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51.
Gleevec是抑制致癌的融合蛋白BCR-ABL的一种分子靶向治疗药物,BCR-ABL是一种与慢性髓细胞性白血病(CML)有关的酪氨酸激酶抑制剂。用Gleevec选择性地抑制BCR-ABL活性在治疗CML中显示出很好的效果,特别是在CML慢性期,因此,监测疗效非常重要。现就Gleevec的研究进展及如何监测其在CML中的疗效作一简单综述。 相似文献
52.
采用正交试验对汽轮机叶片用X20Cr13钢进行了热处理工艺研究,以获得该钢的最佳热处理工艺,并在回火后以不同的速度冷却,以揭示冷却速度对钢的回火脆性的影响。结果,X20Cr13钢的最佳热处理工艺为900℃油淬或风冷,670℃回火,风冷。 相似文献
53.
XIAKe-yu YURong-jin MENGHua-mao 《半导体光子学与技术》2004,10(2):82-85
By stretching the rod waveguide with different velocities in opposite directions, the tapered waveguide can be fabricated. In condition of taking no account of volume expansion caused by heating and under the assumptions of volume conservation,the rod waveguide can be stretched freely in the heated region without being stretched outside of the heated region. A model,which shows the relation of the transition shape and the two factors, that is the ratio of two velocity and the heated region length, is presented for the shape of the taper transition through mathematic deduction. Based on this model, a desired tapered waveguide can be fabricated. The tapered waveguide are widely used for fabricating tapered fiber couplers and sensors. In addition, the conclusion can be used for fabricating fused fiber coupler. 相似文献
54.
55.
The simulation and analysis of S-shaped waveguide bend are presented.Bend radius larger than 30 mm assures less than 0.5 dB radiation loss for a 4-μm-wide silicon-on-insulator waveguide bend with 2-μm etch depth.Intersection angle greater than 20° provides negligible crosstalk (<-30 dB) and very low insertion loss.Any reduction in bend radius and intersection angle is at the cost of the degradation of characteristics of bent waveguide and intersecting waveguide, respectively. 相似文献
56.
Similarity retrieval of iconic image database 总被引:3,自引:0,他引:3
The perception of spatial relationships among objects in a picture is one of the important selection criteria to discriminate and retrieve the images in an iconic image database system. The data structure called 2D string, proposed by Chang et al., is adopted to represent symbolic pictures. The 2D string preserves the objects' spatial knowledge embedded in images. Since spatial relationship is a fuzzy concept, the capability of similarity retrieval for the retrieval by subpicture is essential. In this paper, similarity measure based on 2D string longest common subsequence is defined. The algorithm for similarity retrieval is also proposed. Similarity retrieval provides the iconic image database with the distinguishing function different from a conventional database. 相似文献
57.
MRI fuzzy segmentation of brain tissue using neighborhood attraction with neural-network optimization. 总被引:11,自引:0,他引:11
Shan Shen William Sandham Malcolm Granat Annette Sterr 《IEEE transactions on information technology in biomedicine》2005,9(3):459-467
Image segmentation is an indispensable process in the visualization of human tissues, particularly during clinical analysis of magnetic resonance (MR) images. Unfortunately, MR images always contain a significant amount of noise caused by operator performance, equipment, and the environment, which can lead to serious inaccuracies with segmentation. A robust segmentation technique based on an extension to the traditional fuzzy c-means (FCM) clustering algorithm is proposed in this paper. A neighborhood attraction, which is dependent on the relative location and features of neighboring pixels, is shown to improve the segmentation performance dramatically. The degree of attraction is optimized by a neural-network model. Simulated and real brain MR images with different noise levels are segmented to demonstrate the superiority of the proposed technique compared to other FCM-based methods. This segmentation method is a key component of an MR image-based classification system for brain tumors, currently being developed. Index Terms-Improved fuzzy c-means clustering (IFCM), magnetic resonance imaging (MRI), neighborhood attraction, segmentation. 相似文献
58.
化学还原法制备纳米铜粉的研究 总被引:18,自引:1,他引:17
本文采用KBH4在液相中化学还原CuSO4,并加入KOH和络合剂EDTA ,制得了纳米级的纯净的铜粉 ,通过调整反应物的浓度 ,可以消除Cu2 O等杂质。制备的纳米铜粉还存在一定程度的团聚 ,需试验加入分散剂来改善。 相似文献
59.
J Shan 《Canadian Metallurgical Quarterly》1997,32(6):323-325
Between 1990 and 1992, external sphincter repair was performed in 20 patients rendered faecally incontinent after earlier fistula surgery. All were improved, 13 (65%) achieving Grade 1 or 2 continence. Postoperative ultrasound was useful in explaining the sub-optimal outcome of 3 patients who still had defects. Clinical outcome in female patients was better than in male patients. Clinical outcome was not related to the results of preoperative manometry, the site of external sphincter damage, the use of a stoma, or the occurrence of wound complications. External sphincter repair for faecal incontinence after fistula surgery achieves good results in the majority of patients. 相似文献
60.
StudyonHotDeformationCracksofSteelD2UsingProcesingMapGaoShan,LiuXianghua,WangGuodongABSTRACTThehotdeformationbehaviorsofsteel... 相似文献