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Rolf Sachsse 《History of Photography》2013,37(3):301-304
Abstract Winding up the estate of somebody is a sad task, only sustained by the hope of unexpected finds or definitive proof of one's preconceived opinions. There is no difference in this between one's own grandmother and a contemporary like Lucia Moholy. While executing this task I naturally came across various documents that shifted my vague assumptions about this versatile woman in different directions. I saw photographs from her private life that enlightened me about her social relations but, in the end, I was disappointed at not havlng been able to get closer to a person I thought I knew quite well, even if from a certain distance.1 相似文献
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Riener Heinz Haedicke Finn Frehse Stefan Soeken Mathias Große Daniel Drechsler Rolf Fey Goerschwin 《International Journal on Software Tools for Technology Transfer (STTT)》2017,19(5):605-621
International Journal on Software Tools for Technology Transfer - Many applications from artificial intelligence and formal methods use decision procedures as their core solving engines. In this... 相似文献
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Prof. Dr. Ruth Birner‐Gruenberger Prof. Dr. Rolf Breinbauer 《Chembiochem : a European journal of chemical biology》2016,17(16):1488-1490
Recently, Hang and co‐workers developed “acyl‐PEG exchange” (APE), which allows the investigation of protein S‐fatty acylation with mass‐tag labelling and gel electrophoresis, methods that are accessible to any biochemistry laboratory. 相似文献
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Greg Mann Dr. Liujie Huo Sebastian Adam Dr. Brunello Nardone Dr. Jeremie Vendome Prof. Nicholas James Westwood Prof. Rolf Müller Dr. Jesko Koehnke 《Chembiochem : a European journal of chemical biology》2016,17(23):2286-2292
The bottromycins are a family of highly modified peptide natural products, which display potent antimicrobial activity against Gram‐positive bacteria, including methicillin‐resistant Staphylococcus aureus. Bottromycins have recently been shown to be ribosomally synthesized and post‐translationally modified peptides (RiPPs). Unique amongst RiPPs, the precursor peptide BotA contains a C‐terminal “follower” sequence, rather than the canonical N‐terminal “leader” sequence. We report herein the structural and biochemical characterization of BotP, a leucyl‐aminopeptidase‐like enzyme from the bottromycin pathway. We demonstrate that BotP is responsible for the removal of the N‐terminal methionine from the precursor peptide. Determining the crystal structures of both apo BotP and BotP in complex with Mn2+ allowed us to model a BotP/substrate complex and to rationalize substrate recognition. Our data represent the first step towards targeted compound modification to unlock the full antibiotic potential of bottro‐ mycin. 相似文献
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Adeel Nasir Peter Rolf Richter Aude Le Bail Viktor Daiker Julia Stoltze Binod Prasad Sebastian Michael Strauch Michael Lebert 《International journal of molecular sciences》2022,23(5)
Euglena gracilis is a photosynthetic flagellate. To acquire a suitable position in its surrounding aquatic environment, it exploits light and gravity primarily as environmental cues. Several physiological studies have indicated a fine-tuned relationship between gravity sensing (gravitaxis) and light sensing in E. gracilis. However, the underlying molecular mechanism is largely unknown. The photoreceptor photoactivated adenylyl cyclase (PAC) has been studied for over a decade. Nevertheless, no direct/indirect interaction partner (upstream/downstream) has been reported for PAC. It has been shown that a specific protein, kinase A (PKA), showed to be involved in phototaxis and gravitaxis. The current study reports the localization of the specific PKA and its relationship with PAC. 相似文献