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241.
Mokhtar Bozorg Antonio Bracale Pierluigi Carami Guido Carpinelli Mauro Carpit Pasquale De Falco 《电力系统保护与控制》2020,5(3):36-47
泛在电力物联网是应对海量综合能源设备、数据和业务计算负荷的关键,云计算是泛在电力物联网的关键技术。云数据中心是云计算架构核心,云数据中心选址对云计算性能意义重大。变电站是能量流、业务流和信息流的核心节点,且有建设数据中心的有利资源,分布式架构可以高效利用变电站资源。因此,基于变电站建设多站融合的分布式云数据中心是支持泛在电力物联网的有效方式。首先考虑能量流、业务流和信息流的关系,分析变电站特性,提出基于变电站的分布式云计算架构。然后针对该架构提出云数据中心优化选址策略。最后基于案例对优化选址策略进行仿真,证明了优化策略的有效性。 相似文献
242.
Angelica Dessì Antonio Murgia Rocco Agostino Maria Grazia Pattumelli Andrea Schirru Paola Scano Vassilios Fanos Pierluigi Caboni 《International journal of molecular sciences》2016,17(2)
In this study, a gas-chromatography mass spectrometry (GC-MS) metabolomics study was applied to examine urine metabolite profiles of different classes of neonates under different nutrition regimens. The study population included 35 neonates, exclusively either breastfed or formula milk fed, in a seven-day timeframe. Urine samples were collected from intrauterine growth restriction (IUGR), large for gestational age (LGA), and appropriate gestational age (AGA) neonates. At birth, IUGR and LGA neonates showed similarities in their urine metabolite profiles that differed from AGA. When neonates started milk feeding, their metabolite excretion profile was strongly characterized by the different diet regimens. After three days of formula milk nutrition, urine had higher levels of glucose, galactose, glycine and myo-inositol, while up-regulated aconitic acid, aminomalonic acid and adipic acid were found in breast milk fed neonates. At seven days, neonates fed with formula milk shared higher levels of pseudouridine with IUGR and LGA at birth. Breastfed neonates shared up-regulated pyroglutamic acid, citric acid, and homoserine, with AGA at birth. The role of most important metabolites is herein discussed. 相似文献
243.
Pierluigi Giampaolino Virginia Foreste Claudia Di Filippo Alessandra Gallo Antonio Mercorio Paolo Serafino Francesco Paolo Improda Paolo Verrazzo Giuseppe Zara Cira Buonfantino Maria Borgo Gaetano Riemma Chiara De Angelis Brunella Zizolfi Giuseppe Bifulco Luigi Della Corte 《International journal of molecular sciences》2021,22(4)
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease. The hypothesis that alterations in the microbiome are involved in the genesis of PCOS has been postulated. Aim of this review is to summarize the available literature data about the relationship between microbiome and PCOS. A search on PubMed and Medline databases was performed from inception to November 20Most of evidence has focused on the connection of intestinal bacteria with sex hormones and insulin-resistance: while in the first case, a relationship with hyperandrogenism has been described, although it is still unclear, in the second one, chronic low-grade inflammation by activating the immune system, with increased production of proinflammatory cytokines which interfere with insulin receptor function, causing IR (Insulin Resistance)/hyperinsulinemia has been described, as well as the role of gastrointestinal hormones like Ghrelin and peptide YY (PYY), bile acids, interleukin-22 and Bacteroides vulgatus have been highlighted. The lower genital tract microbiome would be affected by changes in PCOS patients too. The therapeutic opportunities include probiotic, prebiotics and synbiotics, as well as fecal microbiota transplantation and the use of IL-22, to date only in animal models, as a possible future drug. Current evidence has shown the involvement of the gut microbiome in PCOS, seen how humanized mice receiving a fecal transplant from women with PCOS develop ovarian dysfunction, immune changes and insulin resistance and how it is capable of disrupting the secondary bile acid biosynthesis. A future therapeutic approach for PCOS may involve the human administration of IL-22 and bile acid glycodeoxycholic acid. 相似文献
244.
Blending green hydrogen within the gas infrastructure is seen as the first move towards Europe's climate neutrality by 2050. Especially, Europe and North African have privileged role in energy cooperation sharing a woven and complex set of natural resources, knowledge, infrastructure, clear goals towards sustainable development. Developing common projects about hydrogen can mutually help both Europe and North Africa to achieve more sustainable, reliable and modern energy systems.This paper simulates the Greenstream gas corridor (connecting Libya to Italy) under increasing hydrogen blending scenarios using a transient and multi-component fluid-dynamic model of the gas transmission system.The additional compression energy required and the compressors’ operating hours are evaluated under the hypothesis that the energy content of the transported gas is maintained. The hydrogen profiles needed to generate the blends are obtained and used to optimally size a photovoltaic-powered electrolysis system, minimizing the compressed hydrogen storage.The results indicate that the additional energy costs of transporting hydrogen blends are up to 32.5% higher than natural gas transport, while negligibly impacting the overall efficiency of energy transport. The mismatch between solar hydrogen production and pipeline receiving potential highlights a challenge to be tackled to boost intersectoral integration. 相似文献
245.
Mathieu Mirjolet Hari Babu Vasili LLuís Lpez‐Conesa Snia Estrad Francesca Peir Jos Santiso Florencio Snchez Pamela Machado Pierluigi Gargiani Manuel Valvidares Josep Fontcuberta 《Advanced functional materials》2019,29(37)
Transparent metallic oxides are pivotal materials in information technology, photovoltaics, or even in architecture. They display the rare combination of metallicity and transparency in the visible range because of weak interband photon absorption and weak screening of free carriers to impinging light. However, the workhorse of current technology, indium tin oxide (ITO), is facing severe limitations and alternative approaches are needed. AMO3 perovskites, M being a nd1 transition metal, and A an alkaline earth, have a genuine metallic character and, in contrast to conventional metals, the electron–electron correlations within the nd1 band enhance the carriers effective mass (m*) and bring the transparency window limit (marked by the plasma frequency, ωp*) down to the infrared. Here, it is shown that epitaxial strain and carrier concentration allow fine tuning of optical properties (ωp*) of SrVO3 films by modulating m* due to strain‐induced selective symmetry breaking of 3d‐t2g(xy, yz, xz) orbitals. Interestingly, the DC electrical properties can be varied by a large extent depending on growth conditions whereas the optical transparency window in the visible is basically preserved. These observations suggest that the harsh conditions required to grow optimal SrVO3 films may not be a bottleneck for their future application. 相似文献