive the risks, insights can be gained that may help to ensure the successful delivery of systems. Prior research has focused on the project manager’s perspective of IT project risk. This paper explores the issue of IT project risk from the user perspective and compares it with risk perceptions of project managers. A Delphi study reveals that these two stakeholder groups have different perceptions of risk factors. Through comparison with a previous study on project manager risk perceptions, zones of concordance and discordance that must be reconciled are identified.