Acquisition and reversal of taste/tactile discrimination after forebrain noradrenaline depletion.

Assessed the role of noradrenaline (NA) on the acquisition of an aversively motivated discrimination task and its reversal. A conditioned taste aversion procedure was used. NA depletions were achieved through 2 pharmacological means: systemic N-2 chloroethyl-N-ethyl-2-bromo-benzylamine (DSP4) and destruction of the dorsal noradrenergic bundle (DNAB) with 6-hydroxydopamine (6-OHDA). Both procedures caused marked reductions of NA in the frontal cortex and hippocampus. In neither of the studies (Exp 1, DSP4 and Exp 2, DNAB) were there any significant changes between controls and NA-depleted rats in either the rate of acquisition of the original discrimination (Phase 1) or the subsequent reversal (Phase 2). This occurred irrespective of which of the 2 stimuli (a taste cue or a tongue-tactile cue) initially was used as the conditioned stimulus/stimuli (CS) (the stimulus first followed by contingent administration of lithium chloride and later, by saline injections). Thus NA does not appear to be critically involved in the acquisition and reversal of a taste/tactile discrimination task. The significance of forebrain NA for other discrimination tasks is discussed. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

应用酶放大电极的免疫测定

该文评述了应用酶放大电极的免疫测定法的进展,从原理和应用两方面进行了探讨.着重介绍了作者所在实验室在90年代以来的相关工作.     

Study of lanthanum-deficient compositions in the systems La-Cu-O and La-Sr-Cu-O

The effect of varying lanthanum composition upon the formation of the nonsuperconducting La_1.67Sr_0.33Cu₂O_5– and the stoichiometry variation tolerance of the ternary system La_2–xSr_xCuO₄ (with x=0 and 0.15) were investigated using a variety of techniques. Results indicate that total conversion to La₂CuO₄ from freeze-dried precursors with an LaCu = 2.001 ratio is achieved after sintering (1253 K, 12 h) and annealing in oxygen (773 K, 6 h). Small variations in the stoichiometry of solids La_2–xSr_xCuO₄ with x=0 and 0.15 were detected. Lanthanum-deficient composition in the ternary system induces the formation of the non-superconducting phase whose stoichiometry is better represented by La_1.60Sr_0.40Cu₂O_5–. The temperature-programmed reduction profiles of the cuprates can be associated with the formation of more or less stable intermediates.     

The nature of active sites for the oxidation of methane on La-based perovskites

Highly crystalline, monophasic LaFeO₃ and LaCoO₃ perovskites, prepared by the explosion method, are shown to be heterogeneous at surface level. The outmost atomic layers of these perovskites contain high concentrations of carbonate-type species. Their specific activities for methane combustion are in fact identical to La₂O₂CO₃ and air-exposed La₂O₃. These results compared with pertinent data from the literature hint that surface heterogeneity may be often present in mixed oxides catalysts.     

Compatibilization of Poly(propylene)/Polyamide 6 Blends with Functionalized Poly(propylene)s Prepared with Metallocene Catalyst

Summary: Propylene was copolymerized with 10‐undecen‐1‐ol using dimethylsilanylbis(2‐methyl‐4‐phenyl‐1‐indenyl)zirconium dichloride as catalyst and MAO and TIBA as cocatalysts. Comonomer incorporations from 0.1 to 0.9 mol‐% (0.5 to 3.6 wt.‐%) were obtained. These hydroxyl functionalized copolymers were applied as compatibilizers to PP/PA6 blend with a composition of 70/30. For comparison, hydroxyl functionalized polyethylene prepared with metallocene catalyst and commercial MAH grafted ethylene butyl acrylate (E/BA/MAH) and poly(propylene) (PP‐g‐MAH) were also used as compatibilizers. Effects of the compatibilizers on morphology and mechanical and thermal properties of the blends were studied. Enhanced adhesion between the blend components was observed in morphology and dynamic mechanical studies. Although improvement in toughness was not as pronounced as expected, there were indications that the hydroxyl functionalized propylene copolymers prepared with metallocene catalysts could serve as a new type of compatibilizer in polymer blends.

SEM micrograph (5 000×) of an PP/PA6/PP‐co‐OH4 blend.     

Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor

Background  

Particulate air pollution has been associated with lung and cardiovascular disease, for which lung inflammation may be a driving mechanism. The pro-inflammatory cytokine, tumor necrosis factor (TNF) has been suggested to have a key-role in particle-induced inflammation.     

Phosphorus poisoning of ZSM-5 and Pt/ZSM-5 zeolite catalysts in diesel exhaust gas conditions

Powdered ZSM-5 and Pt/ZSM-5 catalysts were studied as fresh and after two treatments: hydrothermal ageing and phosphorus poisoning in hydrothermal conditions. The results showed that the deactivating effect of phosphorus was stronger than the effect of the hydrothermal treatment alone. Phosphorus had accumulated in the samples during the ageing. The decrease in specific surface area and increase in Pt particle size indicated the possible reasons for deactivation.     

Robust output regulation and the preservation of polynomial closed‐loop stability

In this paper, we study the robust output regulation problem for distributed parameter systems with infinite‐dimensional exosystems. The main purpose of this paper is to demonstrate the several advantages of using a controller that achieves polynomial closed‐loop stability, instead of a one stabilizing the closed‐loop system strongly. In particular, the most serious unresolved issue related to strongly stabilizing controllers is that they do not possess any known robustness properties. In this paper, we apply recent results on the robustness of polynomial stability of semigroups to show that, on the other hand, many controllers achieving polynomial closed‐loop stability are robust with respect to large and easily identifiable classes of perturbations to the parameters of the plant. We construct an observer based feedback controller that stabilizes the closed‐loop system polynomially and solves the robust output regulation problem. Subsequently, we derive concrete conditions for finite rank perturbations of the plant's parameters to preserve the closed‐loop stability and the output regulation property. The theoretical results are illustrated with an example where we consider the problem of robust output tracking for a one‐dimensional heat equation.Copyright © 2013 John Wiley & Sons, Ltd.     

Smouldering Combustion in Loose-Fill Wood Fibre Thermal Insulation: An Experimental Study

A bench-scale experimental setup has been used to study the conditions necessary for smouldering ignition in four types of loose-fill wood fibre thermal insulation, and to study the development of the smouldering process. The products varied with regard to wood species, grain size and fire retardant chemical additives. The test material was placed in an insulated open top container and heated from below. Temperatures within the sample and mass loss were measured during the tests. Both the fibre size and the level of added fire retardant seem to influence the smouldering ignition. Two different types of smouldering were identified in this study. Materials undergoing smouldering Type 1 obtained maximum temperatures in the range 380°C to 440°C and a total mass loss of 40 wt% to 50 wt%. Materials undergoing smouldering Type 2 obtained maximum temperatures in the range 660°C to 700°C and a total mass loss of 80 wt% to 90 wt%. This implies that Type 2 smouldering involves secondary char oxidation, which represents a risk for transition to flaming combustion and thereby a considerable fire hazard. This has been an exploratory project and the results must therefore be considered as indicative. The findings may, however, have implications for fire safety in the practical use of loose-fill wood fibre insulation in buildings, and further experimental studies should be performed with this in mind to obtain more knowledge about the topic.