Optimal heat exchanger network synthesis with operability and safety considerations

Research on the optimal design of heat exchanger networks (HENs) has primarily revolved around trading off technical design requirements for aspects of economy, such as capital cost of heat exchangers and utilities. As a result, considerations for safety, operability, and flexibility have received much less attention. This study presents a Pinch Analysis-based methodology that considers the inherent safety and operability aspects of an optimal HEN design. The procedure begins with data extraction, followed by utility targeting that gives due consideration to how each process stream impacts the inherent safety of the HEN. This is made possible via the use of a hot and cold Stream Temperature versus Enthalpy Plot (STEP) that prioritises the inherent safety index (ISI) on top of the heat capacity flow rate (CPs) during simultaneous targeting and design of the HEN. The Pinch temperatures and minimum utilities were determined using STEP. At the same time, the hot and cold stream pairs with higher ISIs and those with lower ISIs were matched together so that safety considerations could be emphasised and precautions taken with a particular heat exchanger. The disturbance propagation path through the HEN and the affected streams were also analysed. Network modification was performed using the downstream path concept in order to reduce disturbance propagation downstream of the HEN. The ?T _min violations and energy penalties from network changes were assessed. Flexibility and structural controllability of each network option were compared. The highest percentage of change in every stream of the network indicates that network is the most flexible, while the index of structural controllability closest to 1 demonstrates that the network is most controllable. Application of this method within an illustrative case study showed that network 3 was the most flexible as it yielded the highest percentage of change at 22 %. It was also the most controllable as it had a controllability index closest to 1.0, i.e. at 0.917.     

Focused-Pulsed sludge pre-treatment increases the bacterial diversity and relative abundance of acetoclastic methanogens in a full-scale anaerobic digester

The low yield of methane in anaerobic digestion systems represents a loss of energy that can be captured as renewable energy when the input sludge is pre-treated to make it more bioavailable. We investigated Focused-Pulsed (FP) pre-treatment, which make complex biological solids more bioavailable by exposing them to rapid pulses of a very strong electric field. We investigated how the microbial ecology in full-scale anaerobic digesters was altered when the digesters' methane production rate was significantly increased by FP pre-treatment. Using clone libraries and quantitative PCR, we demonstrated a shift in methanogenic genera to the acetate-cleaving Methanosaeta and away from the H₂-oxidizing Methanoculleus. In addition, the acetate concentration in the effluent was very low, probably due to the dominance of Methanosaeta, which are capable of scavenging low acetate concentrations. By analyzing 36,797 pyrosequencing tags from the V6 region of the bacterial 16S rRNA gene, along with archaeal and bacterial clone libraries and quantitative PCR, we compared the microbial community composition before and after FP treatment. The bacterial community became more diverse after FP pre-treatment and was populated more by phylotypes associated with cellulose fermentation (Ruminococcus), scavenging of biomass-derived organic carbon (Chloroflexi), and homo-acetogenesis (Treponema). We interpret that, as the overall activity of the community was stimulated by addition of more bioavailable organic matter, the bacterial community became more phylogenetically diverse to take advantage of the added input of biodegradable material and in response to the more efficient utilization of acetate by Methanosaeta.     

Hydrogen production by Clostridium acetobutylicum ATCC 824 and megaplasmid-deficient mutant M5 evaluated using a large headspace volume technique

Biohydrogen production is measured using a variety of techniques, ranging from low cost intermittent gas release methods where yields are usually reduced due to high partial pressures of hydrogen, to expensive respirometers that can eliminate pressure buildup. A new large headspace volume technique was developed that reduces the potential for hydrogen gas inhibition without the need for a respirometer. We tested this method with two strains of clostridia, Clostridium acetobutylicum ATCC 824 and its mutant M5 that lacks a megaplasmid responsible for butanol and acetone production, and a mixed culture (heat-treated sludge). The hydrogen yield using M5 (2.64 mol-H₂/mol-glucose) was 47% higher than that of the parent strain (1.79 mol-H₂/mol-glucose), and 118% larger than that obtained in tests with the sludge inoculum (1.21 mol-H₂/mol-glucose). The increased yield for M5 was primarily due to a decrease in biomass synthesis (38%) compared to the parent strain. Hydrogen yields measured using this new method were on average 14% higher than those obtained using a conventional respirometric method. These findings indicate enhanced biohydrogen production from the megaplasmid-deficient mutant of C. acetobutylicum ATCC 824, and that an intermittent gas-sampling technique can effectively measure high hydrogen gas by using a large headspace volume.     

Non-visualization of lung markings below hemidiaphragm in subtle subpulmonic effusion: an old sign resuscitated

To assess the lack of visibility of vascular markings under the hemidiaphragm on a frontal chest radiograph as a sign of pleural effusion, fifteen patients were collected showing this sign. Pleural effusion was diagnosed by ultrasound, comparison with previous or subsequent chest x-ray or computed tomography. Patients in the study group exhibited this sign in the absence of the classical signs of pleural effusion. In the control group, lack of visibility of blood vessels was observed in only 4.2% cases. Non-visualization of vascular markings below the hemidiaphragm should alert the interpreter to the possible presence of pleural effusion and a lateral or decubitus view or ultrasound examination may be carried out to rule out effusion.     

Removal of leachate pollutants using flocculation method at simultaneous factors of optimum pH and Tacca leontopetaloides biopolymer flocculant (TBPF) dosage via face-centred central composite design

The effect of the interaction factor between pH and dosage is important in leachate wastewater treatment. This study aims to remove leachate pollutants such as turbidity, total suspended solid (TSS), chemical oxygen demand (COD) and colour using simultaneous factors of plant-based Tacca leontopetaloides biopolymer flocculant (TBPF) dosage and leachate pH. The flocculation process was carried out through jar test by applying the perikinetic theory and statical analysis (face-centred central composite design). The results found that the optimum leachate pH and TBPF dosage were pH 3 and 150 mg/L, respectively. The highest removal of leachate pollutants reached up to 69% with a second-order perikinetic model; R² = 0.9545 and k = 9 × 10⁻⁶ L/mg/min were obtained. Simultaneous interaction factors between leachate pH and TBPF dosage on turbidity and TSS removal were found significant and hence can be applied in the actual leachate wastewater treatment industry, particularly at the primary stage using the proposed model.