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51.
Sijtze Stob Ruud M. Scheek Rolf Boelens Klaas Dukstra Robert Kaptein 《Israel journal of chemistry》1988,28(4):319-327
Photo-CIDNP is a useful technique to identify surface residues in proteins and to assign resonances in their 1H NMR spectra by the spectral simplification that is obtained. In spite of this simplification, conventional photo-CIDNP spectra can be quite complex due to spectral overlap. For this reason two-dimensional (2D) methods are welcome. We present combinations of photo-CIDNP with 2D J-correlated spectroscopy (CIDNP-COSY) and with 2D NOE spectroscopy (CIDNP-NOESY). In these experiments we insert a saturation pulse sequence and a short laser-irradiation period at the beginning of the preparation period to generate CIDNP, leaving the remaining of the pulse scheme essentially unaltered. The CIDNP-COSY and CIDNP-NOESY spectra of a hen egg-white (HEW) lysozyme are presented. The CIDNP-NOESY spectrum of lysozyme is compared with the results from 1D cross-polarisation experiments on the same protein. CIDNP-NOESY spectra of lysozyme with and without inhibitor NAG are compared. 相似文献
52.
Summary Living polystyrene microparticles with average particle diameters varying between 0.5 and 3.8 m were obtained via sec-butyl lithium-initated anionic polymerization of styrene in n-hexane diluent when polystyrene-block-poly(4-trimethyl-silylstyrene) was added as dispersing agent. The influence of block copolymer molecular architecture and concentration as well as polymerization temperature, monomer concentration and THF addition on polystyrene particle size, molecular weight and molecular weight distribution were investigated. In comparison to anionic styrene polymerization in cyclohexane solution, the anionic styrene dispersion polymerization in n-hexane was markedly slower. 相似文献
53.
Repeated administration of highly purified eicosapentaenoic acid (as ethyl ester) resulted in a decrease in plasma triglycerides
and high density lipoprotein (HDL) cholesterol. This was accompanied by a stimulation in the activities of carnitine palmitoyltransferase,
fatty acyl-CoA oxidase and peroxisomal β-oxidation in the liver. The results suggest that the triglyceride-lowering effect
observed with eicosapentaenoic acid may be due to a reduced supply of fatty acids for hepatic triglyceride synthesis because
of increased fatty acid oxidation. Eicosapentaenoic acid feeding marginally affected the triglyceride content of heart and
mitochondrial and peroxisomal enzyme activities. 相似文献
54.
55.
Online social networks (OSN) are technology-enabled relationship tools in which a user creates a profile, connects to other individuals, and shares user-generated content with them. One of the many features OSN offer is the ability to post messages in the form of product and service recommendations. Although word-of-mouth research has examined this type of personal communication to intentionally influence consumer decisions, limited understanding exists regarding when a user acts upon a recommendation received from one of their contacts. In this study, we draw on relationship theories and research on trust to analyze the impact relationship characteristics and behaviors of the OSN contacts have on trust in the recommendation that subsequently leads a user to act on this OSN contact’s recommendation. The results of a survey of 116 OSN users showed that closeness, excessive posting behavior, and past recommendation experience have a positive impact on trust and intention to act on the recommendation. One characteristic of the relationships, that is, similarity, however, does not affect recommendation trust in the context of OSN. The findings enhance our understanding of relationships and their defining characteristics in OSN. The results also provide insights into how companies might leverage OSN in their marketing efforts. 相似文献
56.
57.
The robustness of an architecture to changes is a major concern in the design of efficient and reliable state-of-the-art embedded real-time systems. Robustness is important during design process to identify if and in how far a system can accommodate later changes or updates, or whether it can be reused in a next generation product. In the product life-cycle, robustness helps the designer to perform changes as a result of product updates, integration of new components and subsystems, or modifications of the environment. In this paper we determine robustness as a performance reserve, the slack in performance before a system fails to meet timing requirements. This is measured as design sensitivity. Due to complex component interactions, resource sharing and functional dependencies, one-dimensional sensitivity analysis might not cover all effects that modifications of one system property may have on system performance. One reason is that the variation of one property can also affect the values of other system properties requiring new approaches to keep track of simultaneous parameter changes. In this paper we present a framework for one-dimensional and multi-dimensional sensitivity analysis of real-time systems. The framework is based on compositional analysis that is scalable to large systems. The one-dimensional sensitivity analysis combines a binary search technique with a set of formal equations derived from the real-time scheduling theory. The multi-dimensional sensitivity analysis engine consists of an exact algorithm that extends the one-dimensional approach, and a stochastic algorithm based on evolutionary search techniques. 相似文献
58.
Leonid B. Freidovich Pedro La Hera Uwe Mettin Anders Robertsson Anton S. Shiriaev Rolf Johansson 《Asian journal of control》2009,11(5):548-556
We consider an underactuated two‐link robot called the inertia wheel pendulum. The system consists of a free planar rotational pendulum and a symmetric disk attached to its end, which is directly controlled by a DC‐motor. The goal is to create stable oscillations of the pendulum, which is not directly actuated. We exploit a recently proposed feedback‐control design strategy based on motion planning via virtual holonomic constraints. This strategy is shown to be useful for design of regulators for achieving orbitally exponentially stable oscillatory motions. The main contribution is a step‐by‐step procedure on how to achieve oscillations with pre‐specified amplitude from a given range and an arbitrary independently chosen period. The theoretical results are verified via experiments with a real hardware setup. Copyright © 2009 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society 相似文献
59.
Nordahl R Turchet L Serafin S 《IEEE transactions on visualization and computer graphics》2011,17(9):1234-1244
We propose a system that affords real-time sound synthesis of footsteps on different materials. The system is based on microphones, which detect real footstep sounds from subjects, from which the ground reaction force (GRF) is estimated. Such GRF is used to control a sound synthesis engine based on physical models. Two experiments were conducted. In the first experiment, the ability of subjects to recognize the surface they were exposed to was assessed. In the second experiment, the sound synthesis engine was enhanced with environmental sounds. Results show that, in some conditions, adding a soundscape significantly improves the recognition of the simulated environment. 相似文献
60.
The paper addresses the problem of multi-slot just-in-time scheduling. Unlike the existing literature on this subject, it
studies a more general criterion—the minimization of the schedule makespan rather than the minimization of the number of slots
used by schedule. It gives an O(nlog 2
n)-time optimization algorithm for the single machine problem. For arbitrary number of m>1 identical parallel machines it presents an O(nlog n)-time optimization algorithm for the case when the processing time of each job does not exceed its due date. For the general
case on m>1 machines, it proposes a polynomial time constant factor approximation algorithm. 相似文献