T型薄壁管节点应力集中系数有限元分析

通过有限元的方法,分析了T型薄壁管节点受平面内弯矩作用下的疲劳行为,得到了应力最大值的位置和拟合出用于预测T型薄壁管节点受平面内弯矩作用下的应力集中系数的参数公式。     

工程结构动态特性智能优化设计研究

本文针对在传统结构优化设计中，优化过程复杂和费时的问题，采用神经网络的智能算法对结构进行动态优化设计，并给出了具体的设计方法。以门座起重机筒型支柱结构为例，应用此方法对其进行了动态优化设计计算，从而证明了该算法的有效性。     

石油加工中生物脱硫技术的进展

文中对石油加工过程中原料及其产品的生物脱硫工艺技术研究和应用的现状进行了分析和展望,并提出了当今世界生物技术在炼油工业中的发展前景.     

农村饮水工程适宜水质净化技术

农村饮水工程根据不同的原水水质条件，宜采用不同的水质净化技术。对地表水浑浊度长年低于20NTU、瞬间不超过60NTU原水，可采用微絮凝直接过滤加消毒或慢滤加消毒净化工艺；浑浊度长年低于500NTU、瞬间不超过1000NTU的原水，采用混凝沉淀（澄清）过滤、消毒的常规净水工艺。对于特殊水质如氟超标的地下水、砷超标的地下水、苦咸水及其他污染水，根据不同情况，可分别采用活性氧化铝吸附法、混凝沉淀法、多介质过滤法、铁盐混凝沉淀法、电渗析法、反渗透法等不同方式予以处理。     

In utero exchange transfusion in homozygous alpha-thalassaemia: a case report

We report a case of homozygous alpha-thalassaemia with hydrops fetalis presenting at 22 weeks of gestation. In utero exchange transfusion was performed with maternal blood at 23 weeks. 25 weeks and 29 weeks of gestation. The fetus was delivered at 29 weeks of gestation without significant neonatal complication. Post-transfusion haemoglobin pattern after transfusion suggested that a total haematocrit of 0.52 may be the desired post-exchange transfusion haematocrit to aim for and the total haematocrit of haemoglobin A and haemoglobin Portland dropped approximately one percent per day.     

高炉喷吹半焦的可行性

本文介绍了煤的热解和半焦性质。煤在快速热解过程中脱除热解水、焦油、部分的硫和煤气。半焦含有比煤低的硫含量和较高的热值。半焦的可磨性、反应性及燃烧性都比煤好，因此，半焦是高炉理想的喷吹燃料。     

模糊技术的发展及在相关领域中的应用

本文介绍了模糊技术的发展和现状，以及在相关领域中的应用情况，并且讨论了模糊技术在我国的产业化方向等问题。     

Dysregulated cyclin D1 expression early in head and neck tumorigenesis: in vivo evidence for an association with subsequent gene amplification

Cyclin D1 proto-oncogene is a key regulator of the mammalian cell-cycle acting at the restriction point in late G1. Amplification of the cyclin D1 locus, located on chromosome 11q13, as well as cyclin D1 protein overexpression have been reported in several human malignancies. The purpose of this study was to evaluate cyclin D1 gene copy status and protein expression during the multistep process of head and neck tumorigenesis, using a combination of fluorescence in situ hybridization and immunohistochemistry techniques. From 29 selected patients presenting with head and neck squamous carcinoma and whose tumor cytospins had been previously screened for presence (16 cases) or absence (13 cases) of amplification at the 11q13 band, we analysed 46 paraffin-embedded tissue specimens that demonstrated, besides the primary tumor, the presence of contiguous adjacent normal tissue and/or premalignant lesions. Of the 16 amplified cases, nine demonstrated a continuous progression from premalignant to invasive carcinoma and seven (77.7%) of these cases showed cyclin D1 gene amplification in premalignant lesions prior to development of invasive carcinoma. Increased cyclin D1 protein expression was observed in all 16 amplified tumors and five of the 13 (38.4%) non-amplified tumors. Interestingly, dysregulated cyclin D1 expression was also found in the premalignant lesions adjacent to all 16 amplified tumors, and it appeared to precede cyclin D1 gene amplification. In contrast no dysregulated expression was detected in the premalignant lesions of the non-amplified tumors. In conclusion, these findings provide strong evidence for early dysregulation of cyclin D1 expression during the tumorigenesis process and suggest that dysregulated increased expression precedes and possibly enables gene amplification.     

As,Sb,Sn对30CrMnSiA钢力学性能的影响

在３０ＣｒＭｎＳｉＡ钢中加入不同量的Ａｓ，Ｓｂ，Ｓｎ元素，研究了这些元素单独存在及复合存在时对钢的强度，塑性，冲击韧度及韧脆转变温度的影响规律，并用扫描电镜及俄歇能谱分析了Ａｓ，Ｓｂ，Ｓｎ导致晶界脆化的机理。