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51.
Generalization performance of support vector machines (SVM) with Gaussian kernel is influenced by its model parameters, both the error penalty parameter and the Gaussian kernel parameter. After researching the characteristics and properties of the parameter simultaneous variation of support vector machines with Gaussian kernel by the parameter analysis table, a new area distribution model is proposed, which consists of optimal straight line, reference point of area boundary, optimal area, transition area, underfitting area, and overfitting area. In order to improve classification performance of support vector machines, a genetic algorithm based on change area search is proposed. Comparison experiments show that the test accuracy of the genetic algorithm based on change area search is better than that of the two-linear search method.  相似文献   
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A new extension of the conventional adaptive fuzzy sliding mode control (AFSMC) scheme, for the case of under-actuated and uncertain affine multiple-input multiple-output (MIMO) systems, is presented. In particular, the assumption for non-zero diagonal entries of the input gain matrix of the plant is relaxed. In other words, the control effect of one actuator can propagate from a subgroup of canonical state equations to the rest of equations in an indirect sense. The asymptotic stability of the proposed AFSM control method is proved using a Lyapunov-based methodology. The effectiveness of the proposed method for the case of under-actuated systems is investigated in the presence of plant uncertainties and disturbances, through simulation studies.  相似文献   
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Raloxifene hydrochloride (RLX) is a selective estrogen receptor modulator which is orally used for treatment of osteoporosis and prevention of breast cancer. The drug has low aqueous solubility and bioavailability. The aim of the present study is to formulate and characterize oil-in-water microemulsion systems for oral delivery of RLX. To enhance the drug aqueous solubility, microemulsion based on sesame oil was prepared. Sesame oil and Tween 80 were selected as the drug solvent oil and surfactant, respectively. In the first and second formulations, Edible glycerin and Span 80 were applied as co-surfactant, respectively. Pseudo-ternary phase diagrams showed that the best surfactant/co-surfactant ratios in the first and second formulations were 4:1 and 9:1, respectively. The particle size of all free drug-loaded and drug loaded samples were in the range of 31.25?±?0.3?nm and 60.9?±?0.1?nm, respectively. Electrical conductivity coefficient and refractive index of all microemulsion samples confirmed the formation of oil-in-water type of microemulsion. In vitro drug release profile showed that after 24?hours, 46% and 63% of the drug released through the first formulation in 0.1% (w/v) Tween 80 in distilled water as a release medium and phosphate buffer solution (PBS) at pH?=?5.5, respectively. These values were changed to 57% and 98% for the second formulation. Results confirmed that the proposed microemulsion system containing RLX could improve and control the drug release profile in comparison to conventional dosage form.  相似文献   
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Many scientific fields increasingly use high-performance computing(HPC)to process and analyze massive amounts of experimental data while storage systems in today's HPC environments have to cope with new access patterns.These patterns include many metadata operations,small I/O requests,or randomized file I/O,while general-purpose parallel file systems have been optimized for sequential shared access to large files.Burst buffer file systems create a separate file system that applications can use to store temporary data.They aggregate node-local storage available within the compute nodes or use dedicated SSD clusters and offer a peak bandwidth higher than that of the backend parallel file system without interfering with it.However,burst buffer file systems typically offer many features that a scientific application,running in isolation for a limited amount of time,does not require.We present GekkoFS,a temporary,highly-scalable file system which has been specifically optimized for the aforementioned use cases.GekkoFS provides relaxed POSIX semantics which only offers features which are actually required by most(not all)applications.GekkoFS is,therefore,able to provide scalable I/O performance and reaches millions of metadata operations already for a small number of nodes,significantly outperforming the capabilities of common parallel file systems.  相似文献   
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Tantalum carbide (TaC) is investigated as a potential support for oxygen evolution reaction electrocatalysts. It is ball milled with zirconia balls for 7 and 14 days. The particle size and surface area of the ball milled TaC are analyzed using scanning electron microscopy and nitrogen physisorption methods, respectively. After 14 days of ball milling, the TaC shows smaller particle size and larger surface area compared to after 7 days of ball milling and unmilled TaC. The long-term electrochemical stability of the ball milled TaC is evaluated under oxygen evolution reaction conditions using cyclic voltammetry and chronoamperometry. The ball milled support at a fixed voltage of 1.6 V is shown to be stable up to 5000 cycles. Chronoamperometric measurement also shows the ball milled TaC remains stable over the 70 h of the test.  相似文献   
56.
This study reported the fabrication and characterization of an electrospun wound dressing composed of polyvinyl alcohol (PVA), nanochitosan (NC), and Artemisia ciniformis extract (AE). NC and AE wt% were defined as process parameters, and their effects on the diameter, mechanical properties, and cell attachment of the fibers were investigated using the Design Expert 7.0 software. The software provided quadratic equations, which were investigated statistically and graphically, confirmed that with the increase in the NC portion in the samples, the mechanical strength and fiber diameter increased. The increase is probably due to the proper dispersion of nanoparticle into a PVA matrix and the increased viscosity of the solution; however, cell viability showed an increasing/decreasing trend. The presence of AE lowered the mechanical properties of the samples while positively affecting cell viability. Furthermore, the samples had significant antibacterial properties against Escherichia coli as Gram-negative bacteria and Staphylococcus aureus as Gram-positive one, a notable property for wound dressings. Overall, our findings showed that PVA/NC/AE has an excellent potential for use in biomedical fields, particularly as a wound dressing.  相似文献   
57.
Neural Computing and Applications - Achieving proper nonlinear properties and autocorrelation in the S-box structure is an open challenge in cryptography. Besides, there have been numerous articles...  相似文献   
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Some physicochemical and microstructural characteristics of hard‐to‐cook (HTC) and easy‐to‐cook (ETC) pinto beans and small‐type lentils were compared. The development of HTC seeds was monitored over 6 months for changes in physicochemical properties. Results indicated that hardness, extent of water absorption and solid loss of HTC legumes were, respectively, 21–97%, 7–72% and 62–236% higher than those of ETC legumes. In addition, darkening of HTC beans and lentils was significantly higher than those of ETC ones. Scanning electron microscope observations indicated deteriorations in cytoplasmic contents of cotyledon cells of hard seeds. Phytic acid and total phenolic contents were, respectively, decreased 36–61% and 43–61% during storage, whereas hardness of seeds was increased 3–6 times. The soaking of hard seeds in sodium solutions resulted in the improvement in legume texture.  相似文献   
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