Emerging porous nanosheets: From fundamental synthesis to promising applications

Metal-organic framework(MOF)nanosheets and covalent organic framework(COF)nanosheets as emerging porous materials nanosheets have captured increasing attention owing to their attractive properties originating from the advantages of large lateral size,ultrathin thickness,tailorable physiochemical environment,flexibility and highly accessible active sites on surface,and the applications of them have been explored in a wide range of fields.Although MOF and COF nanosheets own many similar properties,their applications in various fields show significant differences,probably due to their different compositions and bonding modes.Hence,we summarize the recent progress of MOF and COF nanosheets by comparative analysis on their advantages and limitations in synthesis and applications,providing a more profound and full-scale perspective for researchers or beginners to understand this field.Herein,the categories of preparation methods of MOF and COF nanosheets are firstly discussed,including top-down and bottom-up methods.Secondly,the applications of MOF and COF nanosheets for separation,catalysis,sensing and energy storage are summarized.Finally,based on current achievements,we put forward our personal insights into the challenges and outlooks on the synthesis,characterizations,and promising applications for future research of MOF and COF nanosheets.     

Tumor-responsive copper-activated disulfiram for synergetic nanocatalytic tumor therapy

Exploring alternative biomedical use of traditional drugs in different disease models is highly important as it can reduce the cost of drug development and overcome several critical issues of traditional chemodrugs such as low chemotherapeutic efficiency,severe side effect,and drug resistance.Disulfiram(DSF),a clinically approved alcohol-aversion drug,was recently demonstrated tofeature tumor-growth suppression effect along with the co-administration of Cu²⁺species,but direct Cu²⁺administration mode might cause severe toxicity originating from low Cu²⁺accumulation into the tumor and nonspecific Cu²⁺distribution-induced cytotoxicity.Based on the intriguing drug-delivery performance of nanoscale metal-organic frameworks(MOFs),we herein construct HKUST nMOFs as the Cu²⁺self-supplying nanocarriers for efficient delivery of the D SF drug.The mildly acidic condition of tumor microenvironment initially triggered the release of Cu ions from HKUST nMOFs,which further reacted with the encapsulated DSF toform toxic Cu(DDTC)2(activation)for tumor chemotherapy.Especially,during the Cu(DDTC)2 complexation,Cu⁺species were formed concomitantly,triggering the intratumoral nanocatalytic therapy for the generation of reactive oxygen species to synergistically destroying the tumor cells/tissue.As a result,synergetic tumor-responsive chemotherapy and nanocatalytic therapy are enabled by DSF@HKU ST nanodrugs,as demonstrated by the dominant anticancer efficacy with satisfied biocompatibility both in vitro and in vivo.The present work offers a sophisticated strategy for tumor-responsive nontoxic-to-toxic therapeutic with high biocompatibility.     

网络安全技术及策略在校园网中的应用研究

计算机技术的快速发展,也导致网络安全形势日益严峻。网络安全技术对于人们日常生活、工作以及学习所产生的影响愈发深远。在校园网络系统中,部分非法入侵者会将目标设定到某一局域网当中,从而导致正常的教学秩序受到干扰,对此必须要采取一些行之有效的应对策略,来保障校园网的正常运行。     

非线性电阻电路图解法的数值计算

图解法是非线性电阻电路的基本解法之一。当非线性电阻的伏安特性由离散的数据点给出时,为了求出电路的数值解,提出了特性曲线重构和曲线求交算法。电路算例结果表明,本算法的计算精度高,速度较快,是一种实用的非线性电阻电路数值解法。     

10ns～500ns宽度连续可调的快速光脉冲发生器

脉宽可调的脉冲发生器常用于精密检测。本文阐述了一种运用叠加原理设计的脉冲宽度从10ns到500ns连续可调的快速光脉冲发生器。在驱动电路中应用了脉冲叠加原理。     

适用于高阶QAM解调的载波恢复算法及其实现验证

高阶正交幅度调制（QAM）系统中,随着QAM信号阶数的提高,频偏和相偏对系统解调性能的影响越敏感,其对同步性能的要求也越来越高。因此,必须在接收端对系统中的频偏和相偏进行更精确的补偿,使得接收端与发送端的载波信号达到同频同相,来提高解调系统的性能。本文首先简单介绍了两种常用两种面向判决的载波相位恢复算法,并利用MATLAB／Simulink为该算法搭建了系统仿真模型进行分析,然后给出了具体的实现方法并对其性能进行了分析。仿真结果表明,面向判决的载波恢复算法实现简单,稳态时抖动较小,非常适用于高阶QAM解调系统。     

镍钛形状记忆合金的开发应用

综述了镍钛形状记忆合金在国内外的开发应用情况。对今后的发展提出了建议。     

满足CE 要求和TUV 认证的励磁调节器设计及验证

为了使产品达到欧盟安全标准,进入欧盟的励磁系统设备必须通过CE认证。励磁调节器是励磁系统的控制核心。为了更进一步提高控制系统的要求,在满足CE的基础上,需要按照TUV认证的要求进行设计。通过分析励磁调节器的作用,在电器件选型、电磁兼容设计、结构件及柜体设计等方面与相关指令进行核对,完成了调节器装置的设计。该装置一次性通过TUV验证,证明装置设计的合理性,为电力系统其他装置进行CE及TUV认证提供参考。     

AP1000空气导流板垂直密封件制造质量控制研究

通过三门1#堆AP1000空气导流板垂直密封件制造的质量控制,总结了垂直密封件在制造过程中影响产品质量的两个技术难点,其一是折弯精度对产品质量的影响;其二是焊接变形对产品质量的影响。通过分析,确定了影响折弯精度和焊接变形的关键要素,提出了相应的控制方法。产品制造实践证明了这些变形控制方法的可行性和有效性,从而确保了产品的质量。本文总结的折弯精度控制和焊接变形控制方法对其他中厚型碳钢钢板在制造过程中的变形控制也有一定的借鉴意义。