Schrifttumsberichte

Ohne Zusammenfassung     

Nutritional Calcium Supply Dependent Calcium Balance,Bone Calcification and Calcium Isotope Ratios in Rats

Serum calcium isotopes (δ^44/42Ca) have been suggested as a non-invasive and sensitive Ca balance marker. Quantitative δ^44/42Ca changes associated with Ca flux across body compartment barriers relative to the dietary Ca and the correlation of δ^44/42Ca_Serum with bone histology are unknown. We analyzed Ca and δ^44/42Ca by mass-spectrometry in rats after two weeks of standard-Ca-diet (0.5%) and after four subsequent weeks of standard- and of low-Ca-diet (0.25%). In animals on a low-Ca-diet net Ca gain was 61 ± 3% and femur Ca content 68 ± 41% of standard-Ca-diet, bone mineralized area per section area was 68 ± 15% compared to standard-Ca-diet. δ^44/42Ca was similar in the diets, and decreased in feces and urine and increased in serum in animals on low-Ca-diet. δ^44/42Ca_Bone was higher in animals on low-Ca-diet, lower in the diaphysis than the metaphysis and epiphysis, and unaffected by gender. Independent of diet, δ^44/42Ca_Bone was similar in the femora and ribs. At the time of sacrifice, δ^44/42Ca_Serum inversely correlated with intestinal Ca uptake and histological bone mineralization markers, but not with Ca content and bone mineral density by µCT. In conclusion, δ^44/42Ca_Bone was bone site specific, but mechanical stress and gender independent. Low-Ca-diet induced marked changes in feces, serum and urine δ^44/42Ca in growing rats. δ^44/42Ca_Serum inversely correlated with markers of bone mineralization.     

On enhanced non-linear free surface flow simulations with a hybrid LBM–VOF model

In this paper, we present extensions, extensive validations and applications of our previously published hybrid volume-of-fluid-based (VOF) model for the simulation of free-surface flow problems. For the solution of the flow field, the lattice Boltzmann method is used, where the free surface is represented by a VOF approach. The advection equation for the VOF fill level is discretized with a finite volume method, on the basis of a 3D Piecewise Linear Interface Reconstruction (PLIC) algorithm. The model is validated for several standard free surface benchmarks, such as breaking dam scenarios and a free falling jet. Finally, the hybrid algorithm is applied to the simulation of a wave breaking by overturning during shoaling, which is considered to be a demanding test case, especially for VOF solvers. In this case, the flow field is initialized early in the shoaling process with a solitary wave solution from inviscid, irrotational potential flow. The wave breaking process is then simulated with the 3D transient and turbulent LBM–VOF solver. All validation and benchmark tests confirm the accuracy of the proposed hybrid model.     

TIME'S ARROW IN PARTICLE PHYSICS

This article gives an introduction into the current understanding of time invariance and evidence of its violation in experimental particle physics. The connection between time invariance and other discrete symmetries, particularly, CP-invariance, is explained. The first experimental determination of CP-violation is explained, and recent experiments on CP-violation and on T-violation are discussed.     

Slip behaviour at cyclic pullout tests under transverse tension

In case of a reinforced concrete structure being exposed to bond stresses that transfer great forces, a relative displacement between reinforcing bar and concrete occurs. The slip is an important parameter in order to evaluate the quality of the bond concerning repeated pullout loads. A rapid slip increase is caused by bond weakening due to longitudinal cracks resulting from transverse tension. Within the bond area the slip is not uniformly distributed along the reinforcing bar. It is still unexplained how far fatigue and transverse tension affect the distribution. This paper focuses on the development of the slip curve under repeated loading and transverse tension. Results from cyclic pullout tests were applied and particularly the slip difference between the loaded and unloaded end of the pullout bar was investigated. It could be observed that both an increase in load cycles and transverse tension did not cause an appreciable change in slip difference.     

Modification of CaCO3 precipitation rates by water-soluble nacre proteins

Mineral growth in nacre and other CaCO₃-containing biominerals is controlled by biopolymers. Water-soluble proteins were extracted from nacre of the sea snail Haliotis laevigata by dissolving the mineral phase with 6% acetic acid. The influence of this protein mixture on CaCO₃ precipitation rates was investigated at different concentrations. A well-established assay for measuring the pH-value during CaCO₃ precipitation with and without protein additives was extended by calculating maximum precipitation rates from the pH-values. It could be shown that precipitation rates are greatly influenced by the mixtures of water-soluble nacre proteins. At very low protein concentrations (0.02 μg/ml) a rate enhancement in comparison to the pure supersaturated calcium carbonate solution by a factor of 1.4 was observed. At higher protein concentrations, a strong inhibitory effect occurred, with total inhibition at concentrations of 1.0 μg/ml and higher. Two unspecific proteins (bovine serum albumin and lysozyme) showed little or no modification of precipitation rates. In vivo, the function of the strong inhibition of CaCO₃ precipitation by nacre proteins at higher concentrations is presumably to prevent uncontrolled crystallization in the extrapallial fluid. The rate-enhancing capability of proteins at low concentrations may be explained by the presence of acidic and/or hydrophilic moieties.