Viscoplastic-dynamic crack propagation: Experimental and analysis research for crack arrest applications in engineering structures

The many practical situations in which the initiation of rapid crack propagation cannot be absolutely precluded and where the consequences of a large scale fracture would be catastrophic mandate the development and use of crack arrest fracture mechanics technology. Most currently applied procedures utilize linear elastic analyses and corresponding material fracture property characterizations. Even though the theoretical basis for the use of this level of approach is incomplete, selected practical applications are described in this paper that show that these can still be effectively made. In addition, to address the current deficiencies and to treat those conditions where small-scale yielding conditions are clearly not satisfied, more advanced viscoplastic-dynamic analyses are also being developed. An approach is described in this paper that performs well-instrumented fracture propagation experiments in concert with viscoplastic dynamic finite-element simulations. This approach, currently used to quantify critical values of the T ^* crack tip characterizing parameter developed by Atluri, is being pursued in order to provide transferable material crack arrest toughness values in the regime where viscoplastic-dynamic conditions dominate.

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Résumé Les nombreuses situations pratiques où l'amorçage d'une croissance rapide d'une fissure ne peut être formellement prévue, et où les conséquences d'une rupture à grande échelle seraient catastrophiques, requièrent le développement et l'usage de la technique de mécanique de la rupture du point de vue de l'arrêt de fissuration.La plupart des procédures actuelles recourent à des analyses linéaires et élastique et aux caractérisations correspondantes des propriétés de résistance à la rupture des matériaux. Même si la base théorique pour une approche de ce niveau est encore incomplète, des applications pratiques spécifiques peuvent en être faites, ainsi qu'on le décrit dans l'étude. En outre, pour répondre aux déficiences actuelles, et pour traiter les conditions qui ne peuvent s'accomoder des conditions de plastification à petite échelle, on développe une analyse dynamique viscoplastique plus évoluée. Dans l'étude, on décrit une approche qui associe des essais de propagation de fissure dûment instrumentés et des simulations dynamiques viscoplastiques par éléments finis. Cette approche, qui est déjà utilisée pour établir les valeurs critiques du paramètres T ^* développé par Atluri pour caractériser l'extrémité de la fissure, est approfondie en vue de fournir des valeurs transférables de la ténacité du matériau vis-à-vis de l'arrêt de propagation d'une fissure, là où prédominent des conditions de viscoplasticité dynamique.

     

Modeling stump biomass of stands using harvester measurements for adaptive energy wood procurement systems

The value and volumes of industrial stump fuel supply are increasing for energy production. Accurate estimates of aboveground and belowground biomass of trees are important when estimating the potential of stumps as a bioenergy source. In this study two stump biomass equations were adapted and tested using them as calibrated stump biomass models computed as the cumulative sum by a local stand. In addition, variables derived from stem measurements of the forest harvester data were examined to predict stump biomass of a stand by applying regression analysis. The true stump yield (dry weight) was used as the reference data in the study. Both biomass models performed well (adjusted R² ˜ 0.84) and no advance was found in using other stem dimensions as independent variables in the model. The stand-level model can be used in innovative stump biomass prediction tools for increasing efficiency of energy wood procurement planning to stands within a certain area. In practice, wood procurement managers would need to adapt developed system and decide whether the degree of accuracy/precision provided by the models is acceptable in their local stand harvesting conditions.     

Adrenal hemangioma: review of the literature

Initially thought to act as tissue replacement, cultured epithelial allografts are now known to work by providing a potent stimulus for healing. In a similar fashion, we believe that traditional autografts may also provide a stimulus to help heal chronic wounds, thus acting as pharmacological agents for healing. We attempted to assess the possibility of augmenting the stimulatory properties of donor skin by initiating the healing process in the donor region prior to grafting. This was accomplished by pre-wounding the donor area 3 days prior to harvesting the donor skin. We compared these 'pre-wounded' grafts to those harvested immediately. Two patients underwent punch grafting for chronic leg ulceration. Half of the ulcer was grafted with donor skin harvested from an area that was pre-wounded and the other half from freshly harvested skin. We evaluated each for improvement of granulation tissue and degree of edge effect (migration of the previously dormant wound edges). All the grafts did well. There was marked improvement in granulation tissue in the ulcer bed after grafting, and the obvious presence of an edge effect. The edge effect was increased on the site where the pre-wounded grafts were placed. It may be possible to augment the growth stimulatory properties of donor skin. This may offer therapeutic options in patients with chronic wounds.     

Equality sets of prefix morphisms and regular star languages

We consider equality sets of prefix morphisms, that is, sets E(g₁,g₂)={w|g₁(w)=g₂(w)}, where g₁ and g₂ are prefix morphisms. Recall that a morphism g is prefix if, for all different letters a and b, g(a) is not a prefix of g(b). We prove a rather surprising equality on families of languages, namely, that the family of regular star languages coincides with the family of languages of form πA(E(g₁,g₂)) for some prefix morphisms g₁ and g₂, and a projection πA which deletes the letters not in A.     

Microfluidics-Based Force Spectroscopy Enables High-Throughput Force Experiments with Sub-Nanometer Resolution and Sub-Piconewton Sensitivity

Several techniques have been established to quantify the mechanicals of single molecules. However, most of them show only limited capabilities of parallelizing the measurement by performing many individual measurements simultaneously. Herein, a microfluidics-based single-molecule force spectroscopy method, which achieves sub-nanometer spatial resolution and sub-piconewton sensitivity and is capable of simultaneously quantifying hundreds of single-molecule targets in parallel, is presented. It relies on a combination of total internal reflection microscopy and microfluidics, in which monodisperse fluorescent beads are immobilized on the bottom of a microfluidic channel by macromolecular linkers. Application of a flow generates a well-defined shear force acting on the beads, whereas the nanomechanical linker response is quantified based on the force-induced displacement of individual beads. To handle the high amount of data generated, a cluster analysis which is capable of a semi-automatic identification of measurement artifacts and molecular populations is implemented. The method is validated by probing the mechanical response polyethylene glycol linkers and binding strength of biotin–NeutrAvidin complexes. Two energy barriers (at 3 and 5.7 Å, respectively) in the biotin–NeutrAvidin interaction are resolved and the unfolding behavior of talin's rod domain R3 in the force range between 1 to ≈10 pN is probed.     

建筑和教育

建筑是条路径，是个无止境的过程，不能止于一点或一种风格。教育可以打开眼界、开阔思想，好的建筑教育不会给出即成固定的模式或样板，而只会激发起欲望、勇气和智慧。     

Effects of Silage Fermentation and Post-ruminal Casein Supplementation in Lactating Dairy Cows: 1—Diet Digestion and Milk Production

Two silages were prepared from the first-cut sward of timothy-meadow fescue and wilted to a dry matter (DM) content of 300 g kg^-1. One was ensiled with the addition of a formic-acid-based additive (4 litres formic acid (FA) per tonne) and the other with the addition of a bacterial inoculant (LAB) at a rate of 5×10⁶ colony forming units g^-1. Both silages were well preserved, but the extent of fermentation was greater in LAB-silage than in FA-silage as indicated by a lower concentration of water soluble carbohydrates (68 vs 177 g kg^-1 DM) and a higher concentration of lactic acid (147 vs 32 g kg^-1 DM). Four Ayrshire cows were used in a 4×4 Latin square experiment with 21-day periods to study the effects of silage fermentation and postruminal casein supplementation on silage intake, nutrient supply and milk production. The four treatments were FA-silage without casein (FA-0), LAB-silage without casein (LAB-0), FA-silage with casein (FA-C) and LAB-silage with casein (LAB-C). Both silages were given ad libitum with 8 kg day^-1 of barley without or with 400 g day^-1 of casein infused into the duodenum. Organic matter digestibility was lower (0·723 vs 0·753; P<0·01) for FA-silage than for LAB-silage. Cows offered FA-silage had a higher molar proportion of acetate and a lower proportion of propionate in ruminal fluid than cows offered LAB-silage. Microbial protein synthesis estimated from the output of purine derivatives in urine was greater (288 vs 260 g N day^-1; P<0·05) for cows given FA-silage compared with LAB-silage. Feeding LAB-treated silage tended (P<0·10) to decrease silage DM intake compared with FA-treated silage (10·61 vs 11·77 kg DM day^-1). Silage composition did not affect significantly milk yield or milk composition. Casein infusion increased milk yield (25·1 vs 27·1 kg day^-1; P<0·05), milk protein content (32·4 vs 33·8 g kg^-1; P<0·05) and protein yield (808 vs 905 g day^-1; P<0·01). The responses were similar for both silages. © 1997 SCI.     

Identification and Ruminal Outflow of Long-Chain Fatty Acid Biohydrogenation Intermediates in Cows Fed Diets Containing Fish Oil

The abundance of 20- to 24-carbon fatty acids in omasal digesta of cows fed grass silage-based diets supplemented with 0 (Control) and 250 g/day of fish oil (FO) was examined to investigate the fate of long-chain unsaturated fatty acids in the rumen. Complimentary argentation thin-layer chromatography and gas-chromatography mass-spectrometry analysis of fatty acid methyl esters and corresponding 4,4-dimethyloxazoline derivatives prepared from fish oil and omasal digesta enabled the structure of novel 20- to 22-carbon fatty acids to be elucidated. Compared with the Control, the FO treatment resulted in the formation and accumulation of 27 novel 20- and 22-carbon biohydrogenation intermediates containing at least one trans double bond and the appearance of cis-14 20:1, 20:2n-3, 21:4n-3 and 22:3n-6 not contained in fish oil. No conjugated ≥20-carbon fatty acids were detected in Control or FO digesta. In conclusion, fish oil in the diet results in the formation of numerous long-chain biohydrogenation intermediates in the rumen of lactating cows. Comparison of the intake and flow of 20-, 21- and 22-carbon fatty acids at the omasum in cows fed the Control and FO treatments suggests that the first committed steps of 20:5n-3, 21:5n-3 and 22:6n-3 hydrogenation in the rumen involve the reduction and/or isomerisation of double bonds closest to the carboxyl group.     

Raising milk energy content retards gastric emptying of lactose in lactose-intolerant humans with little effect on lactose digestion

Lactose digestion improves when the energy content of a meal is raised, perhaps due to delayed gastric emptying; however, this has not been demonstrated directly. It is not known whether lactose-intolerant subjects should consume full-fat or high energy milk instead of half-skimmed milk. In this study, breath 13CO2 and hydrogen (H2) measurements were combined to assess simultaneously the effect of increasing milk energy content on gastric emptying, digestion, and tolerance of lactose. On two separate days, 11 adult lactose maldigesters ingested, in the fasting state, a single dose of 710 kJ half-skimmed milk or 1970 kJ high energy milk. Both contained 18 g lactose and were supplemented with 100 mg 13C-glycine for breath 13CO2 measurement. For 6 h after milk ingestion, samples of expired breath were collected, and subjects scored their symptoms on a four-grade questionnaire. Gastric emptying was measured from excretion of breath 13CO2. The mean gastric emptying half-time was significantly longer after ingestion of high energy milk than after half-skimmed milk (84 +/- 4 vs. 64 +/- 4 min, P = 0.004). The mean area under the breath H2 excretion curve measured for 6 h was 330 +/- 61 microL/L after subjects consumed high energy milk vs. 470 +/- 82 microL/L after they consumed half-skimmed milk (P = 0.07). Mean symptom scores did not differ after ingestion of the two milks, but only two subjects experienced disturbing symptoms after high energy milk ingestion compared with five subjects after ingestion of half-skimmed milk (P = 0.56). Although ingestion of high energy milk delayed the gastric emptying of lactose for significantly longer than the ingestion of half-skimmed milk (P < 0.01), it did not lead to significant improvement in symptoms and reflected only a trend toward improved lactose digestion (P = 0.07), as measured by the area under the breath H2 excretion curve. These results indicate that it is not beneficial for most lactose-intolerant subjects to replace consumption of half-skimmed milk by milk with a higher energy content.     

Flexible Manufacturing Systems' compliance to the safety standards

Safety improvements of Flexible Manufacturing Systems (FMSs) are improving usability of the system usability and also the competitiveness of the manufacturing. The aims of this study were 1) to analyze the deficiencies in and the risks of flexible manufacturing system (FMS) implementations 2) to clarify whether the systems meet the demands of safety standards and 3) to suggest safety system improvements. The study was made by using the Safety Analysis for Production Automation and the Safety Checklist for FMSs. The data were gathered by interviewing key managers and workers employed by 22 Finnish companies with FMS implementations. The study showed that although the companies considered the FM systems as one of their safest functions in the workshops, many of the systems do not fulfill the most common requirements of the safety standards. The requirements were met by 70% of the targets studied. Installation and maintenance functions best meet these requirements, whereas the layout of the systems and their mechanical structure were the most poorly designed areas. Especially poor were the safety and ergonomics of the loading/unloading stations. This paper presents additional information about the deficiencies found in the FM-systems and companies' involvement in them. The results shed new light on safety and ergonomic aspects to be considered in designing and using FM-systems. The data can be used to help industry meet safety demands and to improve the efficiency of new FMS implementations.