Inhibition of natural killer cell cytotoxicity by cell growth-related molecules

Certain MHC class I molecules on target cells are known to inhibit the cytotoxic action of NK cells. By using monoclonal antibody (mAb) Cho-1, we have found inhibitory non-MHC class I cell surface molecules that are noncovalently-associated with 200 kDa and 40 kDa antigens. Poly I-C-induced rat NK cells were not cytotoxic to rat fetus-derived fibroblast WFB cell line. In contrast, NK cells were cytotoxic to H-ras oncogene-induced transformants of WFB, W14 and W31. FACS analysis indicated that mAb Cho-1 reacts with WFB, but not with W14 and W31 cells. Thus, this antigen may disappear concomitantly with cell growth and transformation. Cho-1 antigens were also expressed on other NK-resistant lines, such as mouse BALB3T3 fibroblast, EL-4 lymphoma and human fibroblast HEPM. However, they were not expressed on NK-sensitive mouse YAC-1 and H-ras transformant (Brash) of BALB3T3 cells. Furthermore, treatment of target cells with IFN-gamma clearly induced the cell surface expression of Cho-1 antigens, and conferred a resistance to NK cytolysis on target cells. These data strongly suggest that Cho-1 antigen expression may correlate with target cell susceptibility to NK cells. Indeed, treatment of NK-resistant WFB as well as HEPM cells with F(ab')2 fragments of mAb Cho-1 resulted in the acquisition of susceptibility to NK cytolysis. Cho-1 antigens may be novel molecules that regulate the NK resistance of cells.     

空泡溃灭水锤的VOF计算方法

空泡溃灭水锤是核电厂冷却循环系统中较常出现的一种严重的水锤事故。空泡的形成和溃灭是复杂的两相、瞬态过程，对于这一现象的分析是相当困难的。作者尝试着把蒸汽泡的边界看成是冷水流动的自由面，在自由面上考虑蒸汽的凝结。对于自由面的ＶＯＦ算法用了ＶＯＦ算法，取得了令人满意的结果，不仅形象地描绘了空泡的形成和溃灭的过程，而且得到了与实验相符的空泡溃灭高压和弥合速度，因此可为管道设计提供理论基础。     

Experimental studies of high frequency jet ventilation improved by enhancing expiratory turbulence

A 43-year-old male and a 39-year-old male presented with multiple pituitary adenomas with two distinct histological types. The first patient who had multiple endocrine neoplasia type 1 had developed acromegaly due to a growth hormone-releasing hormone (GHRH)-producing pancreatic tumor. Both plasma GHRH and growth hormone (GH) levels decreased to normal after resection of the pancreatic tumor. However, the plasma GH level gradually increased again and magnetic resonance imaging revealed pituitary adenoma formation. Histological examination revealed two different histological types of pituitary adenoma: GH cell adenoma and null cell adenoma. The second patient, with no such genetic condition, had a non-functioning pituitary adenoma. Histological examination revealed two different histological types of silent GH cell adenoma and silent gonadotroph adenoma. Careful histological examination is required to exclude the possibility of multiple pituitary adenomas.     

宽带被动导引头天线系统性能分析

详细讨论了宽带被动导引头中的关键部件－超宽频带天线的性能，并在此基础上分析了三种具备大视角特性的被动测角方法。由于宽带天线没有确定的相位中心，因此不能采用通常的振幅和差式单脉冲法进行宽频带测角。本文提出的波束运算网络可用于一个宽带螺旋天线同时得到两个交叉波束的振幅－振幅式单脉冲系统中。此外，对比幅相干测向法中的测角模糊问题也进行了研究。     

智能同步广播激励器及其标频

使用智能同步广播激励器,并采用CCTV传输的1MHz标频信号,就有可能实现自适应相位跟踪同步广播。这将大大节省中波段的频率资源。     

RELAP5程序与三维时空中子动力学模型的耦合以及改进研究

引入堆芯物理计算的两群三维时空中子动力学模型,对RELAP5程序的点堆中子动力学模型进行了改进,同时设计了可视化界面,可方便地实现人.机交互操作.计算结果与实际应用表明,改进后的RELAP5程序计算功能和精度得到提高,使用更加方便,在核动力装置的仿真方面有很好的应用前景.     

高能粒子辐照对零膨胀微晶玻璃光学性质和面形光学稳定性的影响

研究了高能电子，高能质子对ＶＯ２微晶玻璃辐照前后光性质和面形光学稳定性的影响，研究结果表明，高能电子辐照能引起微晶玻璃面形明显变化，且使ＶＯ２微晶玻璃强烈着色。高能质子辐照没引起面形明显变化，高能质子辐照对反射光谱特性没有影响。     

打管理基础 求科技支撑 取创新成效 全力履行精益保供核心使命

主要介绍了热电厂近几年来在技术管理方面取得的主要工作经验，以及围绕生产经营开展科技创新所取得的成绩，并且针对当前形势，进一步提出了热电厂今后一个时期科技工作的指导思想、任务目标和措施。     

悟

“悟”是一种对客观的事和物的一种感知,是对事和物获取了解、获取知效,是人们求得理解的一种启示、一种认识的过程。一般地说,“我对事和物,意在彻悟”,是指人们得到充分的悟性,特别对意、意义的悟,有的很快领会,有的要耗费时日,有的要经过一定的时间乃至终身。悟性就是理解的     

Pattern analysis of airborne dipole antenna in high-frequency region

The Uniform Geometrical Theory of Diffraction (UTD) has been successfully used in pattern analysis of airborne dipole antenna on the A-5 fighter in high-frequency region. In the analysis, several canonical problems are investigated first, then the complicated problem is calculated with compiling these canonical problems. The numerical results are compared with the experimental data, and good agreement has been seen. The effectiveness and practicality of the present analysis are thus verified.