The semigroups of linearly realizable finite automata. I

Summary First the problem is solved how one can decide whether an arbitrary finite semigroup H is linearly A-realizable, i.e., whether there exists a linearly realizable finite automaton having a semigroup isomorphic to H. This leads to a question about the existence of certain generating subsets of H. The determination of these subsets is rather complicated in case H-HH=Ø and very simple in case H-HH#Ø. But in the first case we are able to clear up completely the structure of the semigroups which are linearly A-realizable: These are exactly the finite right groups which have maximal subgroups of the type described by Ecker in [4]. In the second case we get only necessary structure conditions. Among other things we shall see: If a semigroup H is linearly A-realizable one can define a congruence relation on it having the property, that H is isomorphic to a semigroup of a strongly connected and linearly realizable automaton iff the so-called index of H equals the index of H/. Developing these results about semigroups we obtain at the same time many structure theorems about linearly realizable automata.     

Identification of the female-produced sex pheromone of the scarab beetle,Hoplia equina

Hoplia equina LeConte (Coleoptera: Scarabaeidae: Melolonthinae) is a beetle pest of cranberry beds in Massachusetts. Larvae feed on the roots of the cranberry plant, reducing yield as well as vine density. The female sex pheromone was identified as 2-tetradecanone. There were eight compounds found in the airborne volatiles collected from females that elicited antennal responses from males. Of the eight compounds tested (nonanal, decanal, dodecanal, 2-dodecanone, 2-tridecanone, 2-tetradecanone, 2-pentadecanone, and 2-hexadecanone), 2-tetradecanone was the only one that attracted male beetles in the field. Combining any of the other seven antennally active compounds with 2-tetradecanone did not increase male capture.     

Inhibition of HeLa cell messenger RNA translation by 7-methylguanosine 5'-monophosphate

Translation of HeLa cell RNA containing poly(A) in a wheat germ cell-free system is markedly but incompletely inhibited by 7-methylguanosine 5'-monophosphate (m7G5'p). We have analyzed the translation products synthesized in the presence of different concentrations of m7G5'p and find that translation of all mRNAs is equally inhibited. To demonstrate the specificity of the inhibitor for RNAs with 5'-terminal m7G5' ppp... we show that specific translation products of satellite tobacco necrosis virus RNA, which does not have this 5' terminus, are synthesized in the presence of m7G5' p. Protein synthesis programmed by endogenous mRNA in a HeLa cell-free system is inhibited after a 10-min lag by m7G5' p. Other guanosine nucleotides without the 7-methyl group or with the phosphate in a different position are not inhibitor. We show that translation of all mRNAs is inhibited to a similar extent by m7G5'p in the HeLa cell-free system, by synthesizing 35S-labeled proteins in the presence of different inhibitory concentrations of this nucleotide and analyzing the translation products by electrophoresis and autoradiography. Translation of encephalomyocarditis virus RNA added to the HeLa cell-free system is not inhibited by m7"g5p; this viral RNA does not have this nucleotide at the 5' terminus. This indicates that m7G5'p specifically inhibits translation of mRNAs with the 5' terminus m7G5'ppp... and suggests that initiation of translation of picornavirus RNA may proceed via a mechanism different from that of cellular mRNAs.     

Selecting scientific excellence through committee peer review - A citation analysis of publications previously published to approval or rejection of post-doctoral research fellowship applicants

Summary We investigated committee peer review for awarding long-term fellowships to post-doctoral researchers as practiced by the Boehringer Ingelheim Fonds (B.I.F.) - a foundation for the promotion of basic research in biomedicine. Assessing the validity of selection decisions requires a generally accepted criterion for research impact. A widely used approach is to use citation counts as a proxy for the impact of scientific research. Therefore, a citation analysis for articles published previous to the applicants' approval or rejection for a B.I.F. fellowship was conducted. Based on our model estimation (negative binomial regression model), journal articles that had been published by applicants approved for a fellowship award (n = 64) prior to applying for the B.I.F. fellowship award can be expected to have 37% (straight counts of citations) and 49% (complete counts of citations) more citations than articles that had been published by rejected applicants (n = 333). Furthermore, comparison with international scientific reference values revealed (a) that articles published by successful and non-successful applicants are cited considerably more often than the “average” publication and (b) that excellent research performance can be expected more of successful than non-successful applicants. The findings confirm that the foundation is not only achieving its goal of selecting the best junior scientists for fellowship awards, but also successfully attracting highly talented young scientists to apply for B.I.F. fellowships.     

Complex system reliability modelling with Dynamic Object Oriented Bayesian Networks (DOOBN)

Nowadays, the complex manufacturing processes have to be dynamically modelled and controlled to optimise the diagnosis and the maintenance policies. This article presents a methodology that will help developing Dynamic Object Oriented Bayesian Networks (DOOBNs) to formalise such complex dynamic models. The goal is to have a general reliability evaluation of a manufacturing process, from its implementation to its operating phase. The added value of this formalisation methodology consists in using the a priori knowledge of both the system's functioning and malfunctioning. Networks are built on principles of adaptability and integrate uncertainties on the relationships between causes and effects. Thus, the purpose is to evaluate, in terms of reliability, the impact of several decisions on the maintenance of the system. This methodology has been tested, in an industrial context, to model the reliability of a water (immersion) heater system.     

Predicting change for individual psychotherapy clients on the basis of their nearest neighbors.

This study extended client-focused research by using the nearest neighbor (NN) approach, a client-specific sampling and prediction strategy derived from research on alpine avalanches. Psychotherapy clients (N = 203) seen in routine practice settings in the United Kingdom completed a battery of intake measures and then completed symptom intensity ratings before each session. Forecasts of each client's rate of change and session-by-session variability were computed on the basis of that client's NNs (n = 10-50 in different comparisons). Alternative forecasts used linear or log-linear slopes and were compared with an alternative prediction strategy. Results showed that the NN approach was superior to the alternative model in predicting rate of change, though the advantage was less clear for predicting variability. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Elemental dissolution study of Pu-bearing borosilicate glasses

Single-pass flow-through tests were conducted to study the effects of self-radiation damage from alpha decay on dissolution kinetics of three radiation-aged Pu-bearing (1 mass% PuO₂) borosilicate glasses over a pH interval of 9–12 at 80–88 °C. The chemical compositions of the glasses were identical except the ²³⁹Pu/²³⁸Pu isotopic ratio, which was varied to yield accumulated doses of 1.3 × 10¹⁶, 2.9 × 10¹⁷ and 2.6 × 10¹⁸ -decays/g at the time of testing. Release of Al, B, Cs, Na, Si and U to solution increased with increasing pH, whereas Ca, Pu and Sr were invariant over the pH interval. Average dissolution rates, based on B release, were identical within experimental uncertainty for all three glass compositions and increased from 0.17 ± 0.07 at pH(23 °C) 9 to 10.6 ± 2.7 (g/(m² d¹)) at pH(23 °C) 12. Release rates of Pu were 10²- to 10⁵-fold slower compared to all other elements and were not affected by isotopic composition, self-radiation damage sustained by the glass, or pH. These data demonstrate that self-radiation damage does not affect glass dissolution rates, despite exposure to internal radiation doses for >20 years.     

Adoption of electronic options trading at the ISE

US brokerage firms have shown strong interest in a new alternative for trading of equity options since the 26 May 2000 launch of the International Securities Exchange (ISE), an all-electronic trading platform. Although the collective impact of these adoption decisions led to a successful launch and a formidable competitor to the four established options markets in the US, major brokerage firms differ widely in their usage and adoption rates.