Preparation and assessment of frozen-hydrated sections of mammalian tissue for electron microscopy and X-ray microprobe analysis

A system is described for preparing and examining frozen-hydrated sections of mammalian tissue, using commercially available equipment. An essential part of the system is a liquid nitrogen cooled vacuum transfer system. Minor modifications were required to interface the various manufacturers' equipment, and also to facilitate handling of specimens in the cryoultramicrotome. A variety of criteria indicates that our sections are truly frozen-hydrated, but negligible image contrast in the sections is a serious problem both for morphological work and X-ray microanalysis.     

The governance of psychological practice: Implications of American developments for Canadian psychology.

Describes 5 means of maintaining standards for psychological practice that are currently used in the US: (1) general and criminal law, (2) peer control, (3) federal regulations, (4) state boards of examiners in psychology, and (5) civil malpractice litigation. Their relevance to the Canadian context is discussed, especially with respect to the more restricted role of the Canadian federal government in professional affairs, the lower profile for civil rights, and the lower incidence of civil litigation in Canada. Recommendations made to ensure the exemplary practice of psychology include the increased use of peer control through peer review committees, increased organization of professional practice at the national level, and a closer liaison between professional associations and governing boards at the provincial level. (7 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Groundwork for creative research.

Examines the nature of and importance of creativity in scientists and relates these to the training functions in the university. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Gastric pacing improves emptying and symptoms in patients with gastroparesis

BACKGROUND & AIMS: No effective treatment is available for patients with gastroparesis refractory to standard medical therapy. The aim of this study was to investigate the effects of gastric pacing on gastric electrical activity, gastric emptying, and symptoms in patients with gastroparesis. METHODS: Nine patients with gastroparesis participated in this study. Four pairs of cardiac pacing wires were implanted on the serosa of the stomach. The protocol consisted of two portions: a temporary inpatient study period and an outpatient study for a period of 1 month or more. RESULTS: Gastric pacing entrained the gastric slow wave in all subjects and converted tachygastria in 2 patients into regular 3-cpm slow waves. Gastric emptying was significantly improved after the outpatient treatment with gastric pacing. The gastric retention at 2 hours was reduced from 77.0% +/- 3.3% to 56.6% +/- 8.6% (P < 0.05). Symptoms of gastroparesis were substantially reduced at the end of the outpatient treatment (1.51 +/- 0.46 vs. 2.84 +/- 0.61; P < 0.04). Eight of 9 patients no longer relied on jejunostomy tube feeding, and no adverse events were noted related to the pacing unit. CONCLUSIONS: Gastric pacing seems to be able to improve symptoms of gastroparesis and to accelerate gastric emptying in patients with gastroparesis. More controlled studies are necessary to further investigate the role of gastric pacing in clinical practice.     

In This Issue

Software Quality Journal -     

Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 9. Incorporation of planar waveguide technology

Incorporation of planar waveguide technology into a spectroelectrochemical sensor is described. In this sensor design, a potassium ion-exchanged BK7 glass waveguide was over-coated with a thin film of indium tin oxide (ITO) that served as an optically transparent electrode. A chemically selective film was spin-coated on top of the ITO film. The sensor supported five optical modes at 442 nm and three at 633 nm. Investigations on the impact of the ITO film on the optical properties of the waveguide and on the spectroelectrochemical performance of the sensor are reported. Sensing was based on the change in attenuation of light propagated through the waveguide resulting from an optically absorbing analyte. By applying either a triangular or square wave excitation potential waveform, electromodulation of the optical signal has been demonstrated with Fe(CN)6(3-/4-) as a model electroactive couple that partitions into a PDMDAAC-SiO2 film [where PDMDAAC = poly(dimethyldiallylammonium chloride)] and absorbs at 442 nm.     

Direct vapor phase growth process and robust photoluminescence properties of large area MoS2 layers

There has been growing research interest in the use of molybdenum disulfide in the fields of optoelectronics and energy harvesting devices, by virtue of its indirect-to-direct band gap tunability. However, obtaining large area thin films of MoS2 for future device applications still remains a challenge. In the present study, the amounts of the precursors （S and MOO3） were varied systematically in order to optimize the growth of highly crystalline and large area MoS2 layers by the chemical vapor deposition method. Careful control of the amounts of precursors was found to the key factor in the synthesis of large area highly crystalline flakes. The thickness of the layers was confirmed by Raman spectroscopy and atomic force microscopy. The optical properties and chemical composition were studied by photoluminescence （PL） and X-ray photoelectron spectroscopy. The emergence of strong direct excitonic emissions at 1.82 eV （A-exciton, with a normalized PL intensity of -55 × 10^3） and 1.98 eV （B-exciton, with a normalized PL intensity of -5 × 10^3） of the sample at room temperature clearly indicates the high luminescence quantum efficiency. The mobility of the films was found to be 0.09 cm^2/（V.s） at room temperature. This study provides a method for the controlled synthesis of high-quality two-dimensional （2D） transition metal dichalcogenide materials, useful for applications in nanodevices, optoelectronics and solar energv conversion.     

A uniplanar printed antenna with an inverted L‐shaped coupling feed for LTE/GSM/DCS/PCS/UMTS operations

A novel uniplanar printed antenna with a total size of 115 × 40 mm² is proposed for mobile device application. By using an inverted L‐shaped feeding mechanism and a meandered shorting strip, a dual‐band operation with wideband characteristic can be achieved. Here, the lower operating band is able to cover the LTE 700 and GSM 850/900 operations, while the higher operating band allows DCS 1800, PCS 1900, UMTS, and LTE 2300 operations. Furthermore, in order to increase the bandwidth of the higher operating band so that LTE 2500 operation can also be covered, an additional parasitic stub is attached to the feed line to excite a resonant frequency at around 2.72 GHz. Parametric studies via simulation are carried out, and prototype of the proposed antenna is also experimentally investigated to validate the simulated results. © 2012 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2012.