Integration of radar and Landsat-derived foliage projected cover for woody regrowth mapping, Queensland, Australia

In Queensland, Australia, forest areas are discriminated from non-forest by applying a threshold (∼ 12%) to Landsat-derived Foliage Projected Cover (FPC) layers (equating to ∼ 20% canopy cover), which are produced routinely for the State. However, separation of woody regrowth following agricultural clearing cannot be undertaken with confidence, and is therefore not mapped routinely by State Agencies. Using fully polarimetric C-, L- and P-band NASA AIRSAR and Landsat FPC data for forests and agricultural land near Injune, central Queensland, we corroborate that woody regrowth dominated by Brigalow (Acacia harpophylla) cannot be discriminated using either FPC or indeed C-band data alone, because the rapid attainment of a canopy cover leads to similarities in both reflectance and backscatter with remnant forest. We also show that regrowth cannot be discriminated from non-forest areas using either L-band or P-band data alone. However, mapping can be achieved by thresholding and intersecting these layers, as regrowth is unique in supporting both a high FPC (> ∼ 12%) and C-band SAR backscatter (> ~ − 18 dB at HV polarisation) and low L-band and P-band SAR backscatter (e.g. < =∼ 14 dB at L-band HH polarisation). To provide a theoretical explanation, a wave scattering model based on that of Durden et al. [Durden, S.L., Van Zyl, J.J. & Zebker, H.A. (1989). Modelling and observation of radar polarization signature of forested areas. IEEE Trans. Geoscience and Remote Sensing, 27, 290-301.] was used to demonstrate that volume scattering from leaves and small branches in the upper canopy leads to increases in C-band backscattering (particularly HV polarisations) from regrowth, which increases proportionally with FPC. By contrast, low L-band and P-band backscatter occurs because of the lack of double bounce interactions at co-polarisations (particularly HH) and volume scattering at HV polarisation from the stems and branches, respectively, when their dimensions are smaller than the wavelength. Regrowth maps generated by applying simple thresholds to both FPC and AIRSAR L-band data showed a very close correspondence with those mapped using same-date 2.5 m Hymap data and an average 73.7% overlap with those mapped through time-series comparison of Landsat-derived land cover classifications. Regrowth mapped using Landsat-derived FPC from 1995 and JER-1 SAR data from 1994-1995 also corresponded with areas identified within the time-series classification and true colour stereo photographs for the same period. The integration of Landsat FPC and L-band SAR data is therefore expected to facilitate regrowth mapping across Queensland and other regions of Australia, particularly as Japan's Advanced Land Observing System (ALOS) Phase Arrayed L-band SAR (PALSAR), to be launched in 2006, will observe at both L-band HH and HV polarisations.     

Using informal notes for sharing corporate technology know-how

Corporate and academic communities have focused a great deal of attention on formalized approaches for creating, capturing, and propagating knowledge. Far less attention has been paid to the informal mechanisms that individuals share and employ to help them navigate complex processes in order to ‘get things done.’ In this paper, we examine the creation, use, and content of informal documents for supporting users of an enterprise resource planning system in a Fortune 500 company. We contend that such notes, which are commonly used for supporting information systems-related work, are an overlooked source of knowledgeability about organizational practices. This study is a first but necessary step in analyzing the types of information that can be derived from informal notes so that organizations can more fully utilize this largely untapped resource.     

A histomorphological study in age related changes in the elastic fiber system of the basilar artery

The aim of the study was to quantify the distribution of elastic fibers within the wall of the basilar artery. Three age groups were studied: 1) 0-1 yr.; 2) 20-50 yr. 3) > 50 yr. A histomorphometrical study was undertaken using an estimation of the linear density of the components of the fibrous elastic tissue system: the full length in the proximal and distal segments of the basilar artery was evaluated. Our results showed that: The elastic tissue of the basilar artery is not evenly distributed throughout the tunica media. Compared to the 0 to 1-year age group, mature elastic, elauninic and oxytalan fibers decreased with age. In all age groups the linear density of the mature elastic fibers was more evident in the proximal than in the distal segment of the artery.     

3D Visualization for 2D GIS: an Analysis of the Users' Needs and a Review of Techniques*

Most of the existing geographical information systems (GIS) make limited use of algorithms for advanced computer graphics and visualization. One explanation is that few attempts are made to identify the visualization needs for different uses of GIS, and to couple such needs to the available algorithms. Another explanation is that most GIS are designed to handle two-dimensional (20) data with few obvious relationships to three-dimensional (30) visualization. In an attempt to provide a better understanding of the application of visualization in GIS, we propose a conceptual framework linking several aspects of the two fields. At the user-level, we link different uses of GIS to different categories of audience and presentation styles. At the level of implementation, we first propose different ways to create 3D data for visualization from 2D GIS data, and then we review algorithms and techniques for 3D visualization with respect to support of different presentation styles.     

Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year randomized double-blind study

OBJECTIVE: Obesity is an important risk factor for type 2 diabetes. Weight loss in patients with type 2 diabetes is associated with improved glycemic control and reduced cardiovascular disease risk factors, but weight loss is notably difficult to achieve and sustain with caloric restriction and exercise. The purpose of this study was to assess the impact of treatment with orlistat, a pancreatic lipase inhibitor, on weight loss, glycemic control, and serum lipid levels in obese patients with type 2 diabetes on sulfonylurea medications. RESEARCH DESIGN AND METHODS: In a multicenter 57-week randomized double-blind placebo-controlled study, 120 mg orlistat or placebo was administered orally three times a day with a mildly hypocaloric diet to 391 obese men and women with type 2 diabetes who were aged > 18 years, had a BMI of 28-40 kg/m2, and were clinically stable on oral sulfonylureas. Changes in body weight, glycemic control, lipid levels, and drug tolerability were measured. RESULTS: After 1 year of treatment, the orlistat group lost 6.2 +/- 0.45% (mean +/- SEM) of initial body weight vs. 4.3 +/- 0.49% in the placebo group (P < 0.001). Twice as many patients receiving orlistat (49 vs. 23%) lost > or = 5% of initial body weight (P < 0.001). Orlistat treatment plus diet compared with placebo plus diet was associated with significant improvement in glycemic control, as reflected in decreases in HbA1c (P < 0.001) and fasting plasma glucose (P < 0.001) and in dosage reductions of oral sulfonylurea medication (P < 0.01). Orlistat therapy also resulted in significantly greater improvements than placebo in several lipid parameters, namely, greater reductions in total cholesterol, (P < 0.001), LDL cholesterol (P < 0.001), triglycerides (P < 0.05), apolipoprotein B (P < 0.001), and the LDL-to-HDL cholesterol ratio (P < 0.001). Mild to moderate and transient gastrointestinal events were reported with orlistat therapy, although their association with study withdrawal was low. Fat-soluble vitamin levels generally remained within the reference range, and vitamin supplementation was required in only a few patients. CONCLUSIONS: Orlistat is an effective treatment modality in obese patients with type 2 diabetes with respect to clinically meaningful weight loss and maintenance of weight loss, improved glycemic control, and improved lipid profile.     

Least-squares moment matching reduction methods

It is shown how the two apparently different approaches to modelling reduction by least-squares time moment matching give identical results. This property also enables a clear understanding of how the method actually approximates the system. Computational savings are seen to be made by adopting the two-stage approach     

The activation of fibroblast growth factors (FGFs) by glycosaminoglycans: influence of the sulfation pattern on the biological activity of FGF-1

Six synthetic heparin-like oligosaccharides have been used to investigate the effect of the oligosaccharide sulfation pattern on the stimulation of acidic fibroblast growth factor (FGF-1) induced mitogenesis signaling and the biological significance of FGF-1 trans dimerization in the FGF-1 activation process. It has been found that some molecules with a sulfation pattern that does not contain the internal trisaccharide motif, which has been proposed for high affinity for FGF-1, stimulate FGF-1 more efficiently than those with the structure of the regular region of heparin. In contrast to regular region oligosaccharides, in which the sulfate groups are distributed on both sides of their helical three-dimensional structures, the molecules containing this particular sulfation pattern display the sulfate groups only on one side of the helix. These results and the fact that these oligosaccharides do not promote FGF-1 dimerization according to sedimentation-equilibrium analysis, confirm the importance of negative-charge distribution in the activation process and strongly suggest that FGF dimerization is not a general and absolute requirement for biological activity.