Preparation and nonlinear optical response of novel palladium-containing micellar nanohybrids

The synthesis and characterization of novel micellar nanohybrids with controllable sizes consisting of palladium nanosized core and covered by well-defined poly(lauryl methacrylate)-block-poly(2-(acetoacetoxy)ethyl methacrylate) (pLauMA-b-pAEMA) diblock copolymers are reported. Their nonlinear optical (NLO) response (i.e. nonlinear refraction and absorption and the third-order susceptibility χ⁽³⁾) is also studied under 35 ps laser excitation both in the visible and in the infrared and found to be insensitive to the size of the micelles while it was found to be greatly affected by the molar fraction of the AEMA block. To the best of our knowledge it is the first time that such Pd micellar nanohybrids are synthesized and investigated towards their NLO properties. The magnitude of the nonlinear optical response of these nanohybrids renders them promising candidates for potential optoelectronic applications.     

Application of microfiltration to egg white depleted in ovomucin

Summary An attempt was made to reduce the microbial load of unpasteurized fresh egg white by using cross-flow microfiltration and a Tetra-Laval bactocatch installation. Cross-flow tangential microfiltration of liquid fresh egg white was not feasible as there was irreversible membrane clogging within a few minutes of operation. As membrane clogging could have been caused by ovomucin, this protein was removed from whole fresh egg white by increasing the salt strength and lowering the pH. Ovomucin-depleted egg white (ODEW) was successfully microfiltered on the same membrane. Compared to fresh egg white, ODEW had lower foaming and viscous properties, and these properties remained unchanged after bactofiltration. The reduction of microbial load was, however, relatively low.     

Using a molten organic conducting material to infiltrate a nanoporous semiconductor film and its use in solid-state dye-sensitized solar cells

We describe a method to fill thin films of nanoporous TiO₂ with solid organic hole-conducting materials and demonstrate the procedure specifically for use in the preparation of dye-sensitized solar cells. Cross-sections of the films were investigated by scanning electron microscopy and it was observed that a hot molten organic material fills pores that are 10 μm below the surface of the film. We characterized the incident photon to current conversion efficiency properties of the solid TiO₂/organic dye/organic hole-conductor heterojunctions and the spectra show that the dye is still active after the melting process.     

Critical Review of the Evolution of Extracellular Vesicles’ Knowledge: From 1946 to Today

Extracellular vesicles (EVs) are a family of particles/vesicles present in blood and body fluids, composed of phospholipid bilayers that carry a variety of molecules that can mediate cell communication, modulating crucial cell processes such as homeostasis, induction/dampening of inflammation, and promotion of repair. Their existence, initially suspected in 1946 and confirmed in 1967, spurred a sharp increase in the number of scientific publications. Paradoxically, the increasing interest for EV content and function progressively reduced the relevance for a precise nomenclature in classifying EVs, therefore leading to a confusing scientific production. The aim of this review was to analyze the evolution of the progress in the knowledge and definition of EVs over the years, with an overview of the methodologies used for the identification of the vesicles, their cell of origin, and the detection of their cargo. The MISEV 2018 guidelines for the proper recognition nomenclature and ways to study EVs are summarized. The review finishes with a “more questions than answers” chapter, in which some of the problems we still face to fully understand the EV function and potential as a diagnostic and therapeutic tool are analyzed.     

玛丽蒂姆会议酒店,柏林,德国

立面、周边环境以及对所在街区的一系列回应,是玛丽蒂姆酒店的设计要点。这个占地约1.2万m2的酒店基地紧邻文化中心（Kulturforum）和著名的文物保护建筑贝壳屋（Shellhaus,建筑师：Emil Fahrenkamp）,且距国家美术馆和波茨坦广场不远。     

Container effects on the free drainage of wet foams

This work studies how drainage of a wet foam is affected by certain characteristics of its container: diameter, wettability and shape of the walls. Drainage is registered by three simultaneous techniques: (a) electrical conductance measurements for the evolution of the local liquid fraction, (b) close-up photos for the evolution of the local bubble size distribution and (c) volumetric measurements for the evolution of the global liquid fraction in the entire container. Electrical measurements are conducted at different heights along the foam with the aid of several pairs of non-intrusive ring electrodes. Three cylindrical Plexiglas containers of different diameter are used, before and after treatment of their walls to allow tests with hydrophobic and hydrophilic walls, respectively. To resemble the shape of common industrial containers, the lower part of the largest container has a gradually reducing diameter towards its bottom. Foam decay is slower in the hydrophobic containers, this being less evident as diameter increases. Moreover, the role of diameter and shape is complex since the highest drainage rate is measured at the largest container whereas the lowest one at the medium container. The possible effect of the container walls in promoting the macroscopic rigidity of the foam structure is discussed     

Exploring the universality of personality judgments: Evidence from the great transformation (1000 BCE–200 BCE).

We examined whether personality judgments were present in texts of the diverse religious and philosophical traditions that emerged during the Great Transformation, an era spanning roughly 1000 BCE to 200 BCE. Some psychologists have suggested that the tendency of humans to judge personality has evolved; if some ancient societies failed to record personality judgments, it would be evidence against such an evolutionary position. In addition, learning about the prevalence and specifics of ancient personality judgments can help psychologists better understand the prehistory of personality psychology. Eight cultural traditions were studied: two each from China (Confucianism, Taoism), Greece (Classical and Hellenistic philosophy), India (Buddhism, Hinduism), and the Middle East (Judaism, Zoroastrianism). We found evidence that personality judgments were an important aspect of all of these traditions. Not only did people judge one another, but they also offered instructions on how to judge others. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Coping With Chronic Lower Back Pain: Designing and Testing the Online Tool ONESELF

A website was designed in order to help patients with chronic lower back pain (cLBP) to cope with their condition, relying on the concept of health literacy. A sample of 748 chronic or potentially chronic LBP patients were asked to regularly visit the site for a period of 12 months. The intervention was evaluated quantitatively (both preuse and postuse surveys, logfiles) and qualitatively. Users appear to have taken less painkillers than before in the period they accessed the site. Most users reported that the site contributed to increasing their knowledge, and helped them managing their back pain. Communication with doctors, family, and colleagues improved. Qualitative evaluation showed several positive effects including self‐comprehension, improvement of argumentative abilities, orientation, and self‐confidence.     

Cancer Stem Cells: Biological Functions and Therapeutically Targeting

Almost all tumors are composed of a heterogeneous cell population, making them difficult to treat. A small cancer stem cell population with a low proliferation rate and a high tumorigenic potential is thought to be responsible for cancer development, metastasis and resistance to therapy. Stem cells were reported to be involved in both normal development and carcinogenesis, some molecular mechanisms being common in both processes. No less controversial, stem cells are considered to be important in treatment of malignant diseases both as targets and drug carriers. The efforts to understand the role of different signalling in cancer stem cells requires in depth knowledge about the mechanisms that control their self-renewal, differentiation and malignant potential. The aim of this paper is to discuss insights into cancer stem cells historical background and to provide a brief review of the new therapeutic strategies for targeting cancer stem cells.