Power output of a pulsed Raman laser with saturable excitation

A theoretical expression is obtained for the time dependence of the Stokes power output of a pulsed Raman laser, the pump pulse duration being comparable to the relaxation time of the Raman excitation and the output saturation limited. A rate-equation approach is employed, and the pump beam is assumed to have a Gaussian intensity distribution. The theory is developed in terms of the practical example, stimulated spin-flip Raman scattering in InSb.     

Lowpass digital filters using least-squared-error design

A method is presented of designing digital filters which give a least-squared-error fit to a polynomial expression. An example is given of a second-order digital-filter approximation to a first-order continuous filter.     

Theory of spin-flip laser modes--II: Higher modes and saturation effects

Results are presented for the threshold input power and tuning characteristics of the higher (transverse) modes of the spin-flip Raman laser. It is concluded that the fundamental mode has the lowest threshold for all cases of interest in the model which we have used. Effects of spin saturation on the fundamental mode are also analyzed, leading to an estimate of the magnitude of the variation of output frequency with input power. Coexistence of longitudinal modes in the vicinity of a mode hop is considered, but the conclusions are obscured by lack of knowledge of the relevant magnetic diffusion lengths.     

Complete nucleotide sequence of pSK41: evolution of staphylococcal conjugative multiresistance plasmids

The 46.4-kb nucleotide sequence of pSK41, a prototypical multiresistance plasmid from Staphylococcus aureus, has been determined, representing the first completely sequenced conjugative plasmid from a gram-positive organism. Analysis of the sequence has enabled the identification of the probable replication, maintenance, and transfer functions of the plasmid and has provided insights into the evolution of a clinically significant group of plasmids. The basis of deletions commonly associated with pSK41 family plasmids has been investigated, as has the observed insertion site specificity of Tn552-like beta-lactamase transposons within them. Several of the resistance determinants carried by pSK41-like plasmids were found to be located on up to four smaller cointegrated plasmids. pSK41 and related plasmids appear to represent a consolidation of antimicrobial resistance functions, collected by a preexisting conjugative plasmid via transposon insertion and IS257-mediated cointegrative capture of other plasmids.     

Crab clocks rewound

The effect of amphetamine (AMPH), codeine (COD), methamphetamine (MEPH), morphine (MORP), and benzoylecgonine (BE) on the binding of cocaethylene (CE) and cocaine (COC) to human serum in vitro was investigated by equilibrium dialysis at 4 degrees C. Each compound was added individually at concentrations of 500, 1,000, or 2,000 nM to pooled human serum containing COC or CE at 500 nM concentration. For COC, the addition of COD, MEPH, and CE enhanced serum binding whereas MORP and BE decreased it. Variable effects on COC binding were noted for AMPH. For CE, the addition of COD and COC generally increased binding whereas MORP decreased it. No appreciable effect on CE binding was observed after adding AMPH, MEPH, and BE. Except for CE, AMPH, and MEPH in the presence of COC, the binding of COC and CE tended to be less with 2,000 nM of each added drug than at lower concentrations of them, presumably because of mass-action displacement of COC and CE at the higher concentration. These findings should be clinically important because these drugs are frequently found together in patients.     

Is the donut in front of the car? An electrophysiological study examining spatial reference frame processing.

Notes that the process of describing an object's location relative to another object results in ambiguity. How do people handle this ambiguity? The present 3 studies, using a total of 88 undergraduates, examined spatial language processing when use of different reference frames results in ambiguity. This study investigated whether electrophysiological measures of cognitive processing may elucidate underlying reference frame processing; in particular, the authors were interested in semantic integration. Electrophysiological results show a larger N400, peaking between 300 and 375 ms, when the intrinsic frame was not used. Behavioral results mirrored this finding, indicating a reduced cognitive processing requirement for the intrinsic reference frame. Previous work has not definitively tied spatial reference frame processing to specific electrophysiological components and their associated cognitive processes. Although the N400 peak seen in this data is early, additional work supports the N400 interpretation, thereby linking spatial frame processing to semantic integration. Results are discussed within the larger context of spatial reference frame processing. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Converting discrete images to partitioning trees

The discrete space representation of most scientific datasets, generated through instruments or by sampling continuously defined fields, while being simple, is also verbose and structureless. We propose the use of a particular spatial structure, the binary space partitioning tree as a new representation to perform efficient geometric computation in discretely defined domains. The ease of performing affine transformations, set operations between objects, and correct implementation of transparency makes the partitioning tree a good candidate for probing and analyzing medical reconstructions, in such applications as surgery planning and prostheses design. The multiresolution characteristics of the representation can be exploited to perform such operations at interactive rates by smooth variation of the amount of geometry. Application to ultrasound data segmentation and visualization is proposed. The paper describes methods for constructing partitioning trees from a discrete image/volume data set. Discrete space operators developed for edge detection are used to locate discontinuities in the image from which lines/planes containing the discontinuities are fitted by using either the Hough transform or a hyperplane sort. A multiresolution representation can be generated by ordering the choice of hyperplanes by the magnitude of the discontinuities. Various approximations can be obtained by pruning the tree according to an error metric. The segmentation of the image into edgeless regions can yield significant data compression. A hierarchical encoding schema for both lossless and lossy encodings is described     

Developing control and integration software for flexible manufacturing systems

The slow growth of computer-integrated manufacturing is attributed to the complexity of designing and implementing their control and integration software. This article expands on a methodology for designing and implementing this software that was introduced in [16]. The goal of this methodology is to build flexible and resuable control and integration software for computer-integrated manufacturing systems. It hinges upon the concepts of software/hardware components, their assemblages, a distributed common language environment, formal models, and generic controllers. Major sources of flexibility are obtained by decoupling process plan models from the model of the factory floor and by using a generic controller. Reusability is achieved by building selfcontained software/hardware components with general, possibly parametrized, interfaces. The interplay between simulated and actual hardware internals of software/hardware components is used as the basis of a testing strategy that performs off-line simulation followed by on-line testing.The methodology has been applied in designing and implementing the control and integration software of an actual Prismatic Machining Cell. The article also reports on the details of this implementation.The names of the authors appear in alphabetical order.