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81.
Megumi Mae Mohammad Ibtehaz Alam Yasunori Yamashita Yukio Ozaki Kanako Higuchi S. M. Ziauddin Jorge Luis Montenegro Raudales Eiko Sakai Takayuki Tsukuba Atsutoshi Yoshimura 《International journal of molecular sciences》2021,22(22)
Dental calculus (DC) is a common deposit in periodontitis patients. We have previously shown that DC contains both microbial components and calcium phosphate crystals that induce an osteoclastogenic cytokine IL-1β via the NLRP3 inflammasome in macrophages. In this study, we examined the effects of cytokines produced by mouse macrophages stimulated with DC on osteoclastogenesis. The culture supernatants from wild-type (WT) mouse macrophages stimulated with DC accelerated osteoclastogenesis in RANKL-primed mouse bone marrow macrophages (BMMs), but inhibited osteoclastogenesis in RANKL-primed RAW-D cells. WT, but not NLRP3-deficient, mouse macrophages stimulated with DC produced IL-1β and IL-18 in a dose-dependent manner, indicating the NLRP3 inflammasome-dependent production of IL-1β and IL-18. Both WT and NLRP3-deficient mouse macrophages stimulated with DC produced IL-10, indicating the NLRP3 inflammasome-independent production of IL-10. Recombinant IL-1β accelerated osteoclastogenesis in both RANKL-primed BMMs and RAW-D cells, whereas recombinant IL-18 and IL-10 inhibited osteoclastogenesis. These results indicate that DC induces osteoclastogenic IL-1β in an NLRP3 inflammasome-dependent manner and anti-osteogenic IL-18 and IL-10 dependently and independently of the NLRP3 inflammasome, respectively. DC may promote alveolar bone resorption via IL-1β induction in periodontitis patients, but suppress resorption via IL-18 and IL-10 induction in some circumstances. 相似文献
82.
Naonori Sakamoto Shunji Araki Masahiro Yoshimura 《Journal of the American Ceramic Society》2009,92(S1):S157-S161
Eutectic melt solidification is shown to avoid cracking during solidification by quenching an amorphous phase. Subsequent annealing results in micro/nanostructure ceramics. This strategy has been applied to HfO2 –Al2 O3 –GdAlO3 and Y2 O3 –CaO–Al2 O3 ternary systems that have deep eutectics. In most cases, ceramic materials cracks when they are solidified from melt due to the thermal stress accumulated on the grain boundaries, the large specific volume difference between the melt and the crystalline solid, etc. The main reason why this strategy works is that a eutectic composition yields an amorphous phase from the melts by rapid cooling and the amorphous phase enables to design crystallization without cracking by postannealing. Appropriate postannealing for the quenched amorphous enables to control the crystallization behavior from the amorphous phase, which yields nanostructured composites without cracking. For the HfO2 –Al2 O3 –GdAlO3 case, the melt solidification and postannealing yields a nanocomposite with high transparency due to reduced scattering of 5–10 nm crystallites. For the Y2 O3 –CaO–Al2 O3 case, a plate-shaped bulk composite is obtained without cracking by molding the melt and postannealing. 相似文献
83.
Nakase Y. Morooka Y. Perlman D.J. Kolor D.J. Jae-Myoung Choi Shin H.J. Yoshimura T. Watanabe N. Matsuda Y. Kumanoya M. Yamada M. 《Solid-State Circuits, IEEE Journal of》1999,34(4):494-501
This paper describes a validation system for an SLDRAM interface. The SLDRAM system utilizes two techniques to achieve a high data-transfer rate with a conventional module mounting style. The first technique is a source-synchronization scheme. Since the chip that transmits data also supplies the data clock, the clock and data are completely synchronous. The second is the timing vernier technique. A wait time for output data is programmable in each SLDRAM. Therefore, the time at which data arrive at the controller from any SLDRAM can be set by the controller with a 200-ps step size. The validation chip is designed to emulate these operations. The chip is fabricated using a 0.35-μm CMOS process technology and packaged in a conventional 0.65-mm pitch thin small out-line package, mounted on a single-chip module, and put into an eight-module system. A stub series terminated logic (SSTL)-like interface is adopted for high-speed signals. From system-level measurements, the data eye width of 600 ps is obtained at a data rate of 600 Mbps. Errorless data transmission is observed in both read and write operations in a bit-error rate testing. The validation system has successfully demonstrated a data-transmission rate of 1.2 GB/s (600 Mbit/s/pin) using source-synchronization and timing vernier techniques at the supply voltage of 2.5 V 相似文献
84.
Tomohiro Yamaguchi Teruyoshi Yoshimura Tomohiko Yamakami Seiichi Taruta Kunio Kitajima 《Microporous and mesoporous materials》2008,111(1-3):285-291
New porous solids from alumina-pillared fluorine micas (APMs), which were obtained from synthetic Na-tetrasilicic fluorine mica [NaMg2.5Si4O10F2], were prepared by sulfuric acid-treatment under mild conditions at 25 °C. The products were investigated by XRD, ICP, SEM, TEM and N2 adsorption–desorption isotherm at 77 K. XRD measurements indicated that the interlayer pillared structure having a large basal spacing collapsed during the early stages of the acid-treatment. ICP analyses indicated that Al3+ and Mg2+ ions were leached out from the pillared micas during the acid-treatment. The pore properties of the leached products were found to differ from those of the mother pillared micas: the acid leaching of the pillared micas leads to the formation of mesopores around 3.2 nm in diameter. The correlation between the change in pore properties and cation elution behavior suggests that the mesopore formation results from the leaching of Mg2+ ions from the octahedral sheet of the pillared micas. The leached products thus obtained retained the flaky morphology of the mother pillared micas. These results show that the mild acid-treatment using APMs provides a novel route for obtaining unique mesopore solids having the large particle sizes of the mother micas. 相似文献
85.
This review describes the development and status of tracking research in Japan. First, the fundamentals of tracking and the influences of environmental stresses on tracking will be treated. Then, the principal tracking test methods currently in use will be characterized. Finally, some techniques for improving the tracking resistance of outdoor polymer insulating materials will be discussed 相似文献
86.
Tosaka T. Nagano I. Yagitani S. Yoshimura Y. 《Electromagnetic Compatibility, IEEE Transactions on》2005,47(2):352-360
In order to determine the relative permeability and conductivity of thin materials that could not be found using traditional methods, we constructed a shield box and developed a measuring system to estimate the unknown electric parameters of exotic shielding materials such as thin cloths. Thin electromagnetic shielding sheets of both nonmagnetic materials and ferromagnetic materials were used. The shielding effectiveness of the materials was measured as a function of frequency, and the results were compared with the calculated solutions for a multilayered model that was evaluated using the Sommerfeld integral that expresses near-field spherical waves by a composition of cylindrical waves. In these calculations, the relative permeability and conductivity were varied to determine the solution closest to the measured results. The least squares method was used to determine the best fitted values. Initially the nominal values of relative permeability were assumed, and the conductivity was found using the fitting technique. Then this determined value of the conductivity was assumed, and the relative permeability was found using the fitting technique. For the nonmagnetic materials, the estimated relative permeability was the same as the nominal values. For the ferromagnetic materials, the estimated relative permeability varied 0%-30% from the nominal values. For both types of materials, the estimated conductivities were 0%-9.8% different from nominal values. This research details a new method for evaluating the attenuation of interfering electromagnetic waves for thin materials. 相似文献
87.
Effect of carbonization temperature on the basic properties of woodceramics impregnated with liquefied wood 总被引:10,自引:0,他引:10
In this paper, a new woodceramics impregnated with liquefied wood is developed and the effect of carbonization temperature on the dimension shrinkage, weight loss, density, compressive strength, and volume electrical resistivity is investigated. The results show that, the higher the carbonization temperature is, the higher the dimension shrinkage is, the higher the compressive strength is, and the lower the electrical resistivity is. 相似文献
88.
Ruwan Gallage Atsushi Matsuo Takeshi Fujiwara Tomoaki Watanabe Nobuhiro Matsushita Masahiro Yoshimura 《Journal of the American Ceramic Society》2008,91(7):2083-2087
Crystalline CeO2 films and patterns have been successfully fabricated in a "single-step process" at moderate temperature. In this process, the combination of the ink-jet technique and depositing the precursor on a hot substrate (≤300°C) gave crystalline CeO2 without further heat treatment. X-ray diffraction analysis revealed that the phase formed was crystallized ceria with nanosized (<10 nm) crystallites. The film thickness was several hundred nanometers and the pattern width was about 150 μm. Scanning electron microscopy analysis showed that the films and patterns were free of cracks and adhered to the substrate. This is the first report about the direct patterning of crystalline CeO2 without postfiring or posttreatments like masking, etching, etc. 相似文献
89.
90.
Inés S. Neira Francisco Guitián Takaaki Taniguchi Tomoaki Watanabe Masahiro Yoshimura 《Journal of Materials Science》2008,43(7):2171-2178
We report an effective method for the synthesis of hydroxyapatite whiskers with sharp faceted hexagonal shape employing a
low temperature (90 °C) hydrothermal route with calcium nitrate tetrahydrate, diammonium phosphate and urea as starting materials.
The key parameters of the synthesis process i.e. duration, temperature cycle of the treatment and starting pH value are carefully
varied and the end products are investigated using powder X-ray diffraction (XRD), Raman-scattering, infrared spectroscopy
(IR), elemental analysis, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), transmission electron
microscopy (TEM), electron diffraction (ED), and high-resolution TEM (HRTEM) in order to find the optimal reaction conditions
that lead to the desired hexagonal morphology of HA whiskers. The results demonstrate that gradual and greater increase in
solution pH during the hydrothermal process favors large quantity of the single-crystalline hydroxyapatite whiskers with well
defined hexagonal morphology. 相似文献