Behavioral effects of centrally administered arginine vasopressin in the rat fetus.

Arginine–8 vasopressin (AVP) was administered to rat fetuses on Embryonic Day 20 via intracisternal (IC), intrahemispheric (IH), or intrathecal (IT) injection. The IC administration of AVP promoted a 4-fold increase in motor activity, including the uncommon patterns of mouthing, licking, and facial wiping. The IH injection of AVP had little effect on fetal behavior, but IT injection resulted in pronounced increases in fetal activity, including mouthing, licking, and wiping. The IT administration of a V? antagonist blocked AVP effects, whereas IH injection potentiated AVP-induced changes in fetal behavior. The IC blockade of V? receptors suppressed facial wiping to a chemosensory fluid (lemon) and reduced oral grasping of an artificial nipple, whereas IH injection of the V? antagonist promoted facial wiping responses and increased grasping of the nipple. These data suggest that AVP may play a role in the development of responsiveness to stimuli encountered in the context of suckling. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Behavioral effects of milk in the rat fetus.

Intraoral infusion of milk to the rat fetus promoted changes in behavior (mouth and rearlimb movements), reduced responsiveness to perioral cutaneous stimulation, and resulted in expression of a fetal stretch response. Milk also altered the temporal organization of fetal movements over periods up to 30 min. The orosensory characteristics of milk, in the absence of ingestion, was sufficient to evoke these behavioral effects. Reduced responsiveness to a perioral stimulus had a rapid onset (     

Optimal allocation of assessment time in randomized pretest-posttest designs.

The widely used pretest–posttest design traditionally consists of a pretest and a posttest of equal lengths. However, greater statistical power can usually be achieved by using a posttest that is somewhat longer than the pretest. This article provides a method for calculating the optimal allocation of pretest and posttest assessment units so as to maximize power and presents the accompanying reduction in required sample size for a range of parameter values. When insufficient information is available to estimate the optimal location precisely, the effects of allocating 75% of the assessment units to the posttest are evaluated. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sex stereotyping in Price Waterhouse v. Hopkins..

Comments on the article by S. T. Fiske et al (see record 1992-07509-001) praising the American Psychological Association's (APA's) amicus brief intended to inform the Supreme Court of current scientific thinking regarding gender stereotyping. A balanced perspective, it is argued, should include both research supporting an argument and findings that are inconsistent with that argument. The APA brief gave no indication of contradictory findings. Moreover, review of the research cited indicates that more than half of the studies do not support the argument for which they were cited. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Family preservation using multisystemic therapy: An effective alternative to incarcerating serious juvenile offenders.

Multisystemic therapy (MST) delivered through a community mental health center was compared with usual services delivered by a Department of Youth Services in the treatment of 84 serious juvenile offenders and their multiproblem families. Offenders were assigned randomly to treatment conditions. Pretreatment and posttreatment assessment batteries evaluating family relations, peer relations, symptomatology, social competence, and self-reported delinquency were completed by the youth and a parent, and archival records were searched at 59 wks postreferral to obtain data on rearrest and incarceration. In comparison with youths who received usual services, youths who received MST had fewer arrests and self-reported offenses and spent an average of 10 fewer weeks incarcerated. In addition, families in the MST condition reported increased family cohesion and decreased youth aggression in peer relations. The relative effectiveness of MST was neither moderated by demographic characteristics nor mediated by psychosocial variables. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Reactor modelling for electrochemical processes

This paper presents a relatively straightforward approach to the modelling of electrochemical reactors operated in batch or continuous modes. The models are based on ideal flow assumptions of either well-mixed or plug flow and incorporate reaction rate models based on electrochemical kinetics and mass transport at one electrode. General characteristics of the reactor models are described, particularly with regard to the need for good mass transport in metal recovery applications. An example is given on the use of the model in the recovery of a heavy metal (Cd²⁺) from an acidified solution containing Cd(II) and Fe(III) ions. The reaction rate model is based on experimental data.     

The mathematics of motif combination and their use for functional simulation

The concept of Motif Combination was introduced in the French Automotive industry's R&W standard. There has however been no formal mathematical theory for the technique of motif combination. This paper sets out to develop this theory. The main result of the paper is a set of four properties that the motif combination rules must satisfy in order to have certain desirable metrological properties.Motif methods may well provide useful techniques which complement rather than replace the traditional approach based on a mean line. It was found that many functional problems could be simulated very efficiently using motif methods. Examples of functional simulation via motif combination are illustrated in the paper.     

Stepwise-Graded Si3N4–SiC Ceramics with Improved Wear Properties

The processing of stepwise graded Si₃N₄/SiC ceramics by pressureless co-sintering is described. Here, SiC (high elastic modulus, high thermal expansion coefficient) forms the substrate and Si₃N₄ (low elastic modulus, low thermal expansion coefficient) forms the top contact surface, with a stepwise gradient in composition existing between the two over a depth of ∼1.7 mm. The resulting Si₃N₄ contact surface is fine-grained and dense, and it contains only 2 vol% yttrium aluminum garnet (YAG) additive. This graded ceramic shows resistance to cone-crack formation under Hertzian indentation, which is attributed to a combined effect of the elastic-modulus gradient and the compressive thermal-expansion-mismatch residual stress present at the contact surface. The presence of the residual stress is corroborated and quantified using Vickers indentation tests. The graded ceramic also possesses wear properties that are significantly improved compared with dense, monolithic Si₃N₄ containing 2 vol% YAG additive. The improved wear resistance is attributed solely to the large compressive stress present at the contact surface. A modification of the simple wear model by Lawn and co-workers is used to rationalize the wear results. Results from this work clearly show that the introduction of surface compressive residual stresses can significantly improve the wear resistance of polycrystalline ceramics, which may have important implications for the design of contact-damage-resistant ceramics.     

伍尔弗汉普敦市中心的公共空间概念设计，英国

2004年伍尔弗汉普敦(Wolverhampton)市政府授权伟信公司对该市中心公共空间进行全面改造概念设计和进一步的详细设计。市政府希望制定发展策略框架及实施步骤,以建造能够顺应大众和社团活动的核心主题公共空间。这些主题包括:安全城市、绿色城市、促进经济发展的城市等。现状是一些靠近大学区的地方出现的新的广场,如知识广场(LearningQuarter)、圣约翰城市村(StJohns’UrbanVillage),以改变城市中心看起来非常陈旧的状态。伟信公司接受了这项挑战,从深入城市的“表皮”入手,剖析城市的特征,以及所面临的问题,逐街分析。正如很多城市中心…