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Multimedia Tools and Applications - While denoising 3D MRI, structural preservation is a very critical process in the medical region. However, Rician noise in MRI has affected the image quality...  相似文献   
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Glycation, a nonenzymatic reaction between reducing sugars and proteins, is a proteome wide phenomenon, predominantly observed in diabetes due to hyperglycemia. Glycated proteome of plasma, kidney, lens, and brain are implicated in the pathogenesis of various diseases, including diabetic complications, neurodegenerative diseases, cancer, and aging. This review discusses the strategies to characterize protein glycation, its functional implications in different diseases, and intervention strategies to protect the deleterious effects of protein glycation.  相似文献   
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In-home technologies can support older adults' activities of daily living, provide physical safety and security, and connect elders to family and friends. They facilitate aging in place while reducing caregiver burden. One of older adults' primary concerns about in-home technologies is their potential to reduce human contact, particularly from cherished caregivers. In this exploratory in situ study, we provided an ecosystem of networked monitoring technologies to six older adults and their caregivers. We analyzed the amount and content of communication between them. The amount of noncomputer-mediated communication did not decrease through the 6-week study. The content of communication coalesced into four themes: communication about the technologies, communication facilitated by technologies, intrusiveness of technologies, and fun and playfulness with the technologies. Results suggest that in-home technologies, designed with sensitivity to older adults' primary motivations, have the potential to shape and tailor important relationships in later life.  相似文献   
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ABSTRACT

Singing, like dance, emerges directly from the body. The voice, in combination with whole body movement, constitutes a potent form of self-expression. Gestural systems offer a specialized context in which to explore the intersection between voice and movement. The practice-based investigation presented in this article charts the development of an original musical work, Intangible Spaces, which gives form to the invisible aspects of voice and movement through gestural control, physical modelling synthesis and visual feedback. I draw on embodied and performative autoethnographic methods to capture the felt sensations and sound-movement associations that arise during the composition process. I also explore the performance approaches of key practitioners in the area to gain a broader understanding of the ways in which musicians leverage existing performance skills to uncover novel connections between movement and voice in gestural performance.  相似文献   
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The purpose of this study was to examine individual differences in the effectiveness of learning objects in secondary school classrooms. Specifically, gender, age, grade, subject area, and computer comfort (self-efficacy) were examined in 850 students. Effectiveness was measured in terms of student attitude (learning, quality, and engagement) and student performance. No gender differences were observed between males and females with respect to student attitudes or performance. Age was significantly correlated with student attitudes and performance, however correlation coefficients were small. Grade 12 students were more positive about learning objects and performed better than grade 9 and 10 students. Science students had significantly more positive attitudes and performed better than mathematics students. Finally, students who were more comfortable about computers, appreciated learning objects more than their less confident peers, however performance was unaffected.  相似文献   
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Vir tual Environments (VEs) that use a real-walking locomotion interface have typically been restricted in size to the area of the tracked lab space. Techniques proposed to lift this size constraint, enabling real walking in VEs that are larger than the tracked lab space, all require reorientation techniques (ROTs) in the worst-case situation—when a user is close to walking out of the tracked space. We propose a new ROT using visual and audial distractors—objects in the VE that the user focuses on while the VE rotates—and compare our method to current ROTs through three user studies. ROTs using distractors were preferred and ranked more natural by users. Our findings also suggest that improving visual realism and adding sound increased a user's feeling of presence. Users were also less aware of the rotating VE when ROTs with distractors were used.  相似文献   
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Graph-Theoretical Analysis of the Swiss Road and Railway Networks Over Time   总被引:2,自引:1,他引:1  
Recent research of complex networks has significantly contributed to the understanding how networks can be classified according to its topological characteristics. However, transport networks attracted less attention although their importance to economy and daily life. In this work the development of the Swiss road and railway network during the years 1950–2000 is investigated. The main difference between many of the recently studied complex networks and transport networks is the spatial structure. Therefore, some of the well-established complex network measures may not be applied directly to characterise transport networks but need to be adapted to fulfil the requirements of spatial networks. Additionally, new approaches to cover basic network characteristics such as local network densities are applied. The focus of the interest hereby is always not only to classify the transport network but also to provide the basis for further applications such as vulnerability analysis or network development. It could be showed that the proposed measures are able to characterise the growth of the Swiss road network. To proof the use of local density measures to explain the robustness of a network however needs further research.
Kay W. AxhausenEmail:
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