Attenuation compensation for cardiac single-photon emission computed tomographic imaging: Part 1. Impact of attenuation and methods of estimating attenuation maps

Attenuation is believed to be one of the major causes of false-positive cardiac single-photon emission computed tomographic (SPECT) perfusion images. This article reviews the physics of attenuation, the artifacts produced by attenuation, and the need for scatter correction in combination with attenuation correction. The review continues with a comparison of the various configurations for transmission imaging that could be used to estimate patient specific attenuation maps, and an overview of how these are being developed for use on multiheaded SPECT systems, including discussions of truncation, noise, and spatial resolution of the estimated attenuation maps. Ways of estimating patient specific attenuation maps besides transmission imaging are also discussed.     

A distribution-free tabular CUSUM chart for autocorrelated data

A distribution-free tabular CUSUM chart called DFTC is designed to detect shifts in the mean of an autocorrelated process. The chart's Average Run Length (ARL) is approximated by generalizing Siegmund's ARL approximation for the conventional tabular CUSUM chart based on independent and identically distributed normal observations. Control limits for DFTC are computed from the generalized ARL approximation. Also discussed are the choice of reference value and the use of batch means to handle highly correlated processes. The performance of DFTC compared favorably with that of other distribution-free procedures in stationary test processes having various types of autocorrelation functions as well as normal or nonnormal marginals.     

Transient Charging and Discharging Behaviors of Border Traps in the Dual-Layer HfO2/SiO2 High- κ Gate Stack Observed by Using Low-Frequency Charge Pumping Method

Transient charging and discharging of border traps in the dual-layer HfO₂/SiO₂ high-kappa gate stack have been extensively studied by the low-frequency charge pumping method with various input pulse waveforms. It has been demonstrated that the exchange of charge carriers mainly occurs through the direct tunneling between the Si conduction band states and border traps in the HfO₂ high-kappa dielectric within the transient charging and discharging stages in one pulse cycle. Moreover, the transient charging and discharging behaviors could be observed in the time scale of 10^-8- 10^-4 s and well described by the charge trapping/detrapping model with dispersive capture/emission time constants used in static positive bias stress. Finally, the frequency and voltage dependencies of the border trap area density could also be transformed into the spatial and energetic distribution of border traps as a smoothed 3-D mesh profiling     

Influence of microstructure and phase composition on the nanoindentation characterization of bioceramic materials based on hydroxyapatite

The aim of the study was to investigate the influence of microstructure and phase composition on the mechanical behaviour of hydroxyapatite (HAp) and biphasic HAp/β-tricalcium phosphate (β-TCP) bioceramic materials using nanoindentation. The formation of β-TCP phase in the HAp ceramic had the predominant influence on the nanomechanical properties of compact ceramics. For investigated microstructures there appear to be a slight decrease in the elastic modulus with increasing load and a higher decrease in hardness, which are in agreement with upper bounds of the results reported in literature. Maximal value of reduced modulus and hardness is yielded with pure HAp, and is measured to be 133.76 GPa for average grain size of 3 μm and 12.18 GPa for average grain size of 140 nm, respectively. The average modulus and hardness results for HAp/β-TCP ceramics with higher (101.61 GPa, 6.76 GPa) and lower grain size (115.72 GPa, 8.76 GPa) show sufficient mechanical properties in order to serve as hard tissue replacement material.     

IMPACT MODELS FOR SITING UNDESIRABLE FACILITIES

ABSTRACT Location models continue to be recognized as valuable tools for providing insights to decision makers regarding the impacts and relative attributes of potential planning alternatives. An important area of current location modeling research has been devoted to issues associated with siting undesirable facilities. A number of approaches for addressing equity and community impact in locating these facilities are reviewed and developed in this article. Application results for the planning models presented in this article demonstrate their relative benefits and solution characteristics.     

Multivariate control charts based on loss functions

A new method is given for designing multivariate control charts based on loss functions. The average run length contours of the proposed procedure correspond closely to the contours of the expected loss. The approach is much more efficient in terms of resulting statistical properties than the method of Mohebbi and Hayre (1989). Several bivariate examples are considered.     

A programmable integrated digital controller for switching converters with dual-band switching and complex pole-zero compensation

The design of a 0.6-/spl mu/m CMOS programmable integrated digital PID controller for a buck converter is presented. Several novel features are implemented. These include: 1) a dual-band switching scheme for sampling the output voltage for better output resolution; 2) a dual-band switching PWM generator with a modified tapped delay line for area efficiency; 3) a VCO driving a counter to serve as an ADC; 4) a programmable PID compensator employing variable integration times for enhancing accuracy and stability; and 5) complex pole-zero cancellation in extending the bandwidth of the control loop. The converter is designed for variable output applications, and the fast digital loop achieves a tracking time of 50 /spl mu/s for a 1-V step change of the reference voltage. The converter switches at 1 MHz and attains a maximum efficiency of 90% when delivering a load of 125 mW.     

A Breath Ammonia Sensor Based on Conducting Polymer Nanojunctions

We present an ammonia sensor for human breath analysis based on electrically conducting polymer nanojunctions. Each nanojunction is formed by bridging a pair of gold nanoelectrodes on a silicon chip separated by a small gap (<60 nm) with electrodeposited polyaniline. The signal transduction mechanism of the sensor is the change in the nanojunction conductance as a result of polymer dedoping by ammonia. The sensor response to human breath is validated by comparison with a reference method for detection of ammonium ion combined with an optimized breath ammonia trapping system. The nanojunction sensor is capable of in situ detection of parts per billion (ppb) levels of ammonia in human breath.